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We have investigated the role that different connectivity regimes play on the dynamics of a network of Hodgkin-Huxley neurons by computer simulations. The different connectivity topologies exhibit the following features: random connectivity…

Disordered Systems and Neural Networks · Physics 2025-03-24 Luis F. Lago-Fernandez , Ramon Huerta , Fernando Corbacho , Juan A. Siguenza

In this paper, we develop topological data analysis methods for classification tasks on univariate time series. As an application, we perform binary and ternary classification tasks on two public datasets that consist of physiological…

Machine Learning · Statistics 2021-06-15 Alperen Karan , Atabey Kaygun

We use topological data analysis to study neural population activity in the Sensorium 2023 dataset, which records responses from thousands of mouse visual cortex neurons to diverse video stimuli. For each video, we build frame-by-frame…

Algebraic Topology · Mathematics 2026-03-04 Yuri Gardinazzi , Alessio Ansuini , Eugenio Piasini , Fabio Anselmi , Matteo Biagetti

Brain network topology, derived from functional magnetic resonance imaging (fMRI), holds promise for improving Alzheimer's disease (AD) diagnosis. Current methods primarily focus on lower-order topological features, often overlooking the…

Geometric Topology · Mathematics 2025-09-19 Dengyi Zhao , Shanyong Li , Yunping Wang , Chenfei Wang , Zhiheng Zhou , Guiying Yan , Xingqin Qi

Topological Data Analysis (TDA) is the collection of mathematical tools that capture the structure of shapes in data. Despite computational topology and computational geometry, the utilization of TDA in time series and signal processing is…

Information Retrieval · Computer Science 2018-10-23 Shafie Gholizadeh , Wlodek Zadrozny

With the advances in high resolution neuroimaging, there has been a growing interest in the detection of functional brain connectivity. Complex network theory has been proposed as an attractive mathematical representation of functional…

Neural and Evolutionary Computing · Computer Science 2018-09-18 Arash Golibagh Mahyari , Selin Aviyente

Accurately characterizing higher-order interactions of brain regions and extracting interpretable organizational patterns from Functional Magnetic Resonance Imaging data is crucial for brain disease diagnosis. Current graph-based deep…

Neurons and Cognition · Quantitative Biology 2026-03-16 Dengyi Zhao , Zhiheng Zhou , Guiying Yan , Dongxiao Yu , Xingqin Qi

Brain regions are often topographically connected: nearby locations within one brain area connect with nearby locations in another area. Mapping these connection topographies, or 'connectopies' in short, is crucial for understanding how…

Quantitative Methods · Quantitative Biology 2017-07-18 Koen V. Haak , Andre F. Marquand , Christian F. Beckmann

Neural signals are characterized by rich temporal and spatiotemporal dynamics that reflect the organization of cortical networks. Theoretical research has shown how neural networks can operate at different dynamic ranges that correspond to…

Neurons and Cognition · Quantitative Biology 2017-07-05 Luca Ambrogioni , Marcel A. J. van Gerven , Eric Maris

The functional network of the brain continually adapts to changing environmental demands. The environmental changes closely connect with changes of active cognitive processes. In recent years, the network approach has emerged as a promising…

Neurons and Cognition · Quantitative Biology 2024-03-13 Ilya Ernston , Arsenii Onuchin , Timofey Adamovich

Understanding the structure of the brain, and how it changes with time and disease, is a core goal of structural neuroimaging. Contemporary approaches to structural brain analysis are dominated by voxel-wise, mass-univariate methods such as…

Algebraic Topology · Mathematics 2026-04-28 Donato Quiccione , Mariam Pirashvili , Nathan Broomhead , Sean J. Fallon

The assumption of using a static graph to represent multivariate time-varying signals oversimplifies the complexity of modeling their interactions over time. We propose a Dynamic Multi-hop model that captures dynamic interactions among…

Signal Processing · Electrical Eng. & Systems 2024-11-26 Yi Yan , Fengfan Zhao , Ercan Engin Kuruoglu

The problem of (point) forecasting $ \textit{univariate} $ time series is considered. Most approaches, ranging from traditional statistical methods to recent learning-based techniques with neural networks, directly operate on raw time…

Machine Learning · Computer Science 2021-07-21 Sebastian Zeng , Florian Graf , Christoph Hofer , Roland Kwitt

Modern imaging techniques for probing brain function, including functional Magnetic Resonance Imaging, intrinsic and extrinsic contrast optical imaging, and magnetoencephalography, generate large data sets with complex content. In this…

Neurons and Cognition · Quantitative Biology 2009-11-10 P. P. Mitra , B. Pesaran

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

Machine Learning · Computer Science 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

While time-frequency analysis provides rich representations of multicomponent signals, current decomposition methods often overlook the morphological structure where components manifest as distinct regions. This study introduces…

Signal Processing · Electrical Eng. & Systems 2025-11-26 Wei Zhou , Wei-Jian Li , Desen Zhu , Hongbin Xu , Wei-Xin Ren

We propose a topological framework for the detection of Hopf bifurcations directly from time series, based on persistent homology applied to phase space reconstructions via Takens embedding within the framework of Topological Data Analysis.…

Dynamical Systems · Mathematics 2026-03-31 Jhonathan Barrios , Yásser Echávez , Carlos F. Álvarez

One of the paramount challenges in neuroscience is to understand the dynamics of individual neurons and how they give rise to network dynamics when interconnected. Historically, researchers have resorted to graph theory, statistics, and…

Neurons and Cognition · Quantitative Biology 2019-02-08 Jean-Baptiste Bardin , Gard Spreemann , Kathryn Hess

Inferring topological and geometrical information from data can offer an alternative perspective on machine learning problems. Methods from topological data analysis, e.g., persistent homology, enable us to obtain such information,…

Computer Vision and Pattern Recognition · Computer Science 2018-02-19 Christoph Hofer , Roland Kwitt , Marc Niethammer , Andreas Uhl

Dynamic functional connectivity (DFC) analysis involves measuring correlated neural activity over time across multiple brain regions. Significant regional correlations among neural signals, such as those obtained from resting-state…