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We consider design issues for toxicology studies when we have a continuous response and the true mean response is only known to be a member of a class of nested models. This class of non-linear models was proposed by toxicologists who were…

Statistics Theory · Mathematics 2010-11-29 Holger Dette , Andrey Pepelyshev , Piter Shpilev , Weng Kee Wong

With continuous progression of Moore's Law, integrated circuit (IC) device complexity is also increasing. Scanning Electron Microscope (SEM) image based extensive defect inspection and accurate metrology extraction are two main challenges…

Computer Vision and Pattern Recognition · Computer Science 2023-08-17 Vic De Ridder , Bappaditya Dey , Sandip Halder , Bartel Van Waeyenberge

We introduce an adjoint-based aerodynamic shape optimization framework that integrates a diffusion model trained on existing designs to learn a smooth manifold of aerodynamically viable shapes. This manifold is enforced as an equality…

Computational Engineering, Finance, and Science · Computer Science 2025-08-01 Long Chen , Emre Oezkaya , Jan Rottmayer , Nicolas R. Gauger , Zebang Shen , Yinyu Ye

Generative models have had a profound impact on vision and language, paving the way for a new era of multimodal generative applications. While these successes have inspired researchers to explore using generative models in science and…

Machine Learning · Computer Science 2023-06-05 Giorgio Giannone , Akash Srivastava , Ole Winther , Faez Ahmed

Diffusion models have attracted significant attention due to the remarkable ability to create content and generate data for tasks like image classification. However, the usage of diffusion models to generate the high-quality object…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Kai Chen , Enze Xie , Zhe Chen , Yibo Wang , Lanqing Hong , Zhenguo Li , Dit-Yan Yeung

We introduce discriminator guidance in the setting of Autoregressive Diffusion Models. The use of a discriminator to guide a diffusion process has previously been used for continuous diffusion models, and in this work we derive ways of…

Machine Learning · Computer Science 2024-09-24 Filip Ekström Kelvinius , Fredrik Lindsten

Calorimeter shower simulations are often the bottleneck in simulation time for particle physics detectors. A lot of effort is currently spent on optimizing generative architectures for specific detector geometries, which generalize poorly.…

Instrumentation and Detectors · Physics 2022-12-19 Junze Liu , Aishik Ghosh , Dylan Smith , Pierre Baldi , Daniel Whiteson

We propose DiffusionDet, a new framework that formulates object detection as a denoising diffusion process from noisy boxes to object boxes. During the training stage, object boxes diffuse from ground-truth boxes to random distribution, and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Shoufa Chen , Peize Sun , Yibing Song , Ping Luo

Detecting objects seamlessly blended into their surroundings represents a complex task for both human cognitive capabilities and advanced artificial intelligence algorithms. Currently, the majority of methodologies for detecting camouflaged…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Jianwei Zhao , Xin Li , Fan Yang , Qiang Zhai , Ao Luo , Zicheng Jiao , Hong Cheng

We present an end-to-end reconstruction algorithm to build particle candidates from detector hits in next-generation granular calorimeters similar to that foreseen for the high-luminosity upgrade of the CMS detector. The algorithm exploits…

Instrumentation and Detectors · Physics 2022-10-03 Shah Rukh Qasim , Nadezda Chernyavskaya , Jan Kieseler , Kenneth Long , Oleksandr Viazlo , Maurizio Pierini , Raheel Nawaz

The application of diffusion models in 3D LiDAR scene completion is limited due to diffusion's slow sampling speed. Score distillation accelerates diffusion sampling but with performance degradation, while post-training with direct policy…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 An Zhao , Shengyuan Zhang , Ling Yang , Zejian Li , Jiale Wu , Haoran Xu , AnYang Wei , Perry Pengyun GU , Lingyun Sun

Combinatorial Optimization (CO) problems are fundamentally important in numerous real-world applications across diverse industries, characterized by entailing enormous solution space and demanding time-sensitive response. Despite recent…

Artificial Intelligence · Computer Science 2025-06-10 Hang Zhao , Kexiong Yu , Yuhang Huang , Renjiao Yi , Chenyang Zhu , Kai Xu

Diffusion models have significantly advanced generative AI, but they encounter difficulties when generating complex combinations of multiple objects. As the final result heavily depends on the initial seed, accurately ensuring the desired…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Federico Betti , Lorenzo Baraldi , Lorenzo Baraldi , Rita Cucchiara , Nicu Sebe

In recent years, deep learning-based image compression, particularly through generative models, has emerged as a pivotal area of research. Despite significant advancements, challenges such as diminished sharpness and quality in…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Ryugo Morita , Hitoshi Nishimura , Ko Watanabe , Andreas Dengel , Jinjia Zhou

Inspired by Geoffrey Hinton emphasis on generative modeling, To recognize shapes, first learn to generate them, we explore the use of 3D diffusion models for object classification. Leveraging the density estimates from these models, our…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Nursena Koprucu , Meher Shashwat Nigam , Shicheng Xu , Biruk Abere , Gabriele Dominici , Andrew Rodriguez , Sharvaree Vadgama , Berfin Inal , Alberto Tono

We introduce an end-to-end computational framework that allows for hyperparameter optimization using the DeepHyper library, accelerated model training, and interpretable AI inference. The framework is based on state-of-the-art AI models…

Materials Science · Physics 2023-08-16 Hyun Park , Ruijie Zhu , E. A. Huerta , Santanu Chaudhuri , Emad Tajkhorshid , Donny Cooper

Future experiments at high energy $e^+e^-$ colliders will focus on extremely precise Standard Model measurements. Among the most important physics benchmarks, there is the capability to resolve the Higgs decays into W or Z pairs, in their…

High Energy Physics - Experiment · Physics 2023-11-17 Andrea Pareti

Direct preference optimization (DPO) has shown success in aligning diffusion models with human preference. Previous approaches typically assume a consistent preference label between final generations and noisy samples at intermediate steps,…

Machine Learning · Computer Science 2025-02-05 Jie Ren , Yuhang Zhang , Dongrui Liu , Xiaopeng Zhang , Qi Tian

Today, deep learning optimization is primarily driven by research focused on achieving high inference accuracy and reducing latency. However, the energy efficiency aspect is often overlooked, possibly due to a lack of sustainability mindset…

Networking and Internet Architecture · Computer Science 2024-06-11 Xiaolong Tu , Anik Mallik , Dawei Chen , Kyungtae Han , Onur Altintas , Haoxin Wang , Jiang Xie

Accurate simulation of physical processes is crucial for the success of modern particle physics. However, simulating the development and interaction of particle showers with calorimeter detectors is a time consuming process and drives the…

Instrumentation and Detectors · Physics 2021-05-28 Erik Buhmann , Sascha Diefenbacher , Engin Eren , Frank Gaede , Gregor Kasieczka , Anatolii Korol , Katja Krüger
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