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Alzheimer's disease (AD) is an irreversible and progressive brain disease that can be stopped or slowed down with medical treatment. Language changes serve as a sign that a patient's cognitive functions have been impacted, potentially…

Computation and Language · Computer Science 2018-04-19 Sweta Karlekar , Tong Niu , Mohit Bansal

Current automatic depression detection systems provide predictions directly without relying on the individual symptoms/items of depression as denoted in the clinical depression rating scales. In contrast, clinicians assess each item in the…

Autism spectrum disorder (ASD) can be defined as a neurodevelopmental disorder that affects how children interact, communicate and socialize with others. This disorder can occur in a broad spectrum of symptoms, with varying effects and…

Machine Learning · Computer Science 2021-10-08 Vikram Ramesh , Rida Assaf

Alzheimer's disease is a major cause of dementia. Its diagnosis requires accurate biomarkers that are sensitive to disease stages. In this respect, we regard probabilistic classification as a method of designing a probabilistic biomarker…

Machine Learning · Computer Science 2017-06-06 Murat Seckin Ayhan , Vijay Raghavan , Alzheimer's disease Neuroimaging Initiative

Speech impairments resulting from congenital disorders, such as cerebral palsy, down syndrome, or apert syndrome, as well as acquired brain injuries due to stroke, traumatic accidents, or tumors, present major challenges to automatic speech…

Audio and Speech Processing · Electrical Eng. & Systems 2026-03-17 Niclas Pokel , Pehuén Moure , Roman Boehringer , Shih-Chii Liu , Yingqiang Gao

With people living longer than ever, the number of cases with dementia such as Alzheimer's disease increases steadily. It affects more than 46 million people worldwide, and it is estimated that in 2050 more than 100 million will be…

Multimedia · Computer Science 2021-01-20 Mariona Caros , Maite Garolera , Petia Radeva , Xavier Giro-i-Nieto

Dementia is a progressive neurological disorder that profoundly affects the daily lives of older adults, impairing abilities such as verbal communication and cognitive function. Early diagnosis is essential for enhancing both lifespan and…

Computational Engineering, Finance, and Science · Computer Science 2023-11-07 Kaiying Lin , Peter Washington

This paper describes a multi-modal approach for the automatic detection of Alzheimer's disease proposed in the context of the INESC-ID Human Language Technology Laboratory participation in the ADReSS 2020 challenge. Our classification…

Audio and Speech Processing · Electrical Eng. & Systems 2020-06-01 Anna Pompili , Thomas Rolland , Alberto Abad

Background and Aim: Accurate classification of Magnetic Resonance Images (MRI) is essential to accurately predict Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) conversion. Meanwhile, deep learning has been successfully…

Computer Vision and Pattern Recognition · Computer Science 2021-09-03 Kshitiz Shrestha , Omar Hisham Alsadoon , Abeer Alsadoon , Tarik A. Rashid , Rasha S. Ali , P. W. C. Prasad , Oday D. Jerew

Dementia, a debilitating neurological condition affecting millions worldwide, presents significant diagnostic challenges. In this work, we introduce DEFORMISE, a novel DEep learning Framework for dementia diagnOsis of eldeRly patients using…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Nikolaos Ntampakis , Konstantinos Diamantaras , Ioanna Chouvarda , Vasileios Argyriou , Panagiotis Sarigianndis

Automatic Speech Recognition (ASR) is a critical component of any fully-automated speech-based dementia detection model. However, despite years of speech recognition research, little is known about the impact of ASR accuracy on dementia…

Computation and Language · Computer Science 2020-10-15 Aparna Balagopalan , Ksenia Shkaruta , Jekaterina Novikova

Early diagnosis of dementia, particularly in the prodromal stage (i.e., mild cognitive impairment, or MCI), has become a research and clinical priority but remains challenging. Automated analysis of the drawing process has been studied as a…

Signal Processing · Electrical Eng. & Systems 2022-11-17 Yasunori Yamada , Masatomo Kobayashi , Kaoru Shinkawa , Miyuki Nemoto , Miho Ota , Kiyotaka Nemoto , Tetsuaki Arai

Speech pause is an effective biomarker in dementia detection. Recent deep learning models have exploited speech pauses to achieve highly accurate dementia detection, but have not exploited the interpretability of speech pauses, i.e., what…

Computation and Language · Computer Science 2021-11-16 Youxiang Zhu , Bang Tran , Xiaohui Liang , John A. Batsis , Robert M. Roth

In recent years there has been a burgeoning interest in the use of computational methods to distinguish between elicited speech samples produced by patients with dementia, and those from healthy controls. The difference between perplexity…

Computation and Language · Computer Science 2020-06-30 Trevor Cohen , Serguei Pakhomov

Automated discourse analysis tools based on Natural Language Processing (NLP) aiming at the diagnosis of language-impairing dementias generally extract several textual metrics of narrative transcripts. However, the absence of sentence…

Computation and Language · Computer Science 2017-08-17 Marcos Vinícius Treviso , Christopher Shulby , Sandra Maria Aluísio

Alzheimer's disease (AD) progresses through distinct stages, from early mild cognitive impairment (EMCI) to late mild cognitive impairment (LMCI) and eventually to AD. Accurate identification of these stages, especially distinguishing LMCI…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Aswini Kumar Patra , Soraisham Elizabeth Devi , Tejashwini Gajurel

Alzheimer's disease is an untreatable, progressive brain disorder that slowly robs people of their memory, thinking abilities, and ultimately their capacity to complete even the most basic tasks. Among older adults, it is the most frequent…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 Nasser A Alsadhan

Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…

Audio and Speech Processing · Electrical Eng. & Systems 2021-09-28 Emil Svoboda , Tomáš Bořil , Jan Rusz , Tereza Tykalová , Dana Horáková , Charles R. G. Guttman , Krastan B. Blagoev , Hiroto Hatabu , Vlad I. Valtchinov

Healthcare datasets present many challenges to both machine learning and statistics as their data are typically heterogeneous, censored, high-dimensional and have missing information. Feature selection is often used to identify the…

Machine Learning · Computer Science 2022-07-06 Annette Spooner , Gelareh Mohammadi , Perminder S. Sachdev , Henry Brodaty , Arcot Sowmya

Dementia detection from spontaneous speech offers a scalable approach to cognitive screening, yet NLP systems remain predominantly English-centric. This limitation is especially acute in the Philippines, where Filipino-English…

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