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In this article, we introduce an infinite-dimensional deterministic SIS model which takes into account the heterogeneity of the infections and the social network among a large population. We study the long-time behavior of the dynamic. We…

Dynamical Systems · Mathematics 2020-06-16 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

This review maps developments in stochastic modeling, highlighting non-standard approaches and their applications to biology and epidemiology. It brings together four strands: (1) core models for systems that evolve with randomness; (2)…

Dynamical Systems · Mathematics 2025-10-24 Yassine Sabbar , Kottakkaran Sooppy Nisar

Motivated by the classical Susceptible-Infected-Recovered (SIR) epidemic models proposed by Kermack and Mckendrick, we consider a class of stochastic compartmental dynamical systems with a notion of partial ordering among the compartments.…

Populations and Evolution · Quantitative Biology 2019-01-03 Wasiur R. KhudaBukhsh , Boseung Choi , Eben Kenah , Grzegorz A. Rempala

The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

Clinical time series data from electronic health records and medical registries offer unprecedented opportunities to understand patient trajectories and inform medical decision-making. However, leveraging such data presents significant…

Machine Learning · Computer Science 2025-11-21 Muhammad Aslanimoghanloo , Ahmed ElGazzar , Marcel van Gerven

We introduce a minimal multiscale framework that links within-host virus dynamics to population-level SIRS epidemiology through explicit, bidirectional coupling. At the microscopic layer, a two variant quasispecies (master and mutant…

Dynamical Systems · Mathematics 2026-01-28 Juan C. Muñoz-Sánchez , J. Tomás Lázaro , Josep Sardanyés , Santiago F. Elena

Many real epidemics of an infectious disease are not straightforwardly super- or sub-critical, and the understanding of epidemic models that exhibit such complexity has been identified as a priority for theoretical work. We provide insights…

Probability · Mathematics 2018-02-23 Graham Brightwell , Thomas House , Malwina Luczak

In this paper, we are concerned with the stochastic susceptible-infectious-susceptible (SIS) epidemic model on the complete graph with $n$ vertices. This model has two parameters, which are the infection rate and the recovery rate. By…

Probability · Mathematics 2020-12-02 Huazheng Bu , Xiaofeng Xue

Infectious diseases are a threat for human health with tremendous impact on our society at large. The recent COVID-19 pandemic, caused by the SARS-CoV-2, is the latest example of a highly infectious disease ravaging the world, since late…

Populations and Evolution · Quantitative Biology 2021-09-17 Giacomo Cacciapaglia , Corentin Cot , Michele Della Morte , Stefan Hohenegger , Francesco Sannino , Shahram Vatani

We predict the future course of ongoing susceptible-infected-susceptible (SIS) epidemics on regular, Erd\H{o}s-R\'{e}nyi and Barab\'asi-Albert networks. It is known that the contact network influences the spread of an epidemic within a…

Populations and Evolution · Quantitative Biology 2021-11-11 Tanja Zerenner , Francesco Di Lauro , Masoumeh Dashti , Luc Berthouze , Istvan Z. Kiss

We study the diffusion of epidemics on networks that are partitioned into local communities. The gross structure of hierarchical networks of this kind can be described by a quotient graph. The rationale of this approach is that individuals…

Social and Information Networks · Computer Science 2016-01-19 Stefano Bonaccorsi , Stefania Ottaviano , Delio Mugnolo , Francesco De Pellegrini

Networks of contacts capable of spreading infectious diseases are often observed to be highly heterogeneous, with the majority of individuals having fewer contacts than the mean, and a significant minority having relatively very many…

Physics and Society · Physics 2016-12-21 César Parra-Rojas , Thomas House , Alan J. McKane

Two simple agent based models are often employed in epidemic studies: the susceptible-infected (SI) and the susceptible-infected-susceptible (SIS). Both models describe the time evolution of infectious diseases in networks in which vertices…

We study a stochastic spatial epidemic model where the $N$ individuals carry two features: a position and an infection state, interact and move in $\R^d$. In this Markovian model, the evolution of the infection states are described with the…

Probability · Mathematics 2021-11-05 Yen V. Vuong , Maxime Hauray , Etienne Pardoux

Biological systems commonly exhibit complex spatiotemporal patterns whose underlying generative mechanisms pose a significant analytical challenge. Traditional approaches to spatiodynamic inference rely on dimensionality reduction through…

Quantitative Methods · Quantitative Biology 2025-08-01 Jun Won Park , Kangyu Zhao , Sanket Rane

We consider a simple stochastic model for the spread of a disease caused by two virus strains in a closed homogeneously mixing population of size N. The spread of each strain in the absence of the other one is described by the stochastic…

Probability · Mathematics 2018-02-13 Fabio Lopes , Malwina Luczak

We analyze four models of epidemic spreading using a stochastic approach in which the primary stochastic variables are the numbers of individuals in each class. The stochastic approach is described by a master equation and the transition…

Statistical Mechanics · Physics 2020-10-28 Tânia Tomé , Mário J. de Oliveira

In the simple mean-field SIS and SIR epidemic models, infection is transmitted from infectious to susceptible members of a finite population by independent p-coin tosses. Spatial variants of these models are proposed, in which finite…

Probability · Mathematics 2007-07-26 Steven P. Lalley

The estimation from available data of parameters governing epidemics is a major challenge. In addition to usual issues (data often incomplete and noisy), epidemics of the same nature may be observed in several places or over different…

Methodology · Statistics 2021-09-20 Romain Narci , Maud Delattre , Catherine Larédo , Elisabeta Vergu

Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load…

Physics and Society · Physics 2022-05-10 Rossella Della Marca , Nadia Loy , Andrea Tosin