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Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…
Semantic segmentation is essential for analysing anatomical features in biomedical research, yet a performance gap remains for Vision Transformers (ViTs) in the field, particularly for sparse, fine-structured, and low signal-to-noise…
Deep learning models suffer from opaqueness. For Convolutional Neural Networks (CNNs), current research strategies for explaining models focus on the target classes within the associated training dataset. As a result, the understanding of…
Vision Transformers are at the heart of the current surge of interest in foundation models for histopathology. They process images by breaking them into smaller patches following a regular grid, regardless of their content. Yet, not all…
Recent developments in high throughput profiling of individual neurons have spurred data driven exploration of the idea that there exist natural groupings of neurons referred to as cell types. The promise of this idea is that the immense…
Nowadays, pre-trained encoders are widely used in medical image segmentation due to their strong capability in extracting rich and generalized feature representations. However, existing methods often fail to fully leverage these features,…
Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated…
The significant molecular and pathological heterogeneity of glioblastoma, an aggressive brain tumor, complicates diagnosis and patient stratification. While traditional histopathological assessment remains the standard, deep learning offers…
Foundation models are widely employed in medical image analysis, due to their high adaptability and generalizability for downstream tasks. With the increasing number of foundation models being released, model selection has become an…
This study evaluates the generalisation capabilities of state-of-the-art histopathology foundation models on out-of-distribution multi-stain autoimmune Immunohistochemistry datasets. We compare 13 feature extractor models, including…
Recent progress in vision-language pretraining has enabled significant improvements to many downstream computer vision applications, such as classification, retrieval, segmentation and depth prediction. However, a fundamental capability…
Foundation models are increasingly developed in computational pathology (CPath) given their promise in facilitating many downstream tasks. While recent studies have evaluated task performance across models, less is known about the structure…
The rapid development of digital pathology and modern deep learning has facilitated the emergence of pathology foundation models that are expected to solve general pathology problems under various disease conditions in one unified model,…
We investigate how successful bias mitigation reshapes the embedding space of encoder-only and decoder-only foundation models, offering an internal audit of model behaviour through representational analysis. Using BERT and Llama2 as…
Deep learning has been effective for histology image analysis in digital pathology. However, many current deep learning approaches require large, strongly- or weakly-labeled images and regions of interest, which can be time-consuming and…
Foundation models such as CLIP have demonstrated exceptional zero- and few-shot transfer capabilities across diverse vision tasks. However, when fine-tuned for highly specialized biometric tasks, face recognition (FR), morphing attack…
Transformers are popular neural network models that use layers of self-attention and fully-connected nodes with embedded tokens. Vision Transformers (ViT) adapt transformers for image recognition tasks. In order to do this, the images are…
Vision transformers (ViTs) have significantly changed the computer vision landscape and have periodically exhibited superior performance in vision tasks compared to convolutional neural networks (CNNs). Although the jury is still out on…
Automated face recognition has made rapid strides over the past decade due to the unprecedented rise of deep neural network (DNN) models that can be trained for domain-specific tasks. At the same time, foundation models that are pretrained…
Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…