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Current multi-instance learning algorithms for pathology image analysis often require a substantial number of Whole Slide Images for effective training but exhibit suboptimal performance in scenarios with limited learning data. In clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Linhao Qu , Dingkang Yang , Dan Huang , Qinhao Guo , Rongkui Luo , Shaoting Zhang , Xiaosong Wang

In this paper, we address the challenge of few-shot classification in histopathology whole slide images (WSIs) by utilizing foundational vision-language models (VLMs) and slide-level prompt learning. Given the gigapixel scale of WSIs,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Devavrat Tomar , Guillaume Vray , Dwarikanath Mahapatra , Sudipta Roy , Jean-Philippe Thiran , Behzad Bozorgtabar

Multiple instance learning (MIL) has become a standard paradigm for the weakly supervised classification of whole slide images (WSIs). However, this paradigm relies on using a large number of labeled WSIs for training. The lack of training…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Minghao Han , Linhao Qu , Dingkang Yang , Xukun Zhang , Xiaoying Wang , Lihua Zhang

This paper introduces the novel concept of few-shot weakly supervised learning for pathology Whole Slide Image (WSI) classification, denoted as FSWC. A solution is proposed based on prompt learning and the utilization of a large language…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Linhao Qu , Xiaoyuan Luo , Kexue Fu , Manning Wang , Zhijian Song

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

Few-shot learning has been successfully applied to medical image classification as only very few medical examples are available for training. Due to the challenging problem of limited number of annotated medical images, image…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Zhenwei Wang , Qiule Sun , Bingbing Zhang , Pengfei Wang , Jianxin Zhang , Qiang Zhang

While Vision-Language Models (VLMs) have achieved notable progress in computational pathology (CPath), the gigapixel scale and spatial heterogeneity of Whole Slide Images (WSIs) continue to pose challenges for multimodal understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Fengchun Liu , Songhan Jiang , Linghan Cai , Ziyue Wang , Yongbing Zhang

Few-shot, fine-grained classification in computer vision poses significant challenges due to the need to differentiate subtle class distinctions with limited data. This paper presents a novel method that enhances the Contrastive…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Eric Brouwer , Jan Erik van Woerden , Gertjan Burghouts , Matias Valdenegro-Toro , Marco Zullich

Prompt learning has demonstrated impressive efficacy in the fine-tuning of multimodal large models to a wide range of downstream tasks. Nonetheless, applying existing prompt learning methods for the diagnosis of neurological disorder still…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Liang Peng , Songyue Cai , Zongqian Wu , Huifang Shang , Xiaofeng Zhu , Xiaoxiao Li

Whole Slide Images (WSIs) are giga-pixel in scale and are typically partitioned into small instances in WSI classification pipelines for computational feasibility. However, obtaining extensive instance level annotations is costly, making…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jayanie Bogahawatte , Sachith Seneviratne , Saman Halgamuge

The Contrastive Language-Image Pretraining (CLIP) model has been widely used in various downstream vision tasks. The few-shot learning paradigm has been widely adopted to augment its capacity for these tasks. However, current paradigms may…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Jintao Rong , Hao Chen , Linlin Ou , Tianxiao Chen , Xinyi Yu , Yifan Liu

Few-shot learning presents a critical solution for cancer diagnosis in computational pathology (CPath), addressing fundamental limitations in data availability, particularly the scarcity of expert annotations and patient privacy…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Zhengrui Guo , Conghao Xiong , Jiabo Ma , Qichen Sun , Lishuang Feng , Jinzhuo Wang , Hao Chen

Automated generation of diagnostic pathology reports directly from whole slide images (WSIs) is an emerging direction in computational pathology. Translating high-resolution tissue patterns into clinically coherent text remains difficult…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Noorul Wahab , Nasir Rajpoot

Few-shot learning is a challenging problem since only a few examples are provided to recognize a new class. Several recent studies exploit additional semantic information, e.g. text embeddings of class names, to address the issue of rare…

Computer Vision and Pattern Recognition · Computer Science 2023-03-27 Wentao Chen , Chenyang Si , Zhang Zhang , Liang Wang , Zilei Wang , Tieniu Tan

Few-shot adaptation of vision-language models (VLMs) like CLIP typically relies on learning textual prompts matched to global image embeddings. Recent works extend this paradigm by incorporating local image-text alignment to capture…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Deniz Kizaroğlu , Ülku Tuncer Küçüktas , Emre Çakmakyurdu , Alptekin Temizel

Remote sensing applications increasingly rely on deep learning for scene classification. However, their performance is often constrained by the scarcity of labeled data and the high cost of annotation across diverse geographic and sensor…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Ivica Dimitrovski , Vlatko Spasev , Ivan Kitanovski

Pre-trained Vision-Language Models (VLMs), like CLIP, exhibit strong generalization ability to downstream tasks but struggle in few-shot scenarios. Existing prompting techniques primarily focus on global text and image representations, yet…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Xin Liu , Jiamin Wu , and Wenfei Yang , Xu Zhou , Tianzhu Zhang

Most advances in medical image recognition supporting clinical auxiliary diagnosis meet challenges due to the low-resource situation in the medical field, where annotations are highly expensive and professional. This low-resource problem…

Computer Vision and Pattern Recognition · Computer Science 2024-02-07 Fudan Zheng , Jindong Cao , Weijiang Yu , Zhiguang Chen , Nong Xiao , Yutong Lu

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). Existing approaches typically rely on frozen pre-trained models to extract instance features, neglecting the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Yi Lin , Zhengjie Zhu , Kwang-Ting Cheng , Hao Chen

As powerful pre-trained vision-language models (VLMs) like CLIP gain prominence, numerous studies have attempted to combine VLMs for downstream tasks. Among these, prompt learning has been validated as an effective method for adapting to…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Yu Du , Tong Niu , Rong Zhao
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