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Permutation tests are widely used in statistics, providing a finite-sample guarantee on the type I error rate whenever the distribution of the samples under the null hypothesis is invariant to some rearrangement. Despite its increasing…

Statistics Theory · Mathematics 2022-05-26 Ilmun Kim , Sivaraman Balakrishnan , Larry Wasserman

Permutation tests date back nearly a century to Fisher's randomized experiments, and remain an immensely popular statistical tool, used for testing hypotheses of independence between variables and other common inferential questions. Much of…

Methodology · Statistics 2022-12-05 Aaditya Ramdas , Rina Foygel Barber , Emmanuel J. Candes , Ryan J. Tibshirani

Permutation tests are a distribution free way of performing hypothesis tests. These tests rely on the condition that the observed data are exchangeable among the groups being tested under the null hypothesis. This assumption is easily…

Methodology · Statistics 2017-12-14 Daniell Toth

In this paper, we investigate local permutation tests for testing conditional independence between two random vectors $X$ and $Y$ given $Z$. The local permutation test determines the significance of a test statistic by locally shuffling…

Statistics Theory · Mathematics 2022-01-07 Ilmun Kim , Matey Neykov , Sivaraman Balakrishnan , Larry Wasserman

In nonparametric independence testing, we observe i.i.d.\ data $\{(X_i,Y_i)\}_{i=1}^n$, where $X \in \mathcal{X}, Y \in \mathcal{Y}$ lie in any general spaces, and we wish to test the null that $X$ is independent of $Y$. Modern test…

Methodology · Statistics 2022-12-20 Shubhanshu Shekhar , Ilmun Kim , Aaditya Ramdas

The Hilbert--Schmidt Independence Criterion (HSIC) is a popular measure of the dependency between two random variables. The statistic dHSIC is an extension of HSIC that can be used to test joint independence of $d$ random variables. Such…

Statistics Theory · Mathematics 2020-05-15 David Rindt , Dino Sejdinovic , David Steinsaltz

Non-parametric two-sample tests based on energy distance or maximum mean discrepancy are widely used statistical tests for comparing multivariate data from two populations. While these tests enjoy desirable statistical properties, their…

Computation · Statistics 2024-06-11 Elias Chaibub Neto

We study the problem of independence testing given independent and identically distributed pairs taking values in a $\sigma$-finite, separable measure space. Defining a natural measure of dependence $D(f)$ as the squared $L^2$-distance…

Statistics Theory · Mathematics 2020-11-09 Thomas B. Berrett , Ioannis Kontoyiannis , Richard J. Samworth

We present the $U$-Statistic Permutation (USP) test of independence in the context of discrete data displayed in a contingency table. Either Pearson's chi-squared test of independence, or the $G$-test, are typically used for this task, but…

Methodology · Statistics 2022-01-19 Thomas B. Berrett , Richard J. Samworth

We consider the problem of testing whether pairs of univariate random variables are associated. Few tests of independence exist that are consistent against all dependent alternatives and are distribution free. We propose novel tests that…

Methodology · Statistics 2014-12-09 Ruth Heller , Yair Heller , Shachar Kaufman , Malka Gorfine

Given observations from a stationary time series, permutation tests allow one to construct exactly level $\alpha$ tests under the null hypothesis of an i.i.d. (or, more generally, exchangeable) distribution. On the other hand, when the null…

Statistics Theory · Mathematics 2020-09-09 Joseph P. Romano , Marius A. Tirlea

Researchers in genetics and other life sciences commonly use permutation tests to evaluate differences between groups. Permutation tests have desirable properties, including exactness if data are exchangeable, and are applicable even when…

Computation · Statistics 2018-11-01 Brian Segal , Thomas Braun , Michael Elliott , Hui Jiang

Classical two-sample permutation tests for equality of distributions have exact size in finite samples, but they fail to control size for testing equality of parameters that summarize each distribution. This paper proposes permutation tests…

Econometrics · Economics 2022-04-22 Marinho Bertanha , EunYi Chung

Permutation testing in linear models, where the number of nuisance coefficients is smaller than the sample size, is a well-studied topic. The common approach of such tests is to permute residuals after regressing on the nuisance covariates.…

Methodology · Statistics 2020-10-09 Jesse Hemerik , Magne Thoresen , Livio Finos

In group sequential designs, where several data looks are conducted for early stopping, we generally assume the vector of test statistics from the sequential analyses follows (at least approximately or asymptotially) a multivariate normal…

Statistics Theory · Mathematics 2024-04-22 Long-Hao Xu , Tobias Mütze , Frank Konietschke , Tim Friede

We present a general approach to constructing permutation tests that are both exact for the null hypothesis of equality of distributions and asymptotically correct for testing equality of parameters of distributions while allowing the…

Statistics Theory · Mathematics 2021-07-12 Colin B. Fogarty

In large scale genetic association studies, a primary aim is to test for association between genetic variants and a disease outcome. The variants of interest are often rare, and appear with low frequency among subjects. In this situation,…

Methodology · Statistics 2017-12-20 Arjun Sondhi , Kenneth Martin Rice

Testing for association or dependence between pairs of random variables is a fundamental problem in statistics. In some applications, data are subject to selection bias that causes dependence between observations even when it is absent from…

Methodology · Statistics 2020-10-13 Yaniv Tenzer , Micha Mandel , Or Zuk

{\bf Motivation:} Permutation-based gene set tests are standard approaches for testing relationshi ps between collections of related genes and an outcome of interest in high throughput expression analyses. Using $M$ random permutations, one…

Computation · Statistics 2014-05-07 Jessica L. Larson , Art B. Owen

We propose a general new method, the conditional permutation test, for testing the conditional independence of variables $X$ and $Y$ given a potentially high-dimensional random vector $Z$ that may contain confounding factors. The proposed…

Methodology · Statistics 2019-05-08 Thomas B. Berrett , Yi Wang , Rina Foygel Barber , Richard J. Samworth
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