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Electronic Health Records (EHRs) are pivotal in clinical practices, yet their retrieval remains a challenge mainly due to semantic gap issues. Recent advancements in dense retrieval offer promising solutions but existing models, both…

Information Retrieval · Computer Science 2025-07-25 Zhengyun Zhao , Huaiyuan Ying , Yue Zhong , Sheng Yu

Electronic Health Records (EHR) store clinical documentation as base64 encoded attachments in FHIR DocumentReference resources, which makes semantic question answering difficult. Traditional vector database methods often miss nuanced…

Computation and Language · Computer Science 2025-10-31 Tarun Kumar Chawdhury , Jon D. Duke

Discharge summaries in Electronic Health Records (EHRs) are crucial for clinical decision-making, but their length and complexity make information extraction challenging, especially when dealing with accumulated summaries across multiple…

Computation and Language · Computer Science 2024-11-12 Sunjun Kweon , Jiyoun Kim , Heeyoung Kwak , Dongchul Cha , Hangyul Yoon , Kwanghyun Kim , Jeewon Yang , Seunghyun Won , Edward Choi

Identifying patient cohorts is fundamental to numerous healthcare tasks, including clinical trial recruitment and retrospective studies. Current cohort retrieval methods in healthcare organizations rely on automated queries of structured…

A promising application of AI to healthcare is the retrieval of information from electronic health records (EHRs), e.g. to aid clinicians in finding relevant information for a consultation or to recruit suitable patients for a study. This…

Computation and Language · Computer Science 2020-11-02 Claudia Schulz , Josh Levy-Kramer , Camille Van Assel , Miklos Kepes , Nils Hammerla

Electronic health record (EHR) systems present clinicians with vast repositories of clinical information, creating a significant cognitive burden where critical details are easily overlooked. While Large Language Models (LLMs) offer…

Computation and Language · Computer Science 2026-03-17 Samuel Thio , Matthew Lewis , Spiros Denaxas , Richard JB Dobson

Electronic Health Records (EHRs) contain rich yet complex information, and their automated analysis is critical for clinical decision-making. Despite recent advances of large language models (LLMs) in clinical workflows, their ability to…

Computation and Language · Computer Science 2025-11-26 Yusheng Liao , Chaoyi Wu , Junwei Liu , Shuyang Jiang , Pengcheng Qiu , Haowen Wang , Yun Yue , Shuai Zhen , Jian Wang , Qianrui Fan , Jinjie Gu , Ya Zhang , Yanfeng Wang , Yu Wang , Weidi Xie

Clinical prediction from structured electronic health records (EHRs) is challenging due to high dimensionality, heterogeneity, class imbalance, and distribution shift. While tabular in-context learning (TICL) and retrieval-augmented methods…

Current medical retrieval benchmarks primarily emphasize lexical or shallow semantic similarity, overlooking the reasoning-intensive demands that are central to clinical decision-making. In practice, physicians often retrieve authoritative…

Information Retrieval · Computer Science 2026-04-07 Xiangxu Zhang , Lei Li , Xiao Zhou , Zheng Liu

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

Objective: Applying large language models (LLMs) to the clinical domain is challenging due to the context-heavy nature of processing medical records. Retrieval-augmented generation (RAG) offers a solution by facilitating reasoning over…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Timothy A. Miller , Yanjun Gao , Matthew M. Churpek , Anoop Mayampurath , Dmitriy Dligach , Majid Afshar

The large amount of time clinicians spend sifting through patient notes and documenting in electronic health records (EHRs) is a leading cause of clinician burnout. By proactively and dynamically retrieving relevant notes during the…

Information Retrieval · Computer Science 2023-08-17 Sharon Jiang , Shannon Shen , Monica Agrawal , Barbara Lam , Nicholas Kurtzman , Steven Horng , David Karger , David Sontag

Real-world clinical text-to-SQL requires reasoning over heterogeneous EHR tables, temporal windows, and patient-similarity cohorts to produce executable queries. We introduce CLINSQL, a benchmark of 633 expert-annotated tasks on MIMIC-IV…

Computation and Language · Computer Science 2026-01-16 Yifei Shen , Yilun Zhao , Justice Ou , Tinglin Huang , Arman Cohan

The meaningful use of electronic health records (EHR) continues to progress in the digital era with clinical decision support systems augmented by artificial intelligence. A priority in improving provider experience is to overcome…

Computation and Language · Computer Science 2023-01-30 Yanjun Gao , Dmitriy Dligach , Timothy Miller , John Caskey , Brihat Sharma , Matthew M Churpek , Majid Afshar

Retrieving information from EHR systems is essential for answering specific questions about patient journeys and improving the delivery of clinical care. Despite this fact, most EHR systems still rely on keyword-based searches. With the…

Computation and Language · Computer Science 2024-04-11 Shashi Kant Gupta , Aditya Basu , Bradley Taylor , Anai Kothari , Hrituraj Singh

The ability of large language models (LLMs) to follow natural language instructions with human-level fluency suggests many opportunities in healthcare to reduce administrative burden and improve quality of care. However, evaluating LLMs on…

With their growing capabilities, generative large language models (LLMs) are being increasingly investigated for complex medical tasks. However, their effectiveness in real-world clinical applications remains underexplored. To address this,…

Computation and Language · Computer Science 2026-01-27 Paul Grundmann , Dennis Fast , Jan Frick , Thomas Steffek , Felix Gers , Wolfgang Nejdl , Alexander Löser

With the increasing use of RetrievalAugmented Generation (RAG), strong retrieval models have become more important than ever. In healthcare, multimodal retrieval models that combine information from both text and images offer major…

Information Retrieval · Computer Science 2025-10-09 Arkadeep Acharya , Akash Ghosh , Pradeepika Verma , Kitsuchart Pasupa , Sriparna Saha , Priti Singh

Electronic Health Records (EHRs) provide rich longitudinal clinical evidence that is central to medical decision-making, motivating the use of retrieval-augmented generation (RAG) to ground large language model (LLM) predictions. However,…

Artificial Intelligence · Computer Science 2026-01-30 Lang Cao , Qingyu Chen , Yue Guo

To improve the reliability of Large Language Models (LLMs) in clinical applications, retrieval-augmented generation (RAG) is extensively applied to provide factual medical knowledge. However, beyond general medical knowledge from open-ended…

Computation and Language · Computer Science 2025-05-29 Justice Ou , Tinglin Huang , Yilun Zhao , Ziyang Yu , Peiqing Lu , Rex Ying
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