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Obtaining high-quality labels for large datasets is expensive, requiring massive annotations from human experts. While AI models offer a cost-effective alternative by predicting labels, their label quality is compromised by the unavoidable…

Machine Learning · Computer Science 2026-02-17 Huipeng Huang , Wenbo Liao , Huajun Xi , Hao Zeng , Mengchen Zhao , Hongxin Wei

Methods to quantify uncertainty in predictions from arbitrary models are in demand in high-stakes domains like medicine and finance. Conformal prediction has emerged as a popular method for producing a set of predictions with specified…

Machine Learning · Computer Science 2025-03-19 Jessica Hullman , Yifan Wu , Dawei Xie , Ziyang Guo , Andrew Gelman

Modern deep learning based classifiers show very high accuracy on test data but this does not provide sufficient guarantees for safe deployment, especially in high-stake AI applications such as medical diagnosis. Usually, predictions are…

Machine Learning · Computer Science 2022-05-09 David Stutz , Krishnamurthy , Dvijotham , Ali Taylan Cemgil , Arnaud Doucet

Unlike the typical classification setting where each instance is associated with a single class, in multi-label learning each instance is associated with multiple classes simultaneously. Therefore the learning task in this setting is to…

Machine Learning · Computer Science 2022-11-30 Harris Papadopoulos

Conformal Prediction (CP) is a principled framework for quantifying uncertainty in blackbox learning models, by constructing prediction sets with finite-sample coverage guarantees. Traditional approaches rely on scalar nonconformity scores,…

Machine Learning · Statistics 2025-05-07 Gauthier Thurin , Kimia Nadjahi , Claire Boyer

Deep learning based cervical cancer classification can potentially increase access to screening in low-resource regions. However, deep learning models are often overconfident and do not reliably reflect diagnostic uncertainty. Moreover,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-15 Misgina Tsighe Hagos , Antti Suutala , Dmitrii Bychkov , Hakan Kücükel , Joar von Bahr , Milda Poceviciute , Johan Lundin , Nina Linder , Claes Lundström

Conformal Prediction is a framework that produces prediction intervals based on the output from a machine learning algorithm. In this paper we explore the case when training data is made up of multiple parts available in different sources…

Machine Learning · Statistics 2019-08-16 Ola Spjuth , Robin Carrión Brännström , Lars Carlsson , Niharika Gauraha

Quantifying differences between probability distributions is fundamental to statistics and machine learning, primarily for comparing statistical uncertainty. In contrast, epistemic uncertainty -- due to incomplete knowledge -- requires…

Machine Learning · Statistics 2026-05-13 Siu Lun Chau , Michele Caprio , Krikamol Muandet

Uncertainty estimation is critical in high-stakes machine learning applications. One effective way to estimate uncertainty is conformal prediction, which can provide predictive inference with statistical coverage guarantees. We present a…

Machine Learning · Computer Science 2023-11-03 Nathaniel Diamant , Ehsan Hajiramezanali , Tommaso Biancalani , Gabriele Scalia

Conformal prediction provides distribution-free coverage guarantees, but in many-class classification it may still under-cover specific classes or subpopulations, preventing safe deployment in high-stakes applications. We propose Cluster…

Machine Learning · Computer Science 2026-05-26 Tomer Lavi , Bracha Shapira , Nadav Rappoport

Handling incomplete and heterogeneous data remains a central challenge in real-world machine learning, where missing values may follow complex mechanisms (MCAR, MAR, MNAR) and features can be of mixed types (numerical and categorical).…

Machine Learning · Computer Science 2025-07-30 Youran Zhou , Mohamed Reda Bouadjenek , Jonathan Wells , Sunil Aryal

In many complex applications, data heterogeneity and homogeneity exist simultaneously. Ignoring either one will result in incorrect statistical inference. In addition, coping with complex data that are non-Euclidean becomes more common. To…

Methodology · Statistics 2021-05-28 Zixuan Han , Tao Li , Jinhong You

The safe integration of machine learning modules in decision-making processes hinges on their ability to quantify uncertainty. A popular technique to achieve this goal is conformal prediction (CP), which transforms an arbitrary base…

Machine Learning · Computer Science 2024-01-23 Matteo Zecchin , Sangwoo Park , Osvaldo Simeone , Fredrik Hellström

This paper introduces a conformal inference method to evaluate uncertainty in classification by generating prediction sets with valid coverage conditional on adaptively chosen features. These features are carefully selected to reflect…

Machine Learning · Statistics 2024-10-31 Yanfei Zhou , Matteo Sesia

Conformal prediction is a model-agnostic approach to generating prediction sets that cover the true class with a high probability. Although its prediction set size is expected to capture aleatoric uncertainty, there is a lack of evidence…

Machine Learning · Computer Science 2025-11-24 Misgina Tsighe Hagos , Claes Lundström

In regression problems where there is no known true underlying model, conformal prediction methods enable prediction intervals to be constructed without any assumptions on the distribution of the underlying data, except that the training…

Methodology · Statistics 2023-01-31 Wenyu Chen , Kelli-Jean Chun , Rina Foygel Barber

The paper presents an application of Conformal Predictors to a chemoinformatics problem of identifying activities of chemical compounds. The paper addresses some specific challenges of this domain: a large number of compounds (training…

Machine Learning · Computer Science 2016-03-16 Paolo Toccacheli , Ilia Nouretdinov , Alexander Gammerman

Consider an edge computing setting in which a user submits queries for the solution of a linear system to an edge processor, which is subject to time-varying computing availability. The edge processor applies a probabilistic linear solver…

Machine Learning · Statistics 2025-04-30 Qiushuo Hou , Sangwoo Park , Matteo Zecchin , Yunlong Cai , Guanding Yu , Osvaldo Simeone

Predictive Coding (PC) is a theoretical framework in cognitive science suggesting that the human brain processes cognition through spatiotemporal prediction of the visual world. Existing studies have developed spatiotemporal prediction…

Neural and Evolutionary Computing · Computer Science 2024-05-07 Kaiyuan Chen , Xingzhuo Guo , Yu Zhang , Jianmin Wang , Mingsheng Long

Most machine learning-based image segmentation models produce pixel-wise confidence scores that represent the model's predicted probability for each class label at every pixel. While this information can be particularly valuable in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Bruno Viti , Elias Karabelas , Martin Holler