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Given a question, a language model (LM) implicitly encodes a distribution over possible answers. In practice, post-training procedures for LMs often collapse this distribution onto a single dominant mode. While this is generally not a…

Machine Learning · Computer Science 2026-03-27 Isha Puri , Mehul Damani , Idan Shenfeld , Marzyeh Ghassemi , Jacob Andreas , Yoon Kim

Model-based reinforcement learning (MBRL) provides a way to learn a transition model of the environment, which can then be used to plan personalized policies for different patient cohorts and to understand the dynamics involved in the…

Machine Learning · Computer Science 2024-11-22 Abhishek Sharma , Sonali Parbhoo , Omer Gottesman , Finale Doshi-Velez

Radiative processes such as synchrotron radiation and Compton scattering play an important role in astrophysics. Radiative processes are fundamentally stochastic in nature, and the best tools currently used for resolving these processes…

High Energy Astrophysical Phenomena · Physics 2024-06-28 William Charles , Alexander Y. Chen

Computed tomography (CT) and clinical numeric data are essential modalities for cancer evaluation, but building large-scale multimodal training datasets for developing medical foundation models remains challenging due to the structural…

Computer Vision and Pattern Recognition · Computer Science 2025-01-24 Daeun Jung , Jaehyeok Jang , Sooyoung Jang , Yu Rang Park

While the use of combination therapy is increasing in prevalence for cancer treatment, it is often difficult to predict the exact interactions between different treatment forms, and their synergistic/antagonistic effects on patient health…

Optimization and Control · Mathematics 2021-01-29 Jayanth Pratap

The increasing scale of manycore systems poses significant challenges in managing reliability while meeting performance demands. Simultaneously, these systems become more susceptible to different aging mechanisms such as negative-bias…

Machine Learning · Computer Science 2024-12-30 Fatemeh Hossein-Khani , Omid Akbari

Medical Ultrasound (US) imaging has seen increasing demands over the past years, becoming one of the most preferred imaging modalities in clinical practice due to its affordability, portability, and real-time capabilities. However, it faces…

LLM-based Multi-Agent Systems have demonstrated remarkable capabilities in addressing complex, agentic tasks, from generating high-quality presentation slides to even conducting sophisticated scientific research. Meanwhile, RL has been…

Multiagent Systems · Computer Science 2025-11-04 Junwei Liao , Muning Wen , Jun Wang , Weinan Zhang

Immunotherapy constitutes a paradigm shift in cancer treatment. Its FDA approval for several indications has yielded improved prognosis for cases where traditional therapy has shown limited efficiencey. However, many patients still fail to…

Medical Physics · Physics 2023-08-08 Nikita Vladimirov , Or Perlman

We introduce MARL-MambaContour, the first contour-based medical image segmentation framework based on Multi-Agent Reinforcement Learning (MARL). Our approach reframes segmentation as a multi-agent cooperation task focused on generate…

Computer Vision and Pattern Recognition · Computer Science 2025-07-16 Ruicheng Zhang , Yu Sun , Zeyu Zhang , Jinai Li , Xiaofan Liu , Au Hoi Fan , Haowei Guo , Puxin Yan

Task and motion planning (TAMP) for robotics manipulation necessitates long-horizon reasoning involving versatile actions and skills. While deterministic actions can be crafted by sampling or optimizing with certain constraints, planning…

Robotics · Computer Science 2025-10-17 Gaoyuan Liu , Joris de Winter , Yuri Durodie , Denis Steckelmacher , Ann Nowe , Bram Vanderborght

Medical Large Vision-Language Models (Med-LVLMs) have shown strong potential in multimodal diagnostic tasks. However, existing single-agent models struggle to generalize across diverse medical specialties, limiting their performance. Recent…

Machine Learning · Computer Science 2026-01-27 Peng Xia , Jinglu Wang , Yibo Peng , Kaide Zeng , Zihan Dong , Xian Wu , Xiangru Tang , Hongtu Zhu , Yun Li , Linjun Zhang , Shujie Liu , Yan Lu , Huaxiu Yao

Recently, reinforcement learning (RL)-based tuning has shifted the trajectory of Multimodal Large Language Models (MLLMs), particularly following the introduction of Group Relative Policy Optimization (GRPO). However, directly applying it…

Computation and Language · Computer Science 2025-05-21 Wenhui Zhu , Xuanzhao Dong , Xin Li , Peijie Qiu , Xiwen Chen , Abolfazl Razi , Aris Sotiras , Yi Su , Yalin Wang

MTL is a learning paradigm that effectively leverages both task-specific and shared information to address multiple related tasks simultaneously. In contrast to STL, MTL offers a suite of benefits that enhance both the training process and…

Modern external beam cancer radiotherapy applies prescribed radiation doses to tumor targets while minimally affecting nearby vulnerable organs-at-risk (OARs). Creating a treatment plan is difficult and time-consuming with no guarantee of…

Medical Physics · Physics 2021-07-07 Lyndon Hibbard

Reinforcement Learning (RL) is a potent tool for sequential decision-making and has achieved performance surpassing human capabilities across many challenging real-world tasks. As the extension of RL in the multi-agent system domain,…

Artificial Intelligence · Computer Science 2024-08-20 Ruiqi Zhang , Jing Hou , Florian Walter , Shangding Gu , Jiayi Guan , Florian Röhrbein , Yali Du , Panpan Cai , Guang Chen , Alois Knoll

Radiotherapy (RT) is a key component in the treatment of various cancers, including Acute Lymphocytic Leukemia (ALL) and Acute Myelogenous Leukemia (AML). Precise delineation of organs at risk (OARs) and target areas is essential for…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Ricardo Coimbra Brioso , Damiano Dei , Ciro Franzese , Nicola Lambri , Daniele Loiacono , Pietro Mancosu , Marta Scorsetti

Multimodal Large Language Models (MLLMs) perform well in single-image visual grounding but struggle with real-world tasks that demand cross-image reasoning and multi-modal instructions. To address this, we adopt a reinforcement learning…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Bob Zhang , Haoran Li , Tao Zhang , Jianan Li , Cilin Yan , Xikai Liu , Jiayin Cai , Yanbin Hao

Medical imaging has revolutionized diagnosis, yet unnecessary procedures are rising, exposing patients to radiation and stress, limiting equitable access, and straining healthcare systems. The American College of Radiology Appropriateness…

Quantitative Methods · Quantitative Biology 2025-10-08 Anni Tziakouri , Filippo Menolascina

Over the past decade, the use of machine learning (ML) models in healthcare applications has rapidly increased. Despite high performance, modern ML models do not always capture patterns the end user requires. For example, a model may…