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Mathematical models of infectious diseases, which are in principle analytically tractable, use two general approaches. The first approach, generally known as compartmental modeling, addresses the time evolution of disease propagation at the…

Populations and Evolution · Quantitative Biology 2010-09-16 Pierre-André Noël , Bahman Davoudi , Robert C. Brunham , Louis J. Dubé , Babak Pourbohloul

In robotics, diffusion models can capture multi-modal trajectories from demonstrations, making them a transformative approach in imitation learning. However, achieving optimal performance following this regiment requires a large-scale…

A novel predictive modeling framework for the spread of infectious diseases using high dimensional partial differential equations is developed and implemented. A scalar function representing the infected population is defined on a…

Populations and Evolution · Quantitative Biology 2020-07-06 Sashikumaar Ganesan , Deepak Subramani

Compartmental models of epidemics are widely used to forecast the effects of communicable diseases such as COVID-19 and to guide policy. Although it has long been known that such processes take place on social networks, the assumption of…

Physics and Society · Physics 2024-03-14 Samuel Johnson

Compartmental models are valuable tools for investigating infectious diseases. Researchers building such models typically begin with a simple structure where compartments correspond to individuals with different epidemiological statuses,…

Populations and Evolution · Quantitative Biology 2023-07-21 Darren Flynn-Primrose , Steven C. Walker , Michael Li , Benjamin M. Bolker , David J. D. Earn , Jonathan Dushoff

The COVID-19 pandemic has brought forth the importance of epidemic forecasting for decision makers in multiple domains, ranging from public health to the economy as a whole. While forecasting epidemic progression is frequently…

Machine Learning · Computer Science 2022-07-21 Alexander Rodríguez , Harshavardhan Kamarthi , Pulak Agarwal , Javen Ho , Mira Patel , Suchet Sapre , B. Aditya Prakash

Data describing human interactions often suffer from incomplete sampling of the underlying population. As a consequence, the study of contagion processes using data-driven models can lead to a severe underestimation of the epidemic risk.…

Physics and Society · Physics 2015-11-19 Mathieu Génois , Christian L. Vestergaard , Ciro Cattuto , Alain Barrat

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

Foundation models, including language models, e.g., GPT, and vision models, e.g., CLIP, have significantly advanced numerous biomedical tasks. Despite these advancements, the high inference latency and the "overthinking" issues in model…

Artificial Intelligence · Computer Science 2025-03-05 Zaifu Zhan , Shuang Zhou , Huixue Zhou , Zirui Liu , Rui Zhang

Epidemic models are always simplifications of real world epidemics. Which real world features to include, and which simplifications to make, depend both on the disease of interest and on the purpose of the modelling. In the present paper we…

Probability · Mathematics 2008-12-19 Tom Britton , David Lindenstrand

Forecasting infectious disease outbreaks is hard. Forecasting emerging infectious diseases with limited historical data is even harder. In this paper, we investigate ways to improve emerging infectious disease forecasting under operational…

We present EPITIME (EPidemic Integral models TIMe profile Explorer), a computational framework for the simulation of two classes of integral epidemic models: an age of infection model and an information dependent behavioural model. The…

Quantitative Methods · Quantitative Biology 2026-05-04 Bruno Buonomo , Eleonora Messina , Claudia Panico , Mario Pezzella , Gaetano Zanghirati

We introduce a methodology to guarantee safety against the spread of infectious diseases by viewing epidemiological models as control systems and by considering human interventions (such as quarantining or social distancing) as control…

Systems and Control · Electrical Eng. & Systems 2022-11-21 Tamas G. Molnar , Andrew W. Singletary , Gabor Orosz , Aaron D. Ames

The dynamics of contact networks and epidemics of infectious diseases often occur on comparable time scales. Ignoring one of these time scales may provide an incomplete understanding of the population dynamics of the infection process. We…

Populations and Evolution · Quantitative Biology 2021-02-09 Luis E C Rocha , Naoki Masuda

Infectious disease outbreaks recapitulate biology: they emerge from the multi-level interaction of hosts, pathogens, and their shared environment. As a result, predicting when, where, and how far diseases will spread requires a complex…

Physics and Society · Physics 2018-10-11 Samuel V. Scarpino , Giovanni Petri

We present a modelling framework for the spreading of epidemics on temporal networks from which both the individual-based and pair-based models can be recovered. The proposed temporal pair-based model that is systematically derived from…

Physics and Society · Physics 2020-11-17 Rory Humphries , Kieran Mulchrone , Jamie Tratalos , Simon More , Philipp Hövel

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

As an emergent infectious disease outbreak unfolds, public health response is reliant on information on key epidemiological quantities, such as transmission potential and serial interval. Increasingly, transmission models fit to incidence…

Populations and Evolution · Quantitative Biology 2015-06-29 Aaron A. King , Matthieu Domenech de Cellès , Felicia M. G. Magpantay , Pejman Rohani

The emergence and spread of deadly pandemics has repeatedly occurred throughout history, causing widespread infections and loss of life. The rapid spread of pandemics have made governments across the world adopt a range of actions,…

Populations and Evolution · Quantitative Biology 2024-01-15 Marianna Karapitta , Andreas Kasis , Charithea Stylianides , Kleanthis Malialis , Panayiotis Kolios

Advancing epidemic dynamics forecasting is vital for targeted interventions and safeguarding public health. Current approaches mainly fall into two categories: mechanism-based and data-driven models. Mechanism-based models are constrained…

Machine Learning · Computer Science 2025-08-05 Rui Sun , Chenghua Gong , Tianjun Gu , Yuhao Zheng , Jie Ding , Juyuan Zhang , Liming Pan , Linyuan Lü