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Winfree's abstract Tile Assembly Model (aTAM) is a model of molecular self-assembly of DNA complexes known as tiles, which float freely in solution and attach one at a time to a growing "seed" assembly based on specific binding sites on…

Computational Complexity · Computer Science 2015-03-17 Ho-Lin Chen , David Doty , Shinnosuke Seki

We consider principal pivot transform (pivot) on graphs. We define a natural variant of this operation, called dual pivot, and show that both the kernel and the set of maximally applicable pivots of a graph are invariant under this…

Combinatorics · Mathematics 2010-10-15 Robert Brijder , Hendrik Jan Hoogeboom

In this paper we present a novel framework for sequence to shape maps. These combinatorial maps realize exponentially many shapes, and have preimages which contain extended connected subgraphs of diameter n (neutral networks). We prove that…

Quantitative Methods · Quantitative Biology 2009-09-29 Emma Y. Jin , Jing Qin , Christian M. Reidys

Generating realistic graph-structured data is challenging due to discrete connectivity, varying graph sizes, and class-specific structural patterns. Recent Generative Adversarial Networks (GAN)-based graph generation methods improve edge…

Machine Learning · Computer Science 2026-05-29 James Sargant , Seyedeh Ava Razi Razavi , Renata Dividino , Sheridan Houghten

Designing molecules with specific properties is a long-lasting research problem and is central to advancing crucial domains such as drug discovery and material science. Recent advances in deep graph generative models treat molecule design…

Machine Learning · Computer Science 2022-03-02 Yuanqi Du , Xiaojie Guo , Amarda Shehu , Liang Zhao

Given graphs $F$ and $G$, a perfect $F$-tiling in $G$ is a collection of vertex-disjoint copies of $F$ in $G$ that together cover all the vertices in $G$. The study of the minimum degree threshold forcing a perfect $F$-tiling in a graph $G$…

Combinatorics · Mathematics 2023-10-18 Igor Araujo , Simón Piga , Andrew Treglown , Zimu Xiang

Graph Neural Networks (GNNs), which generalize the deep neural networks to graph-structured data, have achieved great success in modeling graphs. However, as an extension of deep learning for graphs, GNNs lack explainability, which largely…

Machine Learning · Computer Science 2021-08-30 Enyan Dai , Suhang Wang

Graph generation techniques are increasingly being adopted for drug discovery. Previous graph generation approaches have utilized relatively small molecular building blocks such as atoms or simple cycles, limiting their effectiveness to…

Machine Learning · Computer Science 2020-04-21 Wengong Jin , Regina Barzilay , Tommi Jaakkola

A graph is said to be NSSD (= non-singular with a singular deck) if it has no eigenvalue equal to zero, whereas all its vertex-deleted subgraphs have eigenvalues equal to zero. NSSD graphs are of importance in the theory of conductance of…

Combinatorics · Mathematics 2019-10-29 Umar Hayat , Mubasher Umer , Ivan Gutman , Bijan Davvaz , Álvaro Nolla de Celis

Weighted graphs are ubiquitous throughout biology, chemistry, and the social sciences, motivating the development of generative models for abstract weighted graph data using deep neural networks. However, most current deep generative models…

Machine Learning · Computer Science 2025-08-01 Richard Williams , Eric Nalisnick , Andrew Holbrook

In the realm of generative models for graphs, extensive research has been conducted. However, most existing methods struggle with large graphs due to the complexity of representing the entire joint distribution across all node pairs and…

Social and Information Networks · Computer Science 2024-05-15 Andreas Bergmeister , Karolis Martinkus , Nathanaël Perraudin , Roger Wattenhofer

Graphlets are subgraphs rooted at a fixed vertex. The number of occurrences of graphlets aligned to a particular vertex, called graphlet degree sequence (gds), gives a topological description of the surrounding of the analyzed vertex.…

Combinatorics · Mathematics 2026-01-01 David Hartman , Aneta Pokorná , Daniel Trlifaj , Lluís Vena

The formation of a viral capsid -- the highly-ordered protein shell that surrounds the genome of a virus -- is the canonical example of self-assembly. The capsids of many positive-sense RNA viruses spontaneously assemble from in vitro…

Soft Condensed Matter · Physics 2022-06-08 Rees F. Garmann , Aaron M. Goldfain , Vinothan N. Manoharan

Linkage maps are used to identify the location of genes responsible for traits and diseases. New sequencing techniques have created opportunities to substantially increase the density of genetic markers. Such revolutionary advances in…

Applications · Statistics 2018-04-04 Pariya Behrouzi , Ernst C. Wit

Polymer composites are ubiquitous in biology and industry alike, owing to their emergent desirable mechanical properties not attainable in single-species systems. At the same time, polymer topology has been shown to play a key role in…

This paper introduces a new family of reconstruction codes which is motivated by applications in DNA data storage and sequencing. In such applications, DNA strands are sequenced by reading some subset of their substrings. While previous…

Information Theory · Computer Science 2023-04-21 Yonatan Yehezkeally , Daniella Bar-Lev , Sagi Marcovich , Eitan Yaakobi

Let $G$ be a connected undirected graph on $n$ vertices with no loops but possibly multiedges. Given an arithmetical structure $(\textbf{r}, \textbf{d})$ on $G$, we describe a construction which associates to it a graph $G'$ on $n-1$…

Combinatorics · Mathematics 2021-06-10 Christopher Keyes , Tomer Reiter

The study of nonplanar drawings of graphs with restricted crossing configurations is a well-established topic in graph drawing, often referred to as beyond-planar graph drawing. One of the most studied types of drawings in this area are the…

In the Survivable Network Design Problem (SNDP), the input is an edge-weighted (di)graph $G$ and an integer $r_{uv}$ for every pair of vertices $u,v\in V(G)$. The objective is to construct a subgraph $H$ of minimum weight which contains…

Data Structures and Algorithms · Computer Science 2017-01-12 Manu Basavaraju , Pranabendu Misra , M. S. Ramanujan , Saket Saurabh

We propose a new strategy for robust high-quality self-assembly of non-trivial periodic structures out of patchy particles, and investigate it with Brownian Dynamics (BD) simulations. Its first element is the use of specific patch-patch and…

Soft Condensed Matter · Physics 2017-08-09 Niladri Patra , Alexei V. Tkachenko