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This article reviews the evolving field of radiobiology, emphasizing the need for advanced multiscale, mechanistic models to optimize radiopharmaceutical therapies (RPT). While the traditional linear-quadratic (LQ) model underpins external…

Medical Physics · Physics 2025-09-23 Tahir Yusufaly , Hamid Abdollahi , Babak Saboury , Arman Rahmim

Reinforcement learning (RL) is gaining attention by more and more researchers in quantitative finance as the agent-environment interaction framework is aligned with decision making process in many business problems. Most of the current…

Mathematical Finance · Quantitative Finance 2022-05-31 Huifang Huang , Ting Gao , Yi Gui , Jin Guo , Peng Zhang

The manufacturing sector was recently affected by workforce shortages, a problem that automation and robotics can heavily minimize. Simultaneously, reinforcement learning (RL) offers a promising solution where robots can learn through…

Robotics · Computer Science 2024-10-29 Abdalwhab Abdalwhab , Giovanni Beltrame , David St-Onge

Imaging demonstrates that preclinical and human tumors are heterogeneous, i.e. a single tumor can exhibit multiple regions that behave differently during both normal development and also in response to treatment. The large variations…

Computer Vision and Pattern Recognition · Computer Science 2022-09-08 P. D. Tar , N. A. Thacker , J. P. B. O'Connor

Effective interactive tool use requires agents to master Tool Integrated Reasoning (TIR): a complex process involving multi-turn planning and long-context dialogue management. To train agents for this dynamic process, particularly in…

Computation and Language · Computer Science 2025-09-19 Weiting Tan , Xinghua Qu , Ming Tu , Meng Ge , Andy T. Liu , Philipp Koehn , Lu Lu

Large Language Models (LLMs) have demonstrated remarkable capabilities in knowledge acquisition, reasoning, and tool use, making them promising candidates for autonomous agent applications. However, training LLM agents for complex…

Machine Learning · Computer Science 2025-12-09 Hanjiang Hu , Changliu Liu , Na Li , Yebin Wang

Recent advances in general medical AI have made significant strides, but existing models often lack the reasoning capabilities needed for complex medical decision-making. This paper presents GMAI-VL-R1, a multimodal medical reasoning model…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Yanzhou Su , Tianbin Li , Jiyao Liu , Chenglong Ma , Junzhi Ning , Cheng Tang , Sibo Ju , Jin Ye , Pengcheng Chen , Ming Hu , Shixiang Tang , Lihao Liu , Bin Fu , Wenqi Shao , Xiaowei Hu , Xiangwen Liao , Yuanfeng Ji , Junjun He

Head-and-neck cancer (HNC) planning is difficult because multiple critical organs-at-risk (OARs) are close to complex targets. Intensity-modulated carbon-ion therapy (IMCT) offers superior dose conformity and OAR sparing but remains slow…

Machine Learning · Computer Science 2025-11-05 Jueye Zhang , Chao Yang , Youfang Lai , Kai-Wen Li , Wenting Yan , Yunzhou Xia , Haimei Zhang , Jingjing Zhou , Gen Yang , Chen Lin , Tian Li , Yibao Zhang

Reinforcement learning (RL) is a flexible and efficient method for programming micro-robots in complex environments. Here we investigate whether reinforcement learning can provide insights into biological systems when trained to perform…

Biological Physics · Physics 2024-04-03 Samuel Tovey , Christoph Lohrmann , Christian Holm

Autonomous manipulation of granular media, such as sand, is crucial for applications in construction, excavation, and additive manufacturing. However, shaping granular materials presents unique challenges due to their high-dimensional…

Robotics · Computer Science 2025-09-10 Benedikt Kreis , Malte Mosbach , Anny Ripke , Muhammad Ehsan Ullah , Sven Behnke , Maren Bennewitz

Manipulation tasks such as preparing a meal or assembling furniture remain highly challenging for robotics and vision. Traditional task and motion planning (TAMP) methods can solve complex tasks but require full state observability and are…

Machine Learning · Computer Science 2020-06-23 Robin Strudel , Alexander Pashevich , Igor Kalevatykh , Ivan Laptev , Josef Sivic , Cordelia Schmid

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Reinforcement learning (RL) is a promising approach for robotic manipulation, but it can suffer from low sample efficiency and requires extensive exploration of large state-action spaces. Recent methods leverage the commonsense knowledge…

Robotics · Computer Science 2026-04-15 Jelle Luijkx , Runyu Ma , Zlatan Ajanović , Jens Kober

Multi-Objective Reinforcement Learning (MORL) is a generalization of traditional Reinforcement Learning (RL) that aims to optimize multiple, often conflicting objectives simultaneously rather than focusing on a single reward. This approach…

Machine Learning · Computer Science 2025-08-15 Davide Guidobene , Lorenzo Benedetti , Diego Arapovic

Precise robot manipulation is critical for fine-grained applications such as chemical and biological experiments, where even small errors (e.g., reagent spillage) can invalidate an entire task. Existing approaches often rely on…

Robotics · Computer Science 2026-02-13 Xiangyu Chen , Chuhao Zhou , Yuxi Liu , Jianfei Yang

Medical imaging is playing a more and more important role in clinics. However, there are several issues in different imaging modalities such as slow imaging speed in MRI, radiation injury in CT and PET. Therefore, accelerating MRI, reducing…

Computer Vision and Pattern Recognition · Computer Science 2019-09-06 Jing Cheng , Haifeng Wang , Yanjie Zhu , Qiegen Liu , Qiyang Zhang , Ting Su , Jianwei Chen , Yongshuai Ge , Zhanli Hu , Xin Liu , Hairong Zheng , Leslie Ying , Dong Liang

We propose a Reinforcement Learning (RL) based control design framework for handling complex tasks. The approach extends the concept of Reward Machines (RM) with Signal Temporal Logic (STL) formulas that can be used for event generation.…

Artificial Intelligence · Computer Science 2026-04-17 Ana María Gómez Ruiz , Thao Dang , Alexandre Donzé

Dynamic portfolio optimization is the process of sequentially allocating wealth to a collection of assets in some consecutive trading periods, based on investors' return-risk profile. Automating this process with machine learning remains a…

Machine Learning · Computer Science 2019-01-28 Pengqian Yu , Joon Sern Lee , Ilya Kulyatin , Zekun Shi , Sakyasingha Dasgupta

Large language models (LLMs) struggle in real-world clinical consultations. Single-turn consultation systems require patients to describe all symptoms at once, which often leads to unclear complaints and vague diagnoses. Traditional…

Computation and Language · Computer Science 2026-05-01 Yichun Feng , Jiawei Wang , Lu Zhou , Yikai Zheng , Zhen Lei , Yixue Li

Fine-tuning large language models (LLMs) is computationally expensive, and Low-Rank Adaptation (LoRA) provides a cost-effective solution by approximating weight updates through low-rank matrices. In real-world scenarios, LLMs are fine-tuned…

Machine Learning · Computer Science 2025-06-03 Jinda Liu , Yi Chang , Yuan Wu