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Diffusion-based super-resolution (SR) models have recently garnered significant attention due to their potent restoration capabilities. But conventional diffusion models perform noise sampling from a single distribution, constraining their…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Chengcheng Wang , Zhiwei Hao , Yehui Tang , Jianyuan Guo , Yujie Yang , Kai Han , Yunhe Wang

Diffusion Probabilistic Models have demonstrated remarkable performance across a wide range of generative tasks. However, we have observed that these models often suffer from a Signal-to-Noise Ratio-timestep (SNR-t) bias. This bias refers…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Meng Yu , Lei Sun , Jianhao Zeng , Xiangxiang Chu , Kun Zhan

Diffusion-based image super-resolution methods have demonstrated significant advantages over GAN-based approaches, particularly in terms of perceptual quality. Building upon a lengthy Markov chain, diffusion-based methods possess remarkable…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Leheng Zhang , Weiyi You , Kexuan Shi , Shuhang Gu

Nuclear magnetic resonance (NMR) diffusion experiments are widely employed as they yield information about structures hindering the diffusion process, e.g. about cell membranes. While it has been shown in recent articles, that these…

Medical Physics · Physics 2013-05-08 Frederik Bernd Laun , Tristan Anselm Kuder

Modern technology for producing extremely bright and coherent X-ray laser pulses provides the possibility to acquire a large number of diffraction patterns from individual biological nanoparticles, including proteins, viruses, and DNA.…

Methodology · Statistics 2018-07-11 Stefan Engblom , Carl Nettelblad , Jing Liu

Spectroscopic techniques are essential tools for determining the structure of molecules. Different spectroscopic techniques, such as Nuclear magnetic resonance (NMR), Infrared spectroscopy, and Mass Spectrometry, provide insight into the…

Chemical Physics · Physics 2024-10-30 Marvin Alberts , Oliver Schilter , Federico Zipoli , Nina Hartrampf , Teodoro Laino

Nuclear Magnetic Resonance (NMR) is used in structural biology to experimentally determine the structure of proteins, which is used in many areas of biology and is an important part of drug development. Unfortunately, NMR data can cost…

Quantitative Methods · Quantitative Biology 2022-08-03 Jia Qi Yip , Dianwen Ng , Bin Ma , Konstantin Pervushin , Eng Siong Chng

Recent advances in powerful pre-trained diffusion models encourage the development of methods to improve the sampling performance under well-trained diffusion models. This paper introduces Diffusion Rejection Sampling (DiffRS), which uses a…

Machine Learning · Computer Science 2024-05-29 Byeonghu Na , Yeongmin Kim , Minsang Park , Donghyeok Shin , Wanmo Kang , Il-Chul Moon

Magnetic Resonance Fingerprinting (MRF) is a time-efficient approach to quantitative MRI, enabling the mapping of multiple tissue properties from a single, accelerated scan. However, achieving accurate reconstructions remains challenging,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-19 Perla Mayo , Carolin M. Pirkl , Alin Achim , Bjoern H. Menze , Mohammad Golbabaee

Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful and widely used tools for molecular structure elucidation in organic chemistry. However, the interpretation of NMR spectra to determine unknown molecular structures…

Chemical Physics · Physics 2025-09-03 Yongqi Jin , Jun-Jie Wang , Fanjie Xu , Xiaohong Ji , Zhifeng Gao , Linfeng Zhang , Guolin Ke , Rong Zhu , Weinan E

Porous carbonaceous materials have many important industrial applications including energy storage, water purification, and adsorption of volatile organic compounds. Most of their applications rely upon the adsorption of molecules or ions…

Materials Science · Physics 2020-12-15 Alexander C. Forse , Céline Merlet , Clare P. Grey , John M. Griffin

Diffusion Magnetic Resonance Imaging (dMRI) is an imaging technique with exquisite sensitivity to the microstructural properties of heterogeneous media. The conventionally adopted acquisition schemes involving single pulsed field gradients…

Biological Physics · Physics 2023-01-04 Deneb Boito , Cem Yolcu , Evren Özarslan

Nuclear Magnetic Resonance (NMR) spectroscopy is a widely-used technique in the fields of bio-medicine, chemistry, and biology for the analysis of chemicals and proteins. The signals from NMR spectroscopy often have low signal-to-noise…

Signal Processing · Electrical Eng. & Systems 2024-05-21 Zihao Zou , Shirin Shoushtari , Jiaming Liu , Jialiang Zhang , Patrick Judge , Emilia Santana , Alison Lim , Marcus Foston , Ulugbek S. Kamilov

Nuclear magnetic resonance (NMR) spectroscopy is a powerful method for the investigation of three-dimensional structures of biological molecules such as proteins. Determining a protein structure is essential for understanding its function…

Artificial Intelligence · Computer Science 2015-06-22 John Emmons , Steven Johnson , Timothy Urness , Adina Kilpatrick

Magnetic Resonance Imaging (MRI) is a powerful medical imaging modality, but unfortunately suffers from long scan times which, aside from increasing operational costs, can lead to image artifacts due to patient motion. Motion during the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-02 Brett Levac , Sidharth Kumar , Ajil Jalal , Jonathan I. Tamir

Multidimensional NMR spectroscopy is one of the basic tools for determining the structure of biomolecules. Unfortunately, the resolution of the spectra is often limited by inter-nuclear couplings. This limitation cannot be overcome by…

Brain cell structure and function reflect neurodevelopment, plasticity and ageing, and changes can help flag pathological processes such as neurodegeneration and neuroinflammation. Accurate and quantitative methods to non-invasively…

Diffusion generative models have emerged as a powerful framework for addressing problems in structural biology and structure-based drug design. These models operate directly on 3D molecular structures. Due to the unfavorable scaling of…

Biomolecules · Quantitative Biology 2024-05-10 Ian Dunn , David Ryan Koes

Deep learning methods for accelerated MRI achieve state-of-the-art results but largely ignore additional speedups possible with noncartesian sampling trajectories. To address this gap, we created a generative diffusion model-based…

Artificial Intelligence · Computer Science 2024-10-02 Trevor J. Chan , Chamith S. Rajapakse

Interferometry can measure the shape or the material density of a system that could not be measured otherwise by recording the difference between the phase change of a signal and a reference phase. This difference is always between $-\pi$…

Plasma Physics · Physics 2022-10-20 Pierre-Alexandre Gourdain , Aidan Bachmann