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Related papers: Omni-DNA: A Unified Genomic Foundation Model for C…

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We present Junk DNA Hypothesis by adopting a novel task-centric angle for the pre-trained weights of large language models (LLMs). It has been believed that weights in LLMs contain significant redundancy, leading to the conception that a…

Machine Learning · Computer Science 2026-05-01 Lu Yin , Ajay Jaiswal , Shiwei Liu , Souvik Kundu , Zhangyang Wang

Next-generation multimodal foundation models capable of any-to-any cross-modal generation and multi-turn interaction will serve as core components of artificial general intelligence systems, playing a pivotal role in human-machine…

Computation and Language · Computer Science 2025-10-17 Run Luo , Xiaobo Xia , Lu Wang , Longze Chen , Renke Shan , Jing Luo , Min Yang , Tat-Seng Chua

Foundation models, such as Large Language Models (LLMs) or Large Vision Models (LVMs), have emerged as one of the most powerful tools in the respective fields. However, unlike text and image data, graph data do not have a definitive…

Machine Learning · Computer Science 2025-04-28 Lecheng Kong , Jiarui Feng , Hao Liu , Chengsong Huang , Jiaxin Huang , Yixin Chen , Muhan Zhang

Large language models applied to vast biological datasets have the potential to transform biology by uncovering disease mechanisms and accelerating drug development. However, current models are often siloed, trained separately on…

Current multimodal and multitask foundation models like 4M or UnifiedIO show promising results, but in practice their out-of-the-box abilities to accept diverse inputs and perform diverse tasks are limited by the (usually rather small)…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Roman Bachmann , Oğuzhan Fatih Kar , David Mizrahi , Ali Garjani , Mingfei Gao , David Griffiths , Jiaming Hu , Afshin Dehghan , Amir Zamir

We present Lunima-OmniLV (abbreviated as OmniLV), a universal multimodal multi-task framework for low-level vision that addresses over 100 sub-tasks across four major categories: image restoration, image enhancement, weak-semantic dense…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Yuandong Pu , Le Zhuo , Kaiwen Zhu , Liangbin Xie , Wenlong Zhang , Xiangyu Chen , Peng Gao , Yu Qiao , Chao Dong , Yihao Liu

Recently, Vision-Language Models (VLMs) have achieved remarkable progress in multimodal tasks, and multimodal instruction data serves as the foundation for enhancing VLM capabilities. Despite the availability of several open-source…

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

Interpreting transcriptomic data is one of the most common analytical tasks in modern biology. Yet most current models either consume expression profiles without producing natural-language biological explanations, or reason in language…

Collecting large amounts of real-world interaction data to train general robotic policies is often prohibitively expensive, thus motivating the use of simulation data. However, existing methods for data generation have generally focused on…

Machine Learning · Computer Science 2024-01-23 Lirui Wang , Yiyang Ling , Zhecheng Yuan , Mohit Shridhar , Chen Bao , Yuzhe Qin , Bailin Wang , Huazhe Xu , Xiaolong Wang

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

The development of effective machine learning methodologies for enhancing the efficiency and accuracy of clinical systems is crucial. Despite significant research efforts, managing a plethora of diversified clinical tasks and adapting to…

Computation and Language · Computer Science 2024-06-19 Yujiang Wu , Hongjian Song , Jiawen Zhang , Xumeng Wen , Shun Zheng , Jiang Bian

The task of understanding and interpreting the complex information encoded within genomic sequences remains a grand challenge in biological research and clinical applications. In this context, recent advancements in large language model…

Genomics · Quantitative Biology 2024-09-25 Qihang Zhao , Chi Zhang , Weixiong Zhang

Modern multimodal large language models (MLLMs) generate fluent responses from interleaved text, image, audio, and video inputs. However, identifying which input sources support each generated statement remains an open challenge. Existing…

Computation and Language · Computer Science 2026-04-16 Qianqi Yan , Yichen Guo , Ching-Chen Kuo , Shan Jiang , Hang Yin , Yang Zhao , Xin Eric Wang

We propose UniT, a Unified Transformer model to simultaneously learn the most prominent tasks across different domains, ranging from object detection to natural language understanding and multimodal reasoning. Based on the transformer…

Computer Vision and Pattern Recognition · Computer Science 2021-08-19 Ronghang Hu , Amanpreet Singh

Modeling genomic sequences faces two unsolved challenges: the information density varies widely across different regions, while there is no clearly defined minimum vocabulary unit. Relying on either four primitive bases or independently…

Genomics · Quantitative Biology 2025-11-20 Siyuan Li , Kai Yu , Anna Wang , Zicheng Liu , Chang Yu , Jingbo Zhou , Qirong Yang , Yucheng Guo , Xiaoming Zhang , Stan Z. Li

Recent advances in large language models (LLMs) have driven impressive progress in omni-modal understanding and generation. However, training omni-modal LLMs remains a significant challenge due to the heterogeneous model architectures…

Computation and Language · Computer Science 2025-08-08 Qianli Ma , Yaowei Zheng , Zhelun Shi , Zhongkai Zhao , Bin Jia , Ziyue Huang , Zhiqi Lin , Youjie Li , Jiacheng Yang , Yanghua Peng , Zhi Zhang , Xin Liu

The emergence of large multimodal models (LMMs) has brought significant advancements to pathology. Previous research has primarily focused on separately training patch-level and whole-slide image (WSI)-level models, limiting the integration…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Yuxuan Sun , Yixuan Si , Chenglu Zhu , Xuan Gong , Kai Zhang , Pingyi Chen , Ye Zhang , Zhongyi Shui , Tao Lin , Lin Yang

Large Language Models (LLMs) have advanced rapidly but face significant memory demands. While quantization has shown promise for LLMs, current methods typically require lengthy training to alleviate the performance degradation from…

Artificial Intelligence · Computer Science 2024-05-31 Ke Yi , Yuhui Xu , Heng Chang , Chen Tang , Yuan Meng , Tong Zhang , Jia Li

Tables stored in databases and tables which are present in web pages and articles account for a large part of semi-structured data that is available on the internet. It then becomes pertinent to develop a modeling approach with large…

Computation and Language · Computer Science 2023-10-03 Soumajyoti Sarkar , Leonard Lausen
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