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While model serving has unlocked unprecedented capabilities, the high cost of serving large-scale models continues to be a significant barrier to widespread accessibility and rapid innovation. Compiler optimizations have long driven…

Machine Learning · Computer Science 2026-02-05 Annabelle Sujun Tang , Christopher Priebe , Rohan Mahapatra , Lianhui Qin , Hadi Esmaeilzadeh

Well-designed prompts are crucial for enhancing Large language models' (LLMs) reasoning capabilities while aligning their outputs with task requirements across diverse domains. However, manually designed prompts require expertise and…

Computation and Language · Computer Science 2025-08-22 Jinyu Xiang , Jiayi Zhang , Zhaoyang Yu , Xinbing Liang , Fengwei Teng , Jinhao Tu , Fashen Ren , Xiangru Tang , Sirui Hong , Chenglin Wu , Yuyu Luo

Recent Large Language Models (LLMs) have significantly advanced natural language processing and automated decision-making. However, these models still encounter difficulties when performing complex reasoning tasks involving logical…

Computation and Language · Computer Science 2025-06-26 Yubo Dong , Hehe Fan

Modern optimization in experimental chemistry employs algorithmic search through black-box parameter spaces. Here we demonstrate that pre-trained knowledge in large language models (LLMs) fundamentally changes this paradigm. Using six fully…

Machine Learning · Computer Science 2025-10-29 Robert MacKnight , Jose Emilio Regio , Jeffrey G. Ethier , Luke A. Baldwin , Gabe Gomes

The memory challenges associated with training Large Language Models (LLMs) have become a critical concern, particularly when using the Adam optimizer. To address this issue, numerous memory-efficient techniques have been proposed, with…

Machine Learning · Computer Science 2025-02-12 Yiming Chen , Yuan Zhang , Yin Liu , Kun Yuan , Zaiwen Wen

This paper presents an integrated framework that combines traditional network optimization models with large language models (LLMs) to deliver interactive, explainable, and role-aware decision support for supply chain planning. The proposed…

Artificial Intelligence · Computer Science 2025-09-01 Saravanan Venkatachalam

Optimizing black-box functions is a fundamental problem in science and engineering. To solve this problem, many approaches learn a surrogate function that estimates the underlying objective from limited historical evaluations. Large…

Machine Learning · Computer Science 2025-10-23 Tung Nguyen , Aditya Grover

Optimizing instructions for large language models (LLMs) is critical for harnessing their full potential in complex and diverse tasks. However, relying solely on white-box approaches demands extensive computational resources and offers…

Computation and Language · Computer Science 2025-06-30 Yanwei Ren , Liu Liu , Baosheng Yu , Jiayan Qiu , Quan Chen

We present a novel framework for automated interior design that combines large language models (LLMs) with grid-based integer programming to jointly optimize room layout and furniture placement. Given a textual prompt, the LLM-driven agent…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Chucheng Xiang , Ruchao Bao , Biyin Feng , Wenzheng Wu , Zhongyuan Liu , Yirui Guan , Ligang Liu

Vision Language Models (VLMs) have demonstrated remarkable potential in multimodal reasoning, yet they inherently suffer from spatial blindness and logical hallucinations when interpreting densely structured engineering content, such as…

Multiagent Systems · Computer Science 2026-03-25 Guanyuan Pan , Shuai Wang , Yugui Lin , Tiansheng Zhou , Pietro Liò , Zhenxin Zhao , Yaqi Wang

Analog IC design is a bottleneck due to its reliance on experience and inefficient simulations, as traditional formulas fail in advanced nodes. Applying Large Language Models (LLMs) directly to this problem risks mere "guessing" without…

Hardware Architecture · Computer Science 2025-08-20 Jianqiu Chen , Siqi Li , Xu He

Algorithm design is crucial for effective problem-solving across various domains. The advent of Large Language Models (LLMs) has notably enhanced the automation and innovation within this field, offering new perspectives and promising…

Machine Learning · Computer Science 2026-01-06 Fei Liu , Yiming Yao , Ping Guo , Zhiyuan Yang , Zhe Zhao , Xi Lin , Xialiang Tong , Kun Mao , Zhichao Lu , Zhenkun Wang , Mingxuan Yuan , Qingfu Zhang

Automation is one of the cornerstones of contemporary material discovery. Bayesian optimization (BO) is an essential part of such workflows, enabling scientists to leverage prior domain knowledge into efficient exploration of a large…

Machine Learning · Computer Science 2024-05-30 Agustinus Kristiadi , Felix Strieth-Kalthoff , Marta Skreta , Pascal Poupart , Alán Aspuru-Guzik , Geoff Pleiss

Large Language Models (LLMs) exhibit remarkable generative capabilities, enabling the generation of valuable information. Despite these advancements, previous research found that LLMs sometimes struggle with adhering to specific constraints…

Artificial Intelligence · Computer Science 2024-02-27 Kaiwen Wei , Jingyuan Zhang , Hongzhi Zhang , Fuzheng Zhang , Di Zhang , Li Jin , Yue Yu

Large Language Models (LLMs) demonstrate robust capabilities across various fields, leading to a paradigm shift in LLM-enhanced Recommender System (RS). Research to date focuses on point-wise and pair-wise recommendation paradigms, which…

Information Retrieval · Computer Science 2024-09-30 Wen-Shuo Chao , Zhi Zheng , Hengshu Zhu , Hao Liu

To accelerate mechanical design and enhance design quality and innovation, we present a Multidisciplinary Design and Optimization (MDO) Agent driven by Large Language Models (LLMs). The agent semi-automates the end-to-end workflow by…

Human-Computer Interaction · Computer Science 2025-11-25 Bingkun Guo , Wentian Li , Xiaojian Liu , Jiaqi Luo , Zibin Yu , Dalong Dong , Shuyou Zhang , Yiming Zhang

Large language models (LLMs) are a promising venue for natural language understanding and generation. However, current LLMs are far from reliable: they are prone to generating non-factual information and, more crucially, to contradicting…

Computation and Language · Computer Science 2024-09-24 Diego Calanzone , Stefano Teso , Antonio Vergari

The integration of large language models (LLMs) into automated algorithm design has shown promising potential. A prevalent approach embeds LLMs within search routines to iteratively generate and refine candidate algorithms. However, most…

Machine Learning · Computer Science 2026-05-20 Fei Liu , Rui Zhang , Xi Lin , Zhichao Lu , Qingfu Zhang

Optimization problems are pervasive in sectors from manufacturing and distribution to healthcare. However, most such problems are still solved heuristically by hand rather than optimally by state-of-the-art solvers because the expertise…

Artificial Intelligence · Computer Science 2025-08-29 Ali AhmadiTeshnizi , Wenzhi Gao , Herman Brunborg , Shayan Talaei , Connor Lawless , Madeleine Udell

This paper investigates the capabilities of large language models (LLMs) in formulating and solving decision-making problems using mathematical programming. We first conduct a systematic review and meta-analysis of recent literature to…

Artificial Intelligence · Computer Science 2025-08-26 Mohammad J. Abdel-Rahman , Yasmeen Alslman , Dania Refai , Amro Saleh , Malik A. Abu Loha , Mohammad Yahya Hamed