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The integration of Large Language Models (LLMs) into healthcare applications offers promising advancements in medical diagnostics, treatment recommendations, and patient care. However, the susceptibility of LLMs to adversarial attacks poses…

Artificial Intelligence · Computer Science 2024-12-18 Yifan Yang , Qiao Jin , Furong Huang , Zhiyong Lu

Security concerns related to Large Language Models (LLMs) have been extensively explored, yet the safety implications for Multimodal Large Language Models (MLLMs), particularly in medical contexts (MedMLLMs), remain insufficiently studied.…

Cryptography and Security · Computer Science 2024-08-22 Xijie Huang , Xinyuan Wang , Hantao Zhang , Yinghao Zhu , Jiawen Xi , Jingkun An , Hao Wang , Hao Liang , Chengwei Pan

We introduce the Adversarial Confusion Attack, a new class of threats against multimodal large language models (MLLMs). Unlike jailbreaks or targeted misclassification, the goal is to induce systematic disruption that makes the model…

Computation and Language · Computer Science 2025-12-02 Jakub Hoscilowicz , Artur Janicki

In the field of Medical Imaging, extensive research has been dedicated to leveraging its potential in uncovering critical diagnostic features in patients. Artificial Intelligence (AI)-driven medical diagnosis relies on sophisticated machine…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Xiaohui Chen , Tie Luo

Multi-modal large language models (MLLMs) have made significant progress, yet their safety alignment remains limited. Typically, current open-source MLLMs rely on the alignment inherited from their language module to avoid harmful…

Cryptography and Security · Computer Science 2025-04-15 Yanbo Wang , Jiyang Guan , Jian Liang , Ran He

Multimodal large language models (MLLMs), which bridge the gap between audio-visual and natural language processing, achieve state-of-the-art performance on several audio-visual tasks. Despite the superior performance of MLLMs, the scarcity…

Cryptography and Security · Computer Science 2025-06-16 Jinming Wen , Xinyi Wu , Shuai Zhao , Yanhao Jia , Yuwen Li

Vision-Language Models (VLMs) are increasingly used in clinical diagnostics, yet their robustness to adversarial attacks remains largely unexplored, posing serious risks. Existing medical attacks focus on secondary objectives such as model…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Akash Ghosh , Subhadip Baidya , Sriparna Saha , Xiuying Chen

Large language models (LLMs) demonstrate remarkable capabilities across various tasks. However, their deployment introduces significant risks related to intellectual property. In this context, we focus on model stealing attacks, where…

Cryptography and Security · Computer Science 2025-10-28 Kieu Dang , Phung Lai , NhatHai Phan , Yelong Shen , Ruoming Jin , Abdallah Khreishah

The success of deep learning in medical imaging applications has led several companies to deploy proprietary models in diagnostic workflows, offering monetized services. Even though model weights are hidden to protect the intellectual…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Ankita Raj , Harsh Swaika , Deepankar Varma , Chetan Arora

Machine learning (ML) is a rapidly developing area of medicine that uses significant resources to apply computer science and statistics to medical issues. ML's proponents laud its capacity to handle vast, complicated, and erratic medical…

Cryptography and Security · Computer Science 2025-01-21 Md Abdullah Al Nasim , Parag Biswas , Abdur Rashid , Kishor Datta Gupta , Roy George , Sovon Chakraborty , Khalil Shujaee

Deep neural networks (DNNs) have become popular for medical image analysis tasks like cancer diagnosis and lesion detection. However, a recent study demonstrates that medical deep learning systems can be compromised by carefully-engineered…

Computer Vision and Pattern Recognition · Computer Science 2021-07-05 Xingjun Ma , Yuhao Niu , Lin Gu , Yisen Wang , Yitian Zhao , James Bailey , Feng Lu

Adversarial attacks have been fairly explored for computer vision and vision-language models. However, the avenue of adversarial attack for the vision language segmentation models (VLSMs) is still under-explored, especially for medical…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Anjila Budathoki , Manish Dhakal

The discovery of adversarial examples has raised concerns about the practical deployment of deep learning systems. In this paper, we demonstrate that adversarial examples are capable of manipulating deep learning systems across three…

Cryptography and Security · Computer Science 2019-02-05 Samuel G. Finlayson , Hyung Won Chung , Isaac S. Kohane , Andrew L. Beam

Deep learning techniques have achieved superior performance in computer-aided medical image analysis, yet they are still vulnerable to imperceptible adversarial attacks, resulting in potential misdiagnosis in clinical practice. Oppositely,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Junhao Dong , Junxi Chen , Xiaohua Xie , Jianhuang Lai , Hao Chen

Malicious users attempt to replicate commercial models functionally at low cost by training a clone model with query responses. It is challenging to timely prevent such model-stealing attacks to achieve strong protection and maintain…

Cryptography and Security · Computer Science 2025-03-18 Jian-Ping Mei , Weibin Zhang , Jie Chen , Xuyun Zhang , Tiantian Zhu

Building advanced machine learning (ML) models requires expert knowledge and many trials to discover the best architecture and hyperparameter settings. Previous work demonstrates that model information can be leveraged to assist other…

Cryptography and Security · Computer Science 2023-02-24 Boyang Zhang , Xinlei He , Yun Shen , Tianhao Wang , Yang Zhang

Deep Neural Networks (DNNs) are susceptible to model stealing attacks, which allows a data-limited adversary with no knowledge of the training dataset to clone the functionality of a target model, just by using black-box query access. Such…

Machine Learning · Statistics 2019-11-19 Sanjay Kariyappa , Moinuddin K Qureshi

Large Language Models (LLMs) are being enhanced with the ability to use tools and to process multiple modalities. These new capabilities bring new benefits and also new security risks. In this work, we show that an attacker can use visual…

Cryptography and Security · Computer Science 2023-10-06 Xiaohan Fu , Zihan Wang , Shuheng Li , Rajesh K. Gupta , Niloofar Mireshghallah , Taylor Berg-Kirkpatrick , Earlence Fernandes

Adversarial reprogramming allows stealing computational resources by repurposing machine learning models to perform a different task chosen by the attacker. For example, a model trained to recognize images of animals can be reprogrammed to…

Computer Science and Game Theory · Computer Science 2022-11-08 Yang Zheng , Xiaoyi Feng , Zhaoqiang Xia , Xiaoyue Jiang , Maura Pintor , Ambra Demontis , Battista Biggio , Fabio Roli

Machine learning (ML) models used in medical imaging diagnostics can be vulnerable to a variety of privacy attacks, including membership inference attacks, that lead to violations of regulations governing the use of medical data and…

Cryptography and Security · Computer Science 2021-08-23 William Paul , Yinzhi Cao , Miaomiao Zhang , Phil Burlina
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