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Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

Artificial intelligence (AI)-based chest X-ray (CXR) interpretation assistants have demonstrated significant progress and are increasingly being applied in clinical settings. However, contemporary medical AI models often adhere to a…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Jinquan Guan , Qi Chen , Lizhou Liang , Yuhang Liu , Vu Minh Hieu Phan , Minh-Son To , Jian Chen , Yutong Xie

Vision-language models (VLMs) have shown strong promise for medical image analysis, but most remain opaque, offering predictions without the transparent, stepwise reasoning clinicians rely on. We present a framework that brings…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Andriy Myronenko , Dong Yang , Baris Turkbey , Mariam Aboian , Sena Azamat , Esra Akcicek , Hongxu Yin , Pavlo Molchanov , Marc Edgar , Yufan He , Pengfei Guo , Yucheng Tang , Daguang Xu

Large vision-language models (VLMs) have evolved from general-purpose applications to specialized use cases such as in the clinical domain, demonstrating potential for decision support in radiology. One promising application is assisting…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Zhifan Jiang , Dong Yang , Vishwesh Nath , Abhijeet Parida , Nishad P. Kulkarni , Ziyue Xu , Daguang Xu , Syed Muhammad Anwar , Holger R. Roth , Marius George Linguraru

Medical report generation from imaging data remains a challenging task in clinical practice. While large language models (LLMs) show great promise in addressing this challenge, their effective integration with medical imaging data still…

Computer Vision and Pattern Recognition · Computer Science 2025-06-19 Chunlei Li , Jingyang Hou , Yilei Shi , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

Significant methodological strides have been made toward Chest X-ray (CXR) understanding via modern vision-language models (VLMs), demonstrating impressive Visual Question Answering (VQA) and CXR report generation abilities. However,…

Artificial Intelligence · Computer Science 2024-04-01 Seil Kang , Donghyun Kim , Junhyeok Kim , Hyo Kyung Lee , Seong Jae Hwang

Chest X-ray (CXR) plays a pivotal role in clinical diagnosis, and a variety of task-specific and foundation models have been developed for automatic CXR interpretation. However, these models often struggle to adapt to new diagnostic tasks…

Artificial Intelligence · Computer Science 2025-10-27 Jinhui Lou , Yan Yang , Zhou Yu , Zhenqi Fu , Weidong Han , Qingming Huang , Jun Yu

Multimodal Large Language Models (MLLMs) have shown strong potential for radiology report generation, yet their clinical translation is hindered by architectural heterogeneity and the prevalence of factual hallucinations. Standard…

Machine Learning · Computer Science 2026-01-13 Kun Zhao , Siyuan Dai , Pan Wang , Jifeng Song , Hui Ji , Chenghua Lin , Liang Zhan , Haoteng Tang

Radiology is essential to modern healthcare, yet rising demand and staffing shortages continue to pose major challenges. Recent advances in artificial intelligence have the potential to support radiologists and help address these…

Image and Video Processing · Electrical Eng. & Systems 2025-11-14 Phillip Sloan , Edwin Simpson , Majid Mirmehdi

The challenge of Multimodal Deformable Image Registration (MDIR) lies in the conversion and alignment of features between images of different modalities. Generative models (GMs) cannot retain the necessary information enough from the source…

Computer Vision and Pattern Recognition · Computer Science 2024-08-21 Mingrui Ma , Weijie Wang , Jie Ning , Jianfeng He , Nicu Sebe , Bruno Lepri

Chest X-ray (CXR) reporting follows a region-based clinical workflow in which radiologists inspect anatomical regions and integrate localized findings into a final report. However, existing resources for CXR report generation provide these…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Yichen Zhao , Zelin Peng , Fenghe Tang , Piao Yang , Yu Huang , Wei Shen

LLMs have demonstrated remarkable capabilities in linguistic reasoning and are increasingly adept at vision-language tasks. The integration of image tokens into transformers has enabled direct visual input and output, advancing research…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Jonghun Kim , Sinyoung Ra , Hyunjin Park

Despite significant progress, existing research on Multimodal Large Language Models (MLLMs) mainly focuses on general visual understanding, overlooking the ability to integrate textual context associated with objects for a more…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Hongliang Wei , Xianqi Zhang , Xingtao Wang , Xiaopeng Fan , Debin Zhao

Vision-language models (VLMs) have recently shown remarkable zero-shot performance in medical image understanding, yet their grounding ability, the extent to which textual concepts align with visual evidence, remains underexplored. In the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Haozhe Luo , Shelley Zixin Shu , Ziyu Zhou , Sebastian Otalora , Mauricio Reyes

Large language models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence technology which is rapidly evolving and promises to aid in medical diagnosis. However, the correctness and the accuracy of their returns has…

Computation and Language · Computer Science 2024-02-07 Dimitrios P. Panagoulias , Maria Virvou , George A. Tsihrintzis

Large Language Models (LLMs), known for their versatility in textual data, are increasingly being explored for their potential to enhance medical image segmentation, a crucial task for accurate diagnostic imaging. This study explores…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Gurucharan Marthi Krishna Kumar , Aman Chadha , Janine Mendola , Amir Shmuel

Recently, Multimodal Large Language Models (MLLMs) that enable Large Language Models (LLMs) to interpret images through visual instruction tuning have achieved significant success. However, existing visual instruction tuning methods only…

Computer Vision and Pattern Recognition · Computer Science 2023-09-15 Chi Chen , Ruoyu Qin , Fuwen Luo , Xiaoyue Mi , Peng Li , Maosong Sun , Yang Liu

There is growing interest in applying AI to radiology report generation, particularly for chest X-rays (CXRs). This paper investigates whether incorporating pixel-level information through segmentation masks can improve fine-grained image…

Recent advances in AI combine large language models (LLMs) with vision encoders that bring forward unprecedented technical capabilities to leverage for a wide range of healthcare applications. Focusing on the domain of radiology,…

CLIP and BiomedCLIP are examples of vision-language foundation models and offer strong cross-modal embeddings; however, they are not optimized for fine-grained medical retrieval tasks, such as retrieving clinically relevant radiology…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Zhaohui Liang , Sivaramakrishnan Rajaraman , Niccolo Marini , Zhiyun Xue , Sameer Antani