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Purpose: Accurate dose calculation is essential in radiotherapy for precise tumor irradiation while sparing healthy tissue. With the growing adoption of MRI-guided and real-time adaptive radiotherapy, fast and accurate dose calculation on…

Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…

Medical Physics · Physics 2020-07-01 Yixun Xing , Dan Nguyen , Weiguo Lu , Ming Yang , Steve Jiang

The large number of trainable parameters of deep neural networks renders them inherently data hungry. This characteristic heavily challenges the medical imaging community and to make things even worse, many imaging modalities are ambiguous…

Neural and Evolutionary Computing · Computer Science 2017-11-29 Simon Kohl , David Bonekamp , Heinz-Peter Schlemmer , Kaneschka Yaqubi , Markus Hohenfellner , Boris Hadaschik , Jan-Philipp Radtke , Klaus Maier-Hein

Background: Transrectal ultrasound guided systematic biopsies of the prostate is a routine procedure to establish a prostate cancer diagnosis. However, the 10-12 prostate core biopsies only sample a relatively small volume of the prostate,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-20 Bojing Liu , Yinxi Wang , Philippe Weitz , Johan Lindberg , Johan Hartman , Lars Egevad , Henrik Grönberg , Martin Eklund , Mattias Rantalainen

Background and purpose: Radiation-induced erectile dysfunction (RiED) is commonly seen in prostate cancer patients. Clinical trials have been developed in multiple institutions to investigate whether dose-sparing to the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-06 Anjali Balagopal , Michael Dohopolski , Young Suk Kwon , Steven Montalvo , Howard Morgan , Ti Bai , Dan Nguyen , Xiao Liang , Xinran Zhong , Mu-Han Lin , Neil Desai , Steve Jiang

Prostate cancer is a major cause of cancer-related deaths in men, where early detection greatly improves survival rates. Although MRI-TRUS fusion biopsy offers superior accuracy by combining MRI's detailed visualization with TRUS's…

Prostate cancer (PCa) is the most common cancer in men in the United States. Multiparametic magnetic resonance imaging (mp-MRI) has been explored by many researchers to targeted prostate biopsies and radiation therapy. However, assessment…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Zhenzhen Dai , Eric Carver , Chang Liu , Joon Lee , Aharon Feldman , Weiwei Zong , Milan Pantelic , Mohamed Elshaikh , Ning Wen

A novel deep learning architecture (XmasNet) based on convolutional neural networks was developed for the classification of prostate cancer lesions, using the 3D multiparametric MRI data provided by the PROSTATEx challenge. End-to-end…

Computer Vision and Pattern Recognition · Computer Science 2017-03-14 Saifeng Liu , Huaixiu Zheng , Yesu Feng , Wei Li

The 2024 Brain Tumor Segmentation Meningioma Radiotherapy (BraTS-MEN-RT) challenge aimed to advance automated segmentation algorithms using the largest known multi-institutional dataset of 750 radiotherapy planning brain MRIs with…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Dominic LaBella , Valeriia Abramova , Mehdi Astaraki , Andre Ferreira , Zhifan Jiang , Mason C. Cleveland , Ramandeep Kang , Uma M. Lal-Trehan Estrada , Cansu Yalcin , Rachika E. Hamadache , Clara Lisazo , Adrià Casamitjana , Joaquim Salvi , Arnau Oliver , Xavier Lladó , Iuliana Toma-Dasu , Tiago Jesus , Behrus Puladi , Jens Kleesiek , Victor Alves , Jan Egger , Daniel Capellán-Martín , Abhijeet Parida , Austin Tapp , Xinyang Liu , Maria J. Ledesma-Carbayo , Jay B. Patel , Thomas N. McNeal , Maya Viera , Owen McCall , Albert E. Kim , Elizabeth R. Gerstner , Christopher P. Bridge , Katherine Schumacher , Michael Mix , Kevin Leu , Shan McBurney-Lin , Pierre Nedelec , Javier Villanueva-Meyer , David R. Raleigh , Jonathan Shapey , Tom Vercauteren , Kazumi Chia , Marina Ivory , Theodore Barfoot , Omar Al-Salihi , Justin Leu , Lia M. Halasz , Yuri S. Velichko , Chunhao Wang , John P. Kirkpatrick , Scott R. Floyd , Zachary J. Reitman , Trey C. Mullikin , Eugene J. Vaios , Christina Huang , Ulas Bagci , Sean Sachdev , Jona A. Hattangadi-Gluth , Tyler M. Seibert , Nikdokht Farid , Connor Puett , Matthew W. Pease , Kevin Shiue , Syed Muhammad Anwar , Shahriar Faghani , Peter Taylor , Pranav Warman , Jake Albrecht , András Jakab , Mana Moassefi , Verena Chung , Rong Chai , Alejandro Aristizabal , Alexandros Karargyris , Hasan Kassem , Sarthak Pati , Micah Sheller , Nazanin Maleki , Rachit Saluja , Florian Kofler , Christopher G. Schwarz , Philipp Lohmann , Phillipp Vollmuth , Louis Gagnon , Maruf Adewole , Hongwei Bran Li , Anahita Fathi Kazerooni , Nourel Hoda Tahon , Udunna Anazodo , Ahmed W. Moawad , Bjoern Menze , Marius George Linguraru , Mariam Aboian , Benedikt Wiestler , Ujjwal Baid , Gian-Marco Conte , Andreas M. Rauschecker , Ayman Nada , Aly H. Abayazeed , Raymond Huang , Maria Correia de Verdier , Jeffrey D. Rudie , Spyridon Bakas , Evan Calabrese

The fastMRI brain and knee dataset has enabled significant advances in exploring reconstruction methods for improving speed and image quality for Magnetic Resonance Imaging (MRI) via novel, clinically relevant reconstruction approaches. In…

Deep learning-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment…

Medical Physics · Physics 2024-12-02 Sangwook Kim , Aly Khalifa , Thomas G. Purdie , Chris McIntosh

Many diagnostic and therapeutic clinical tasks for prostate cancer increasingly rely on multi-parametric MRI. Automating these tasks is challenging because they necessitate expert interpretations, which are difficult to scale to capitalise…

Brain metastases are a common diagnosis that affects between 20% and 40% of cancer patients. Subsequent to radiation therapy, patients with brain metastases undergo follow-up sessions during which the response to treatment is monitored. In…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Margarida Fernandes , José Soares , Matheus Silva , Crystian Saraiva , Victor Alves

With the wealth of medical image data, efficient curation is essential. Assigning the sequence type to magnetic resonance images is necessary for scientific studies and artificial intelligence-based analysis. However, incomplete or missing…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 Deepa Krishnaswamy , Bálint Kovács , Stefan Denner , Steve Pieper , David Clunie , Christopher P. Bridge , Tina Kapur , Klaus H. Maier-Hein , Andrey Fedorov

Prostate Cancer (PCa) is a prevalent disease among men, and multi-parametric MRIs offer a non-invasive method for its detection. While MRI-based deep learning solutions have shown promise in supporting PCa diagnosis, acquiring sufficient…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Meng Zhou , Amoon Jamzad , Jason Izard , Alexandre Menard , Robert Siemens , Parvin Mousavi

Resection and whole brain radiotherapy (WBRT) are the standards of care for the treatment of patients with brain metastases (BM) but are often associated with cognitive side effects. Stereotactic radiosurgery (SRS) involves a more targeted…

Recently, a new form of magnetic resonance imaging (MRI) called synthetic correlated diffusion (CDI$^s$) imaging was introduced and showed considerable promise for clinical decision support for cancers such as prostate cancer when compared…

Image and Video Processing · Electrical Eng. & Systems 2023-04-13 Chi-en Amy Tai , Hayden Gunraj , Alexander Wong

Brain metastases are a common complication of systemic cancer, affecting over 20% of patients with primary malignancies. Longitudinal magnetic resonance imaging (MRI) is essential for diagnosing patients, tracking disease progression,…

Prostate cancer is the most abundant cancer in men, with over 200,000 expected new cases and around 28,000 deaths in 2012 in the US alone. In this study, the segmentation results for the prostate central gland (PCG) in MR scans are…

Computer Vision and Pattern Recognition · Computer Science 2013-10-15 Jan Egger

Clinically significant prostate cancer has a better chance to be sampled during ultrasound-guided biopsy procedures, if suspected lesions found in pre-operative magnetic resonance (MR) images are used as targets. However, the diagnostic…

Machine Learning · Computer Science 2022-07-25 Iani JMB Gayo , Shaheer U. Saeed , Dean C. Barratt , Matthew J. Clarkson , Yipeng Hu