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Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

Neurons and Cognition · Quantitative Biology 2025-02-25 Bishal Thapaliya , Robyn Miller , Jiayu Chen , Yu-Ping Wang , Esra Akbas , Ram Sapkota , Bhaskar Ray , Pranav Suresh , Santosh Ghimire , Vince Calhoun , Jingyu Liu

We present a hierarchical, control theory inspired method for variational inference (VI) for neural stochastic differential equations (SDEs). While VI for neural SDEs is a promising avenue for uncertainty-aware reasoning in time-series, it…

Machine Learning · Computer Science 2025-05-26 Rembert Daems , Manfred Opper , Guillaume Crevecoeur , Tolga Birdal

Nonlinear optimal control problems are often solved with numerical methods that require knowledge of system's dynamics which may be difficult to infer, and that carry a large computational cost associated with iterative calculations. We…

Machine Learning · Computer Science 2019-03-08 Ekaterina Abramova , Luke Dickens , Daniel Kuhn , Aldo Faisal

Humans and animals have a rich and flexible understanding of the physical world, which enables them to infer the underlying dynamical trajectories of objects and events, plausible future states, and use that to plan and anticipate the…

Artificial Intelligence · Computer Science 2023-10-26 Aran Nayebi , Rishi Rajalingham , Mehrdad Jazayeri , Guangyu Robert Yang

Dynamic Causal Modeling (DCM) is a Bayesian framework for inferring on hidden (latent) neuronal states, based on measurements of brain activity. Since its introduction in 2003 for functional magnetic resonance imaging data, DCM has been…

Quantitative Methods · Quantitative Biology 2021-04-08 Inês Pereira , Stefan Frässle , Jakob Heinzle , Dario Schöbi , Cao Tri Do , Moritz Gruber , Klaas E. Stephan

Naturalistic fMRI characterizes the brain as a dynamic predictive engine driven by continuous sensory streams. However, modeling the causal forward evolution in realistic neural simulation is impeded by the timescale mismatch between…

Neurons and Cognition · Quantitative Biology 2026-02-05 Xuanhua Yin , Runkai Zhao , Lina Yao , Weidong Cai

The highly irregular spiking activity of cortical neurons and behavioral variability suggest that the brain could operate in a fundamentally probabilistic way. Mimicking how the brain implements and learns probabilistic computation could be…

Neural and Evolutionary Computing · Computer Science 2024-04-23 Yang Qi , Zhichao Zhu , Yiming Wei , Lu Cao , Zhigang Wang , Jie Zhang , Wenlian Lu , Jianfeng Feng

Controlling continuous-time dynamical systems is generally a two step process: first, identify or model the system dynamics with differential equations, then, minimize the control objectives to achieve optimal control function and optimal…

Artificial Intelligence · Computer Science 2024-04-23 Cheng Chi

We address the design and synthesis of optimal control strategies for high-dimensional stochastic dynamical systems. Such systems may be deterministic nonlinear systems evolving from random initial states, or systems driven by random…

Numerical Analysis · Mathematics 2020-08-26 Panos Lambrianides , Qi Gong , Daniele Venturi

Stochastic compositional optimization (SCO) has attracted considerable attention because of its broad applicability to important real-world problems. However, existing works on SCO assume that the projection within a solution update is…

Optimization and Control · Mathematics 2025-05-27 Shuoguang Yang , Wei You , Zhe Zhang , Ethan X. Fang

Purpose: Recently, there has been a revived interest in system neuroscience causation models, driven by their unique capability to unravel complex relationships in multi-scale brain networks. In this paper, we present a novel method that…

Systems and Control · Electrical Eng. & Systems 2025-10-03 Dachuan Song , Li Shen , Duy Duong-Tran , Xuan Wang

Understanding brain dynamics is important for neuroscience and mental health. Functional magnetic resonance imaging (fMRI) enables the measurement of neural activities through blood-oxygen-level-dependent (BOLD) signals, which represent…

Neurons and Cognition · Quantitative Biology 2025-06-16 Yifei Sun , Daniel Chahine , Qinghao Wen , Tianming Liu , Xiang Li , Yixuan Yuan , Fernando Calamante , Jinglei Lv

In this study, we develop a stochastic optimal control approach with reinforcement learning structure to learn the unknown parameters appeared in the drift and diffusion terms of the stochastic differential equation. By choosing an…

Optimization and Control · Mathematics 2023-08-22 Shuzhen Yang

We consider stochastic convex optimization problems where the objective is an expectation over smooth functions. For this setting we suggest a novel gradient estimate that combines two recent mechanism that are related to notion of…

Machine Learning · Computer Science 2025-03-06 Tehila Dahan , Kfir Y. Levy

Many relevant problems in the area of systems and control, such as controller synthesis, observer design and model reduction, can be viewed as optimization problems involving dynamical systems: for instance, maximizing performance in the…

Optimization and Control · Mathematics 2023-11-15 Pascal Den Boef , Jos Maubach , Wil Schilders , Nathan van de Wouw

Functional bilevel optimization (FBO) provides a powerful framework for hierarchical learning in function spaces, yet current methods are limited to static offline settings and perform suboptimally in online, non-stationary scenarios. We…

Machine Learning · Statistics 2026-01-23 Jason Bohne , Ieva Petrulionyte , Michael Arbel , Julien Mairal , Paweł Polak

Most existing neural network-based approaches for solving stochastic optimal control problems using the associated backward dynamic programming principle rely on the ability to simulate the underlying state variables. However, in some…

Machine Learning · Statistics 2024-01-30 Christian Yeo

The development of robust and generalisable models for encoding the spatio-temporal dynamics of human brain activity is crucial for advancing neuroscientific discoveries. However, significant individual variation in the organisation of the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Simon Dahan , Logan Z. J. Williams , Yourong Guo , Daniel Rueckert , Emma C. Robinson

Recent advancements in diffusion models and diffusion bridges primarily focus on finite-dimensional spaces, yet many real-world problems necessitate operations in infinite-dimensional function spaces for more natural and interpretable…

Machine Learning · Computer Science 2025-03-03 Byoungwoo Park , Jungwon Choi , Sungbin Lim , Juho Lee

Faithfully simulating the dynamics of open quantum systems requires efficiently addressing the challenge of an infinite Hilbert space. Inspired by the shifted boson operator technique used in ground-state studies of the spin-boson model…

Quantum Physics · Physics 2025-08-27 Yang Zhao , Lipeng Chen