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We demonstrate a simple and effective automated method for the segmentation of glomeruli from large (~1 gigapixel) histopathological whole-slide images (WSIs) of thin renal tissue sections and biopsies, using an adaptation of the well-known…

Tissues and Organs · Quantitative Biology 2017-09-21 Olivier Simon , Rabi Yacoub , Sanjay Jain , Pinaki Sarder

Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Abdul Basit , Ashir Rashid , Muhammad Abdullah Hanif , Muhammad Shafique

Colorectal cancer (CRC) is the third cause of cancer death worldwide. Currently, the standard approach to reduce CRC-related mortality is to perform regular screening in search for polyps and colonoscopy is the screening tool of choice. The…

Computer Vision and Pattern Recognition · Computer Science 2016-12-05 David Vázquez , Jorge Bernal , F. Javier Sánchez , Gloria Fernández-Esparrach , Antonio M. López , Adriana Romero , Michal Drozdzal , Aaron Courville

The pancreatic disease taxonomy includes ten types of masses (tumors or cysts)[20,8]. Previous work focuses on developing segmentation or classification methods only for certain mass types. Differential diagnosis of all mass types is…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Tianyi Zhao , Kai Cao , Jiawen Yao , Isabella Nogues , Le Lu , Lingyun Huang , Jing Xiao , Zhaozheng Yin , Ling Zhang

Background: The kidney exchange problem (KEP) addresses the matching of patients in need for a replacement organ with compatible living donors. Ideally many medical institutions should participate in a matching program to increase the…

Cryptography and Security · Computer Science 2022-04-22 Timm Birka , Kay Hamacher , Tobias Kussel , Helen Möllering , Thomas Schneider

Organ and cancer segmentation in abdomen Computed Tomography (CT) scans is the prerequisite for precise cancer diagnosis and treatment. Most existing benchmarks and algorithms are tailored to specific cancer types, limiting their ability to…

Image and Video Processing · Electrical Eng. & Systems 2024-08-23 Jun Ma , Yao Zhang , Song Gu , Cheng Ge , Ershuai Wang , Qin Zhou , Ziyan Huang , Pengju Lyu , Jian He , Bo Wang

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Automatic analysis of colonoscopy images has been an active field of research motivated by the importance of early detection of precancerous polyps. However, detecting polyps during the live examination can be challenging due to various…

Parkinsons Disease (PD) is a progressive neurological disorder that primarily affects motor functions and can lead to mild cognitive impairment (MCI) and dementia in its advanced stages. With approximately 10 million people diagnosed…

Image and Video Processing · Electrical Eng. & Systems 2025-05-02 Abu Saleh Musa Miah , taro Suzuki , Jungpil Shin

Cervical cancer is one of the deadliest cancers affecting women globally. Cervical intraepithelial neoplasia (CIN) assessment using histopathological examination of cervical biopsy slides is subject to interobserver variability. Automated…

Image and Video Processing · Electrical Eng. & Systems 2020-07-23 Sudhir Sornapudi , R. Joe Stanley , William V. Stoecker , Rodney Long , Zhiyun Xue , Rosemary Zuna , Shelliane R. Frazier , Sameer Antani

Accurate detection of diseased glomeruli is fundamental to progress in renal pathology and underpins the delivery of reliable clinical diagnoses. Although recent advances in computer vision have produced increasingly sophisticated detection…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Tianyu Shi , Xinzi He , Kenji Ikemura , Mert R. Sabuncu , Yihe Yang , Ruining Deng

Analysis of histopathology slides is a critical step for many diagnoses, and in particular in oncology where it defines the gold standard. In the case of digital histopathological analysis, highly trained pathologists must review vast…

Computer Vision and Pattern Recognition · Computer Science 2020-02-21 Pierre Courtiol , Eric W. Tramel , Marc Sanselme , Gilles Wainrib

Goal: Squamous cell carcinoma of cervix is one of the most prevalent cancer worldwide in females. Traditionally, the most indispensable diagnosis of cervix squamous carcinoma is histopathological assessment which is achieved under…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Ye Tian , Li Yang , Wei Wang , Jing Zhang , Qing Tang , Mili Ji , Yang Yu , Yu Li , Hong Yang , Airong Qian

Multi-instance learning (MIL) is widely used in the computer-aided interpretation of pathological Whole Slide Images (WSIs) to solve the lack of pixel-wise or patch-wise annotations. Often, this approach directly applies "natural image…

The Vision Foundation Model has recently gained attention in medical image analysis. Its zero-shot learning capabilities accelerate AI deployment and enhance the generalizability of clinical applications. However, segmenting pathological…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Can Cui , Ruining Deng , Junlin Guo , Quan Liu , Tianyuan Yao , Haichun Yang , Yuankai Huo

Pancreatic cancer will soon be the second leading cause of cancer-related death in Western society. Imaging techniques such as CT, MRI and ultrasound typically help providing the initial diagnosis, but histopathological assessment is still…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Pierpaolo Vendittelli , Esther M. M. Smeets , Geert Litjens

Efficiently quantifying renal structures can provide distinct spatial context and facilitate biomarker discovery for kidney morphology. However, the development and evaluation of the transformer model to segment the renal cortex, medulla,…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Xin Yu , Yucheng Tang , Yinchi Zhou , Riqiang Gao , Qi Yang , Ho Hin Lee , Thomas Li , Shunxing Bao , Yuankai Huo , Zhoubing Xu , Thomas A. Lasko , Richard G. Abramson , Bennett A. Landman

Liver fibrosis represents the accumulation of excessive extracellular matrix caused by sustained hepatic injury. It disrupts normal lobular architecture and function, increasing the chances of cirrhosis and liver failure. Precise staging of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-01 Yang Zhou , Kunhao Yuan , Ye Wei , Jishizhan Chen

Liver fibrosis poses a substantial challenge in clinical practice, emphasizing the necessity for precise liver segmentation and accurate disease staging. Based on the CARE Liver 2025 Track 4 Challenge, this study introduces a multi-task…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Boya Wang , Ruizhe Li , Chao Chen , Xin Chen

There has been a significant increase from 2010 to 2016 in the number of people suffering from spine problems. The automatic image segmentation of the spine obtained from a computed tomography (CT) image is important for diagnosing spine…

Computer Vision and Pattern Recognition · Computer Science 2017-12-06 Malinda Vania , Dawit Mureja , Deukhee Lee
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