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Alzheimer's disease (AD) and sleep disorders exhibit a close association, where disruptions in sleep patterns often precede the onset of Mild Cognitive Impairment (MCI) and early-stage AD. This study delves into the potential of utilizing…
Over the past decade, machine learning techniques especially predictive modeling and pattern recognition in biomedical sciences from drug delivery system to medical imaging has become one of the important methods which are assisting…
People with Parkinson's disease must be regularly monitored by their physician to observe how the disease is progressing and potentially adjust treatment plans to mitigate the symptoms. Monitoring the progression of the disease through a…
Alzheimer's disease (AD) is one of the most common public health issues the world is facing today. This disease has a high prevalence primarily in the elderly accompanying memory loss and cognitive decline. AD detection is a challenging…
Alzheimer's Disease (AD) is a neurodegenerative disease affecting millions of individuals across the globe. As the prevalence of this disease continues to rise, early diagnosis is crucial to improve clinical outcomes. Neural networks,…
We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This…
Parkinson's Disease (PD) diagnosis remains challenging. This study applies Convolutional Kolmogorov-Arnold Networks (ConvKANs), integrating learnable spline-based activation functions into convolutional layers, for PD classification using…
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that progressively destroys memory and other cognitive domains of the brain. While effective therapeutic management of AD is still in development, it seems reasonable to…
Parkinson's disease (PD) is a progressive neurological disorder that impairs movement control, leading to symptoms such as tremors, stiffness, and bradykinesia. Many researchers analyzing handwriting data for PD detection typically rely on…
Alzheimers Disease AD is an acute neuro disease that degenerates the brain cells and thus leads to memory loss progressively. It is a fatal brain disease that mostly affects the elderly. It steers the decline of cognitive and biological…
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, structural brain changes, and genetic predispositions. This study leverages machine-learning and statistical techniques to investigate…
Early diagnosis, playing an important role in preventing progress and treating the Alzheimer's disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…
Deep learning models have shown strong performance in classifying Alzheimer's disease (AD) from R2* maps, but their decision-making remains opaque, raising concerns about interpretability. Previous studies suggest biases in model decisions,…
Introduction- This paper mainly describes a way to detect with high accuracy patients with early-stage Alzheimer's disease (ES-AD) versus healthy control (HC) subjects, from datasets built with handwriting and drawing task records. Method-…
Parkinson's Disease (PD) is one of the most prevalent neurodegenerative diseases that affects tens of millions of Americans. PD is highly progressive and heterogeneous. Quite a few studies have been conducted in recent years on predictive…
Late-life depression (LLD) is a highly prevalent mood disorder occurring in older adults and is frequently accompanied by cognitive impairment (CI). Studies have shown that LLD may increase the risk of Alzheimer's disease (AD). However, the…
Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…
Serious games have proven to be effective tools for screening cognitive impairments and supporting diagnosis in patients with neurodegenerative diseases like Alzheimer's and Parkinson's. They also offer cognitive training benefits.…
Parkinson's disease (PD) is a chronic neurodegenerative disease. It shows multiple motor symptoms such as tremor, bradykinesia, postural instability, freezing of gait (FoG). PD is currently diagnosed clinically through physical exam by…
Neuroimaging biomarkers that distinguish between typical brain aging and Alzheimer's disease (AD) are valuable for determining how much each contributes to cognitive decline. Machine learning models can derive multi-variate brain change…