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Deep generative models have recently been applied to physical systems governed by partial differential equations (PDEs), offering scalable simulation and uncertainty-aware inference. However, enforcing physical constraints, such as…
This study introduces a novel framework for joint reconstruction of the activity and the attenuation (JRAA) in positron emission tomography (PET) using diffusion posterior sampling (DPS). By leveraging diffusion models (DMs), this approach…
Recent advancements in generative models have revolutionized the field of artificial intelligence, enabling the creation of highly-realistic and detailed images. In this study, we propose a novel Mask Conditional Text-to-Image Generative…
Flow matching casts sample generation as learning a continuous-time velocity field that transports noise to data. Existing flow matching networks typically predict each point's velocity independently, considering only its location and time…
Zero-shot MRI reconstruction relies on generative priors, but single-modality unconditional priors produce hallucinations under severe ill-posedness. In many clinical workflows, complementary MRI acquisitions (e.g. high-quality structural…
Background: Cone-beam computed tomography (CBCT) plays a crucial role in image-guided radiotherapy, but artifacts and noise make them unsuitable for accurate dose calculation. Artificial intelligence methods have shown promise in enhancing…
Positron emission tomography (PET) imaging is an imaging modality for diagnosing a number of neurological diseases. In contrast to Magnetic Resonance Imaging (MRI), PET is costly and involves injecting a radioactive substance into the…
Magnetic resonance diffusion tensor imaging (DTI) is a critical tool for neural disease diagnosis. However, long scan time greatly hinders the widespread clinical use of DTI. To accelerate image acquisition, a feature-enhanced joint…
Fourier Ptychographic Microscopy (FPM) is a computational imaging technique that enables high-resolution imaging over a large field of view. However, its application in the biomedical field has been limited due to the long image…
Diffusion models (DMs) are capable of generating remarkably high-quality samples by iteratively denoising a random vector, a process that corresponds to moving along the probability flow ordinary differential equation (PF ODE).…
Multivariate count data are commonly encountered through high-throughput sequencing technologies in bioinformatics, text mining, or in sports analytics. Although the Poisson distribution seems a natural fit to these count data, its…
Multi-contrast Magnetic Resonance Imaging (MRI) generates multiple medical images with rich and complementary information for routine clinical use; however, it suffers from a long acquisition time. Recent works for accelerating MRI, mainly…
Anatomical structures such as blood vessels in contrast-enhanced CT (ceCT) images can be challenging to segment due to the variability in contrast medium diffusion. The combined use of ceCT and contrast-free (CT) CT images can improve the…
Diffusion models have exhibited exciting capabilities in generating images and are also very promising for video creation. However, the inference speed of diffusion models is limited by the slow sampling process, restricting its use cases.…
While generative modeling has achieved remarkable success on tasks like natural language-conditioned image generation, enabling model adaptation from example data points remains a relatively underexplored and challenging problem. To this…
Consistency Models (CMs) have made significant progress in accelerating the generation of diffusion models. However, their application to high-resolution, text-conditioned image generation in the latent space remains unsatisfactory. In this…
Continuous Conditional Diffusion Model (CCDM) is a diffusion-based framework designed to generate high-quality images conditioned on continuous regression labels. Although CCDM has demonstrated clear advantages over prior approaches across…
In medical image segmentation tasks, diffusion models have shown significant potential. However, mainstream diffusion models suffer from drawbacks such as multiple sampling times and slow prediction results. Recently, consistency models, as…
Photon-counting computed tomography (PCCT) has emerged as a promising imaging technique, enabling spectral imaging and material decomposition (MD). However, images typically suffer from a low signal-to-noise ratio (SNR) due to constraints…
Modern PET systems reach a spatial resolution of 3-10 mm. A disadvantage of this technique is the diffusion of the positron before its decay with a typical range of ca. 1 mm (depending on its energy). This motion and Compton scattering of…