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Advancements in theoretical and algorithmic approaches, workflow engines, and an ever-increasing computational power have enabled a novel paradigm for materials discovery through first-principles high-throughput simulations. A major…

Machine learning methods have shown promise in predicting molecular properties, and given sufficient training data machine learning approaches can enable rapid high-throughput virtual screening of large libraries of compounds. Graph-based…

More and more massive parallel codes running on several hundreds of thousands of cores enter the computational science and engineering domain, allowing high-fidelity computations on up to trillions of unknowns for very detailed analyses of…

Performance · Computer Science 2018-07-18 Christoph Ertl , Jérôme Frisch , Ralf-Peter Mundani

Driven by the recent rapid increase in the number of materials databases published (open and commercial), I discuss here some perspectives on the growing need for standardized, interoperable, open databases. The field of computational…

Materials Science · Physics 2019-11-14 François-Xavier Coudert

High-throughput methods enable accelerated discovery of novel materials in complex systems such as high-entropy alloys, which exhibit intricate phase stability across vast compositional spaces. Computational approaches, including Density…

Understanding material failure is critical for designing stronger and lighter structures by identifying weaknesses that could be mitigated. Existing full-physics numerical simulation techniques involve trade-offs between speed, accuracy,…

Machine learning solutions are very popular in the field of chemoinformatics, where they have numerous applications, such as novel drug discovery or molecular property prediction. Molecular fingerprints are algorithms commonly used for…

Quantitative Methods · Quantitative Biology 2024-04-01 Michał Szafarczyk , Piotr Ludynia , Przemysław Kukla

Machine learning (ML)-accelerated discovery requires large amounts of high-fidelity data to reveal predictive structure-property relationships. For many properties of interest in materials discovery, the challenging nature and high cost of…

Chemical Physics · Physics 2021-11-04 Aditya Nandy , Chenru Duan , Heather J. Kulik

The ever-increasing need for fast data processing demands new methods for efficient query execution. Just-in-time query compilation techniques have been demonstrated to improve performance in a set of analytical tasks significantly. In this…

Databases · Computer Science 2018-08-17 Aleksei Kashuba , Hannes Mühleisen

We present an ensemble machine-learning approach for composition-based, structure-agnostic screening of candidate superconductors among ternary hydrides under high pressure. Hydrogen-rich hydrides are known to exhibit high superconducting…

Superconductivity · Physics 2026-05-18 Kazuaki Tokuyama , Souta Miyamoto , Taichi Masuda , Katsuaki Tanabe

We present an open-source database of superconducting quantum device designs that may be used as the starting point for customized devices. Each design can be generated programmatically using the open-source Qiskit Metal package, and…

In this paper, I discuss the challenges in porting hydrodynamic codes to futuristic exascale HPC systems. In particular, we describe the computational complexities of finite difference method, pseudo-spectral method, and Fast Fourier…

Computational Physics · Physics 2019-11-25 Mahendra K. Verma

The design of advanced nuclear reactors (Gen IV) involves an array of challenging fluid-flow issues that affect safety and performance. Currently, these problems are addressed in an ad-hoc manner at varying scales which are time-consuming…

Fluid Dynamics · Physics 2022-03-15 Tri Nguyen , Elia Merzari , Haomin Yuan

Material scientists are increasingly adopting the use of machine learning (ML) for making potentially important decisions, such as, discovery, development, optimization, synthesis and characterization of materials. However, despite ML's…

Computational Physics · Physics 2019-03-12 Bhavya Kailkhura , Brian Gallagher , Sookyung Kim , Anna Hiszpanski , T. Yong-Jin Han

Feature management is essential for many online machine learning applications and can often become the performance bottleneck (e.g., taking up to 70% of the overall latency in sales prediction service). Improper feature configurations…

Databases · Computer Science 2025-04-02 Xin Tong , Xuanhe Zhou , Bingsheng He , Guoliang Li , Zirui Tang , Wei Zhou , Fan Wu , Mian Lu , Yuqiang Chen

Building a sustainable burn platform in inertial confinement fusion (ICF) requires an understanding of the complex coupling of physical processes and the effects that key experimental design changes have on implosion performance. While…

All major weather and climate applications are currently developed using languages such as Fortran or C++. This is typical in the domain of high performance computing (HPC), where efficient execution is an important concern. Unfortunately,…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-11-15 Enrique G. Paredes , Linus Groner , Stefano Ubbiali , Hannes Vogt , Alberto Madonna , Kean Mariotti , Felipe Cruz , Lucas Benedicic , Mauro Bianco , Joost VandeVondele , Thomas C. Schulthess

Machine learning potentials (MLPs) for atomistic simulations have an enormous prospective impact on materials modeling, offering orders of magnitude speedup over density functional theory (DFT) calculations without appreciably sacrificing…

Materials Science · Physics 2022-01-20 Dylan Bayerl , Christopher M. Andolina , Shyam Dwaraknath , Wissam A. Saidi

The discovery of magnetic materials with high operating temperature ranges and optimized performance is essential for advanced applications. Current data-driven approaches are limited by the lack of accurate, comprehensive, and feature-rich…

Materials Science · Physics 2026-03-31 Suman Itani , Yibo Zhang , Jiadong Zang

Probabilistic graphical models (PGMs) serve as a powerful framework for modeling complex systems with uncertainty and extracting valuable insights from data. However, users face challenges when applying PGMs to their problems in terms of…

Machine Learning · Computer Science 2024-05-29 Jiantong Jiang , Zeyi Wen , Peiyu Yang , Atif Mansoor , Ajmal Mian