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The segmentation of kidney layer structures, including cortex, outer stripe, inner stripe, and inner medulla within human kidney whole slide images (WSI) plays an essential role in automated image analysis in renal pathology. However, the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Muhao Liu , Chenyang Qi , Shunxing Bao , Quan Liu , Ruining Deng , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

The process of collecting blood from donors and making it available for transfusion requires a complex series of operations involving multiple actors and resources at each step. Ensuring hospitals receive adequate and safe blood for…

The allocation of scarce donor organs constitutes one of the most consequential algorithmic challenges in healthcare. While the field is rapidly transitioning from rigid, rule-based systems to machine learning and data-driven optimization,…

Machine Learning · Computer Science 2026-05-27 Ioannis Anagnostides , Itai Zilberstein , Zachary W. Sollie , Arman Kilic , Tuomas Sandholm

Heart transplantation is a viable path for patients suffering from advanced heart failure, but this lifesaving option is severely limited due to donor shortage. Although the current allocation policy was recently revised in 2018, a major…

Machine Learning · Computer Science 2025-12-16 Ioannis Anagnostides , Zachary W. Sollie , Arman Kilic , Tuomas Sandholm

Nested sampling (NS) has emerged as a powerful tool for exploring thermodynamic properties in materials science. However, its efficiency is often hindered by the limitations of Markov chain Monte Carlo (MCMC) sampling. In strongly…

Statistical Mechanics · Physics 2025-07-31 Nico Unglert , Livia Bartók Pártay , Georg K. H. Madsen

This paper proposes a causal decomposition framework for settings in which an initial regime randomization influences the timing of a treatment duration. The initial randomization and treatment affect in turn a duration outcome of interest.…

Econometrics · Economics 2022-05-24 Stephen Kastoryano

Embedding methods have become popular due to their scalability on link prediction and/or triple classification tasks on Knowledge Graphs. Embedding models are trained relying on both positive and negative samples of triples. However, in the…

Machine Learning · Computer Science 2025-08-08 Claudia d'Amato , Ivan Diliso , Nicola Fanizzi , Zafar Saeed

Kidney stone disease ranks among the most prevalent conditions in urology, and understanding the composition of these stones is essential for creating personalized treatment plans and preventing recurrence. Current methods for analyzing…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Changmiao Wang , Songqi Zhang , Yongquan Zhang , Yifei Wang , Liya Liu , Nannan Li , Xingzhi Li , Jiexin Pan , Yi Jiang , Xiang Wan , Hai Wang , Ahmed Elazab

Drug repositioning offers an effective solution to drug discovery, saving both time and resources by finding new indications for existing drugs. Typically, a drug takes effect via its protein targets in the cell. As a result, it is…

Quantitative Methods · Quantitative Biology 2018-11-26 Maryam Lotfi Shahreza , Nasser Ghadiri , Seyed Rasul Mossavi , Jaleh Varshosaz , James Green

In this review we make the statement that hybrid models in oncology are required as a mean for enhanced data integration. In the context of systems oncology, experimental and clinical data need to be at the heart of the models developments…

Quantitative Methods · Quantitative Biology 2019-01-18 Angélique Stéphanou , Pascal Ballet , Gibin Powathil

In practise, it is often desirable to provide the decision-maker with a rich set of diverse solutions of decent quality instead of just a single solution. In this paper we study evolutionary diversity optimization for the knapsack problem…

Neural and Evolutionary Computing · Computer Science 2021-04-28 Jakob Bossek , Aneta Neumann , Frank Neumann

Motivated by genome-wide association studies, we consider a standard linear model with one additional random effect in situations where many predictors have been collected on the same subjects and each predictor is analyzed separately.…

Applications · Statistics 2013-04-24 Matti Pirinen , Peter Donnelly , Chris C. A. Spencer

Chronic Kidney Disease (CKD) constitutes a major global medical burden, marked by the gradual deterioration of renal function, which results in the impaired clearance of metabolic waste and disturbances in systemic fluid homeostasis. Owing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Anas Bin Ayub , Nilima Sultana Niha , Md. Zahurul Haque

Chronic kidney disease (CKD) is a growing global health concern, necessitating precise and efficient image analysis to aid diagnosis and treatment planning. Automated segmentation of kidney pathology images plays a central role in…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Mingyang Zhu , Yuqiu Liang , Jiacheng Wang

Diamond relay channel model, as a basic transmission model, has recently been attracting considerable attention in wireless Ad Hoc networks. Node cooperation and opportunistic scheduling scheme are two important techniques to improve the…

Information Theory · Computer Science 2009-07-13 Qing Wang , Pingyi Fan , Khaled Ben Letaief

This is the first report, to our knowledge, on a systematic method for constructing a large scale kinetic metabolic model with incomplete information on kinetic parametersr, and its initial application to the modeling of central metabolism…

Molecular Networks · Quantitative Biology 2008-08-05 P. Ao , L. W. Lee , Me Lidstrom , L. Yin , X. M. Zhu

Deep-learning techniques, particularly the transformer model, have shown great potential in enhancing the prediction performance of longitudinal health records. While previous methods have mainly focused on fixed-time risk prediction,…

Machine Learning · Computer Science 2024-05-03 Moshe Zisser , Dvir Aran

Precision medicine involves developing individualized treatment regimes (ITRs) which allow for treatment decisions to be tailored to patient characteristics. Naturally, the identification of the optimal regime, that is, the rule which…

Methodology · Statistics 2025-09-30 Misha Dolmatov , Erica E. M. Moodie , David A. Stephens , Dipankar Bandyopadhyay

This contribution presents a deep learning method for the extraction and fusion of information relating to kidney stone fragments acquired from different viewpoints of the endoscope. Surface and section fragment images are jointly used…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Elias Villalvazo-Avila , Francisco Lopez-Tiro , Jonathan El-Beze , Jacques Hubert , Miguel Gonzalez-Mendoza , Gilberto Ochoa-Ruiz , Christian Daul

Chronic kidney disease (CKD) is a global health challenge characterized by progressive kidney function decline, often culminating in end-stage kidney disease (ESKD) and increased mortality. To address the limitations such as the extended…

Methodology · Statistics 2025-04-11 Tuo Wang , Yu Du