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Machine learning applications, especially in the fields of me\-di\-cine and social sciences, are slowly being subjected to increasing scrutiny. Similarly to sample size planning performed in clinical and social studies, lawmakers and…

Methodology · Statistics 2023-01-16 Antoni Klorek , Karol Roszak , Izabela Szczech , Dariusz Brzezinski

Scoring systems are highly interpretable and widely used to evaluate time-to-event outcomes in healthcare research. However, existing time-to-event scores are predominantly created ad-hoc using a few manually selected variables based on…

Machine Learning · Computer Science 2024-06-11 Feng Xie , Yilin Ning , Han Yuan , Benjamin Alan Goldstein , Marcus Eng Hock Ong , Nan Liu , Bibhas Chakraborty

Survival analysis (SA) is an active field of research that is concerned with time-to-event outcomes and is prevalent in many domains, particularly biomedical applications. Despite its importance, SA remains challenging due to small-scale…

Machine Learning · Statistics 2022-02-16 Philipp Kopper , Simon Wiegrebe , Bernd Bischl , Andreas Bender , David Rügamer

The electronic health record (EHR) provides an unprecedented opportunity to build actionable tools to support physicians at the point of care. In this paper, we investigate survival analysis in the context of EHR data. We introduce deep…

Machine Learning · Statistics 2016-09-20 Rajesh Ranganath , Adler Perotte , Noémie Elhadad , David Blei

Joint models for longitudinal and survival data have gained a lot of attention in recent years, with the development of myriad extensions to the basic model, including those which allow for multivariate longitudinal data, competing risks…

Methodology · Statistics 2020-03-09 Katya Mauff , Ewout Steyerberg , Isabella Kardys , Eric Boersma , Dimitris Rizopoulos

In semi-supervised segmentation, capturing meaningful semantic structures from unlabeled data is essential. This is particularly challenging in histopathology image analysis, where objects are densely distributed. To address this issue, we…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Meilong Xu , Xiaoling Hu , Shahira Abousamra , Chen Li , Chao Chen

Conventional survival analysis approaches estimate risk scores or individualized time-to-event distributions conditioned on covariates. In practice, there is often great population-level phenotypic heterogeneity, resulting from (unknown)…

Machine Learning · Statistics 2020-03-03 Paidamoyo Chapfuwa , Chunyuan Li , Nikhil Mehta , Lawrence Carin , Ricardo Henao

Survival analysis studies and predicts the time of death, or other singular unrepeated events, based on historical data, while the true time of death for some instances is unknown. Survival trees enable the discovery of complex nonlinear…

Machine Learning · Computer Science 2024-01-10 Tim Huisman , Jacobus G. M. van der Linden , Emir Demirović

Synthetically generated data can improve privacy, fairness, and data accessibility; however, it can be challenging in specialized scenarios such as survival analysis. One key challenge in this setting is censoring, i.e., the timing of an…

Machine Learning · Statistics 2025-08-07 Mohd Ashhad , Ricardo Henao

The multivariate Hawkes process (MHP) is widely used for analyzing data streams that interact with each other, where events generate new events within their own dimension (via self-excitation) or across different dimensions (via…

Machine Learning · Computer Science 2024-11-01 Pio Calderon , Alexander Soen , Marian-Andrei Rizoiu

Evaluation is pivotal for refining Large Language Models (LLMs), pinpointing their capabilities, and guiding enhancements. The rapid development of LLMs calls for a lightweight and easy-to-use framework for swift evaluation deployment.…

Computation and Language · Computer Science 2024-07-23 Chaoqun He , Renjie Luo , Shengding Hu , Yuanqian Zhao , Jie Zhou , Hanghao Wu , Jiajie Zhang , Xu Han , Zhiyuan Liu , Maosong Sun

StocHy is a software tool for the quantitative analysis of discrete-time stochastic hybrid systems (SHS). StocHy accepts a high-level description of stochastic models and constructs an equivalent SHS model. The tool allows to (i) simulate…

Systems and Control · Electrical Eng. & Systems 2024-12-20 Nathalie Cauchi , Kurt Degiorgio , Alessandro Abate

Estimating risks or survival probabilities conditional on individual characteristics based on censored time-to-event data is a commonly faced task. This may be for the purpose of developing a prediction model or may be part of a wider…

Survival analysis is one of the most important fields of statistics in medicine and the biological sciences. In addition, the computational advances in the last decades have favoured the use of Bayesian methods in this context, providing a…

Applications · Statistics 2020-07-28 Danilo Alvares , Elena Lázaro , Virgilio Gómez-Rubio , Carmen Armero

A new modification of the explanation method SurvLIME called SurvLIME-Inf for explaining machine learning survival models is proposed. The basic idea behind SurvLIME as well as SurvLIME-Inf is to apply the Cox proportional hazards model to…

Machine Learning · Computer Science 2020-05-07 Lev V. Utkin , Maxim S. Kovalev , Ernest M. Kasimov

Over the last few years, with the growth of time-series collecting and storing, there has been a great demand for tools and software for temporal data engineering and modeling. This paper presents a generic workflow for time series data…

Computational Engineering, Finance, and Science · Computer Science 2023-10-24 Pejman Farhadi Ghalati , Andreas Schuppert

Python's dynamic type system, while offering significant flexibility and expressiveness, poses substantial challenges for static analysis and automated tooling, particularly in unannotated or partially annotated codebases. Existing type…

Software Engineering · Computer Science 2026-04-08 Ali Aman , Muhammad Asaduzzaman , Shaowei Wang

As Large Language Models increasingly power role-playing applications, simulating patients has become a valuable tool for training counselors and scaling therapeutic assessment. However, prior work is fragmented: existing approaches rely on…

Computation and Language · Computer Science 2026-02-13 Sahand Sabour , TszYam NG , Minlie Huang

Joint modeling of longitudinal and survival data has become increasingly important in medical research, particularly for understanding disease progression in chronic conditions where both repeated biomarker measurements and time-to-event…

Methodology · Statistics 2025-12-30 Nithisha Suryadevara , Vivek Reddy Srigiri

Difficulty replicating baselines, high computational costs, and required domain expertise create persistent barriers to clinical AI research. To address these challenges, we introduce PyHealth 2.0, an enhanced clinical deep learning toolkit…