Related papers: Normative Cerebral Perfusion Across the Lifespan
Motivation: Characterising the changes in cortical morphology across the lifespan is fundamental for a range of research and clinical applications. Most studies to date have found a monotonic decrease in commonly used morphometrics, such as…
Timely, accurate and reliable assessment of fetal brain development is essential to reduce short and long-term risks to fetus and mother. Fetal MRI is increasingly used for fetal brain assessment. Three key biometric linear measurements…
More than 13 million people suffer from ischemic cerebral stroke worldwide each year. Thrombolytic treatment can reduce brain damage but has a narrow treatment window. Computed Tomography Perfusion imaging is a commonly used primary…
Brain charts have emerged as a highly useful approach for understanding brain development and aging on the basis of brain imaging and have shown substantial utility in describing typical and atypical brain development with respect to a…
A network-based approach is presented to investigate the cerebrovascular flow patterns during atrial fibrillation (AF) with respect to normal sinus rhythm (NSR). AF, the most common cardiac arrhythmia with faster and irregular beating, has…
Diffuse correlation spectroscopy (DCS) analyzes the autocorrelation function of photons scattered by red blood cells, enabling non-invasive, continuous measurement of deep tissue blood flow at the bedside. Multi-layer DCS models (two- and…
Cerebral blood flow is a critical metric for cerebrovascular monitoring, with applications in stroke detection, brain injury evaluation, aging, and neurological disorders. Non-invasively measuring cerebral blood dynamics is challenging due…
Brain age prediction based on neuroimaging data could help characterize both the typical brain development and neuropsychiatric disorders. Pattern recognition models built upon functional connectivity (FC) measures derived from resting…
The purpose of this study is to present and compare three denoising diffusion probabilistic models (DDPMs) that generate 3D $T_1$-weighted MRI human brain images. Three DDPMs were trained using 80,675 image volumes from 42,406 subjects…
Background: Understanding healthy human brain function is crucial to identify and map pathological tissue within it. Whilst previous studies have mapped intracranial EEG (icEEG) from non-epileptogenic brain regions, these maps do not…
Directional fluid flow in perivascular spaces surrounding cerebral arteries is hypothesized to play a key role in brain solute transport and clearance. While various drivers for pulsatile flow, such as cardiac or respiratory pulsations, are…
Accurate identification of brain function is necessary to understand the neurobiology of cognitive ageing, and thereby promote well-being across the lifespan. A common tool used to investigate neurocognitive ageing is functional magnetic…
Applying machine learning to real-world medical data, e.g. from hospital archives, has the potential to revolutionize disease detection in brain images. However, detecting pathology in such heterogeneous cohorts is a difficult challenge.…
Blood-based biomarkers underpin clinical diagnosis and management, yet their interpretation relies largely on fixed population reference intervals that ignore stable, intra-patient variability. As such, population-based interpretation can…
Cortical surface analysis has gained increased prominence, given its potential implications for neurological and developmental disorders. Traditional vision diffusion models, while effective in generating natural images, present limitations…
The CT perfusion (CTP) is a medical exam for measuring the passage of a bolus of contrast solution through the brain on a pixel-by-pixel basis. The objective is to draw "perfusion maps" (namely cerebral blood volume, cerebral blood flow and…
Identifying unusual brain activity is a crucial task in neuroscience research, as it aids in the early detection of brain disorders. It is common to represent brain networks as graphs, and researchers have developed various graph-based…
Adolescence is marked by rapid development of executive function. Mounting evidence suggests that executive function in adults may be driven by dynamic control of neurophysiological processes. Yet, how these dynamics evolve over adolescence…
In ischemic stroke, leptomeningeal collaterals can provide compensatory blood flow to tissue at risk despite an occlusion, and impact treatment response and infarct growth. The purpose of this work is to test the hypothesis that local…
Dementia disorders are increasingly becoming sources of a broad range of problems, strongly interfering with normal daily tasks of a growing number of individuals. Such neurodegenerative diseases are often accompanied with progressive brain…