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We introduce a scheme for deriving an optimally-parametrised Langevin dynamics of few collective variables from data generated in molecular dynamics simulations. The drift and the position-dependent diffusion profiles governing the Langevin…

Statistical Mechanics · Physics 2008-08-22 Cristian Micheletti , Giovanni Bussi , Alessandro Laio

We derive and analyze numerical methods for underdamped (kinetic) Langevin dynamics in a domain with elastic reflection at the boundary. First-order approximations are based on an Euler-type scheme incorporating collision-handling at the…

Numerical Analysis · Mathematics 2025-12-10 B. Leimkuhler , A. Sharma , M. V. Tretyakov

Langevin integrators based on operator splitting are widely used in molecular dynamics. This work examines Langevin splitting schemes from the perspective of their internal trajectories and observation points, complementing existing…

Statistical Mechanics · Physics 2026-02-03 Bettina G. Keller

We present a comparative study of Langevin dynamics and a Metropolis random walk model applied to thermal neutron-induced fission of $^{229}$Th, $^{235}$U, $^{239}$Pu, $^{245}$Cm, $^{249}$Cf, and $^{255}$Fm. Both methods are implemented…

Nuclear Theory · Physics 2026-05-04 A. Augustyn , T. Cap , M. Kowal , K. Pomorski

The quantitative convergence to equilibrium for reaction-diffusion systems arising from complex balanced chemical reaction networks with mass action kinetics is studied by using the so-called entropy method. In the first part of the paper,…

Analysis of PDEs · Mathematics 2016-11-11 Laurent Desvillettes , Klemens Fellner , Bao Quoc Tang

A theory for chemical reaction dynamics in condensed phase systems based on the generalized Langevin formalism of Grote and Hynes is presented. A microscopic approach to calculate the dynamic friction is developed within the framework of a…

Statistical Mechanics · Physics 2009-11-10 Nurit Shental , Eran Rabani

Microscopic formula to describe the entropy of biomolecular solutions are derived based on the Gibbs formula of entropy, and the generalized Langevin theory combined with the RISM/3D-RISM theory. Two formula are derived: one is concerned…

Statistical Mechanics · Physics 2023-03-02 Fumio Hirata

Following [21, 23], the present work investigates a new relative entropy-regularized algorithm for solving the optimal transport on a graph problem within the randomized shortest paths formalism. More precisely, a unit flow is injected into…

Machine Learning · Computer Science 2021-09-21 Sylvain Courtain , Guillaume Guex , Ilkka Kivimaki , Marco Saerens

Reaction-diffusion equations are widely used as the governing evolution equations for modeling many physical, chemical, and biological processes. Here we derive reaction-diffusion equations to model transport with reactions on a…

Statistical Mechanics · Physics 2020-09-16 E. Abad , C. N. Angstmann , B. I. Henry , A. V. McGann , F. Le Vot , S. B. Yuste

Simplicity is a critical inductive bias for designing data-driven controllers, especially when robustness is important. Despite the impressive results of deep reinforcement learning in complex control tasks, it is prone to capturing…

Machine Learning · Computer Science 2025-05-09 Bang You , Chenxu Wang , Huaping Liu

A central object in the computational studies of rare events is the committor function. Though costly to compute, the committor function encodes complete mechanistic information of the processes involving rare events, including reaction…

Statistical Mechanics · Physics 2022-11-23 Muhammad R. Hasyim , Clay H. Batton , Kranthi K. Mandadapu

We study the trajectories of a solution $X_t$ to an It\^o stochastic differential equation in $\Rm^d$, as the process passes between two disjoint open sets, $A$ and $B$. These segments of the trajectory are called transition paths or…

Probability · Mathematics 2013-03-08 Jianfeng Lu , James Nolen

We consider the problem of approximating the Langevin dynamics of inertial particles being transported by a background flow. In particular, we study an acceleration corrected advection-diffusion approximation to the Langevin dynamics, a…

Probability · Mathematics 2026-02-24 Yoichiro Mori , Chanoknun Sintavanuruk , Truong-Son P. Van

We investigate random walks on a lattice with imperfect traps. In one dimension, we perturbatively compute the survival probability by reducing the problem to a particle diffusing on a closed ring containing just one single trap. Numerical…

Statistical Mechanics · Physics 2015-06-24 Timo Aspelmeier , Jérôme Magnin , Willi Graupner , Uwe C. Täuber

We propose a trajectory-based quasiclassical method for approximating dynamics in condensed phase systems. Building upon the previously developed Optimized Mean Trajectory (OMT) approximation that has been used to compute linear and…

Chemical Physics · Physics 2024-08-23 Kritanjan Polley

We propose a method to exactly generate bridge run-and-tumble trajectories that are constrained to start at the origin with a given velocity and to return to the origin after a fixed time with another given velocity. The method extends the…

Statistical Mechanics · Physics 2021-09-22 Benjamin De Bruyne , Satya N. Majumdar , Gregory Schehr

Relativistic effects in the thermodynamical properties of interacting particle systems are investigated within the framework of the relativistic direct interaction theory in various forms of dynamics. In the front form of relativistic…

High Energy Physics - Theory · Physics 2007-05-23 V. Tretyak

Trajectories represent the mobility of moving objects and thus is of great value in data mining applications. However, trajectory data is enormous in volume, so it is expensive to store and process the raw data directly. Trajectories are…

Databases · Computer Science 2020-10-20 Yunheng Han , Hanan Samet

Condensed ionic systems are described in the framework of a combined approach that takes into account both long-range and short-range interactions. Short-range interaction is expressed in terms of mean potentials and long-range interaction…

Statistical Mechanics · Physics 2019-10-03 G. Bokun , I. Kravtsiv , M. Holovko , V. Vikhrenko , D. di Caprio

Transfer entropy has been used to quantify the directed flow of information between source and target variables in many complex systems. While transfer entropy was originally formulated in discrete time, in this paper we provide a framework…

Information Theory · Computer Science 2017-04-05 Richard E. Spinney , Mikhail Prokopenko , Joseph T. Lizier