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Purpose: To develop a retrieval-augmented generation (RAG) system powered by LLaMA-4 109B for automated, protocol-aware, and interpretable evaluation of radiotherapy treatment plans. Methods and Materials: We curated a multi-protocol…

Current medical AI systems often fail to replicate real-world clinical reasoning, as they are predominantly trained and evaluated on static text and question-answer tasks. These tuning methods and benchmarks overlook critical aspects like…

Computation and Language · Computer Science 2026-02-24 Zijie Liu , Xinyu Zhao , Jie Peng , Zhuangdi Zhu , Qingyu Chen , Kaidi Xu , Xia Hu , Tianlong Chen

Deploying Large Language Model (LLM) applications, particularly those relying on Retrieval-Augmented Generation (RAG), remains challenging due to high computational demands, outdated knowledge bases, and the need to manually select optimal…

Retrieval augmented generation (RAG) systems provide a method for factually grounding the responses of a Large Language Model (LLM) by providing retrieved evidence, or context, as support. Guided by this context, RAG systems can reduce…

Information Retrieval · Computer Science 2025-09-05 Shakiba Amirshahi , Amin Bigdeli , Charles L. A. Clarke , Amira Ghenai

This study presents a systematic comparison of three approaches for the analysis of mental health text using large language models (LLMs): prompt engineering, retrieval augmented generation (RAG), and fine-tuning. Using LLaMA 3, we evaluate…

Computation and Language · Computer Science 2025-04-01 Arshia Kermani , Veronica Perez-Rosas , Vangelis Metsis

Retrieval-Augmented Generation (RAG) has emerged as a prominent method for incorporating domain knowledge into Large Language Models (LLMs). While RAG enhances response relevance by incorporating retrieved domain knowledge in the context,…

Computation and Language · Computer Science 2025-03-28 Kushagra Bhushan , Yatin Nandwani , Dinesh Khandelwal , Sonam Gupta , Gaurav Pandey , Dinesh Raghu , Sachindra Joshi

Large language models (LLMs) have significantly advanced the field of natural language generation. However, they frequently generate unverified outputs, which compromises their reliability in critical applications. In this study, we propose…

Computation and Language · Computer Science 2025-02-18 Alexandru Lecu , Adrian Groza , Lezan Hawizy

Background The increasing adoption of Artificial Intelligence (AI) in healthcare has sparked growing concerns about its environmental and ethical implications. Commercial Large Language Models (LLMs), such as ChatGPT and DeepSeek, require…

Artificial Intelligence · Computer Science 2025-06-26 Konstantinos Vrettos , Michail E. Klontzas

Retrieval Augmented Generation (RAG) is a technique used to augment Large Language Models (LLMs) with contextually relevant, time-critical, or domain-specific information without altering the underlying model parameters. However,…

Information Retrieval · Computer Science 2024-08-20 Laurent Mombaerts , Terry Ding , Adi Banerjee , Florian Felice , Jonathan Taws , Tarik Borogovac

Security applications are increasingly relying on large language models (LLMs) for cyber threat detection; however, their opaque reasoning often limits trust, particularly in decisions that require domain-specific cybersecurity knowledge.…

Cryptography and Security · Computer Science 2025-11-03 Arnabh Borah , Md Tanvirul Alam , Nidhi Rastogi

Recently, Large Language Models (LLMs) have been increasingly used to support various decision-making tasks, assisting humans in making informed decisions. However, when LLMs confidently provide incorrect information, it can lead humans to…

Information Retrieval · Computer Science 2025-10-16 Chaeyun Jang , Deukhwan Cho , Seanie Lee , Hyungi Lee , Juho Lee

Large Language Models (LLMs) have catalyzed significant advancements in Natural Language Processing (NLP), yet they encounter challenges such as hallucination and the need for domain-specific knowledge. To mitigate these, recent…

Computation and Language · Computer Science 2025-07-01 Yucheng Hu , Yuxing Lu

Large Language Models (LLMs) have made remarkable advancements in the field of natural language processing. However, their increasing size poses challenges in terms of computational cost. On the other hand, Small Language Models (SLMs) are…

Computation and Language · Computer Science 2023-08-03 Zhen Guo , Peiqi Wang , Yanwei Wang , Shangdi Yu

Natural Language Processing (NLP) and Voice Recognition agents are rapidly evolving healthcare by enabling efficient, accessible, and professional patient support while automating grunt work. This report serves as my self project wherein…

Audio and Speech Processing · Electrical Eng. & Systems 2025-02-21 Kabir Kumar

Large language models (LLMs) have shown remarkable capabilities in various natural language tasks and are increasingly being applied in healthcare domains. This work demonstrates a new LLM-powered disease risk assessment approach via…

Computation and Language · Computer Science 2024-09-24 Mohammad Amin Roshani , Xiangyu Zhou , Yao Qiang , Srinivasan Suresh , Steve Hicks , Usha Sethuraman , Dongxiao Zhu

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Retrieval-augmented generation (RAG) has proven highly effective in improving large language models (LLMs) across various domains. However, there is no benchmark specifically designed to assess the effectiveness of RAG in the legal domain,…

Computation and Language · Computer Science 2025-03-03 Haitao Li , Yifan Chen , Yiran Hu , Qingyao Ai , Junjie Chen , Xiaoyu Yang , Jianhui Yang , Yueyue Wu , Zeyang Liu , Yiqun Liu

Deploying Large Language Models (LLMs) for healthcare question answering requires robust methods to ensure accuracy and reliability. This work introduces Query-Based Retrieval Augmented Generation (QB-RAG), a framework for enhancing…

Machine Learning · Computer Science 2025-07-31 Eric Yang , Jonathan Amar , Jong Ha Lee , Bhawesh Kumar , Yugang Jia

Large language models (LLMs) have emerged as valuable tools for many natural language understanding tasks. In safety-critical applications such as healthcare, the utility of these models is governed by their ability to generate outputs that…

Computation and Language · Computer Science 2023-03-31 Varun Nair , Elliot Schumacher , Geoffrey Tso , Anitha Kannan

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

Computation and Language · Computer Science 2024-08-23 Xiaohan Wang , Xiaoyan Yang , Yuqi Zhu , Yue Shen , Jian Wang , Peng Wei , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang