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The histopathological images contain a huge amount of information, which can make diagnosis an extremely timeconsuming and tedious task. In this study, we developed a completely automated system to detect regions of interest (ROIs) in whole…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Mohammed Lamine Benomar , Nesma Settouti , Eric Debreuve , Xavier Descombes , Damien Ambrosetti

Every year millions of people die due to disease of Cancer. Due to its invasive nature it is very complex to cure even in primary stages. Hence, only method to survive this disease completely is via forecasting by analyzing the early…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Shivam Singh , Stuti Pathak

Manually annotating nuclei from the gigapixel Hematoxylin and Eosin (H&E)-stained Whole Slide Images (WSIs) is a laborious and costly task, meaning automated algorithms for cell nuclei instance segmentation and classification could…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 João D. Nunes , Diana Montezuma , Domingos Oliveira , Tania Pereira , Jaime S. Cardoso

Deep-learning techniques have been used widely to alleviate the labour-intensive and time-consuming manual annotation required for pixel-level tissue characterization. Our previous study introduced an efficient single dynamic network -…

Image and Video Processing · Electrical Eng. & Systems 2023-05-25 Haoju Leng , Ruining Deng , Zuhayr Asad , R. Michael Womick , Haichun Yang , Lipeng Wan , Yuankai Huo

Digital pathology, augmented by artificial intelligence (AI), holds significant promise for improving the workflow of pathologists. However, challenges such as the labor-intensive annotation of whole slide images (WSIs), high computational…

Image and Video Processing · Electrical Eng. & Systems 2025-04-18 Walid Rehamnia , Alexandra Getmanskaya , Evgeniy Vasilyev , Vadim Turlapov

Skin cancer (SC) stands out as one of the most life-threatening forms of cancer, with its danger amplified if not diagnosed and treated promptly. Early intervention is critical, as it allows for more effective treatment approaches. In…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Ramin Mousa , Saeed Chamani , Mohammad Morsali , Mohammad Kazzazi , Parsa Hatami , Soroush Sarabi

Segmentation is one of the most significant steps in image processing. Segmenting an image is a technique that makes it possible to separate a digital image into various areas based on the different characteristics of pixels in the image.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Sina Derakhshandeh , Ali Mahloojifar

Objective. Limited access to breast cancer diagnosis globally leads to delayed treatment. Ultrasound, an effective yet underutilized method, requires specialized training for sonographers, which hinders its widespread use. Approach. Volume…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Donya Khaledyan , Thomas J. Marini , Avice OConnell , Steven Meng , Jonah Kan , Galen Brennan , Yu Zhao , Timothy M. Baran , Kevin J. Parker

Volumetric cell segmentation in fluorescence microscopy images is important to study a wide variety of cellular processes. Applications range from the analysis of cancer cells to behavioral studies of cells in the embryonic stage. Like in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Royden Wagner , Karl Rohr

Accurate nuclei segmentation in histopathological images is crucial for cancer diagnosis. Automating this process offers valuable support to clinical experts, as manual annotation is time-consuming and prone to human errors. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Ayush Roy , Payel Pramanik , Dmitrii Kaplun , Sergei Antonov , Ram Sarkar

Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

Histopathology has played an essential role in cancer diagnosis. With the rapid advances in convolutional neural networks (CNN). Various CNN-based automated pathological image segmentation approaches have been developed in computer-assisted…

Image and Video Processing · Electrical Eng. & Systems 2021-09-23 Cam Nguyen , Zuhayr Asad , Yuankai Huo

In digital pathology, cell detection and classification are often prerequisites to quantify cell abundance and explore tissue spatial heterogeneity. However, these tasks are particularly challenging for multiplex immunohistochemistry (mIHC)…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Yeman Brhane Hagos , Priya Lakshmi Narayanan , Ayse U. Akarca , Teresa Marafioti , Yinyin Yuan

In-vivo optical microscopy is advancing into routine clinical practice for non-invasively guiding diagnosis and treatment of cancer and other diseases, and thus beginning to reduce the need for traditional biopsy. However, reading and…

Image and Video Processing · Electrical Eng. & Systems 2020-01-07 Kivanc Kose , Alican Bozkurt , Christi Alessi-Fox , Melissa Gill , Caterina Longo , Giovanni Pellacani , Jennifer Dy , Dana H. Brooks , Milind Rajadhyaksha

Breast cancer is the most diagnosed cancer and the most predominant cause of death in women worldwide. Imaging techniques such as the breast cancer pathology helps in the diagnosis and monitoring of the disease. However identification of…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Francisco Perdigon Romero , An Tang , Samuel Kadoury

Supervised deep learning methods have achieved considerable success in medical image analysis, owing to the availability of large-scale and well-annotated datasets. However, creating such datasets for whole slide images (WSIs) in…

Computer Vision and Pattern Recognition · Computer Science 2024-06-10 Hao Wang , Euijoon Ahn , Jinman Kim

Digital gigapixel whole slide image (WSI) is widely used in clinical diagnosis, and automated WSI analysis is key for computer-aided diagnosis. Currently, analyzing the integrated descriptor of probabilities or feature maps from massive…

Computer Vision and Pattern Recognition · Computer Science 2022-06-06 Ziquan Wei , Shenghua Cheng , Junbo Hu , Li Chen , Shaoqun Zeng , Xiuli Liu

Tissue segmentation is an important pre-requisite for efficient and accurate diagnostics in digital pathology. However, it is well known that whole-slide scanners can fail in detecting all tissue regions, for example due to the tissue type,…

Computer Vision and Pattern Recognition · Computer Science 2017-04-04 Péter Bándi , Rob van de Loo , Milad Intezar , Daan Geijs , Francesco Ciompi , Bram van Ginneken , Jeroen van der Laak , Geert Litjens

Medical image segmentation is crucial for disease diagnosis and monitoring. Though effective, the current segmentation networks such as UNet struggle with capturing long-range features. More accurate models such as TransUNet, Swin-UNet, and…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Khaled Alrfou , Tian Zhao

Sickle cell anemia, which is characterized by abnormal erythrocyte morphology, can be detected using microscopic images. Computational techniques in medicine enhance the diagnosis and treatment efficiency. However, many computational…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Victor Júnio Alcântara Cardoso , Rodrigo Moreira , João Fernando Mari , Larissa Ferreira Rodrigues Moreira