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Over the past years, deep learning capabilities and the availability of large-scale training datasets advanced rapidly, leading to breakthroughs in face recognition accuracy. However, these technologies are foreseen to face a major…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Fadi Boutros , Vitomir Struc , Julian Fierrez , Naser Damer

Real-world data often exhibits bias, imbalance, and privacy risks. Synthetic datasets have emerged to address these issues. This paradigm relies on generative AI models to generate unbiased, privacy-preserving data while maintaining…

Synthetic data serves as an alternative in training machine learning models, particularly when real-world data is limited or inaccessible. However, ensuring that synthetic data mirrors the complex nuances of real-world data is a challenging…

Machine Learning · Computer Science 2023-10-27 Lasse Hansen , Nabeel Seedat , Mihaela van der Schaar , Andrija Petrovic

The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic…

Machine Learning · Computer Science 2025-11-25 Youngjoon Lee , Seongmin Cho , Yehhyun Jo , Jinu Gong , Hyunjoo Jenny Lee , Joonhyuk Kang

Computer-aided tumor detection has shown great potential in enhancing the interpretation of over 80 million CT scans performed annually in the United States. However, challenges arise due to the rarity of CT scans with tumors, especially…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Qi Chen , Yuxiang Lai , Xiaoxi Chen , Qixin Hu , Alan Yuille , Zongwei Zhou

The digitization of medical records ushered in a new era of big data to clinical science, and with it the possibility that data could be shared, to multiply insights beyond what investigators could abstract from paper records. The need to…

Machine Learning · Computer Science 2021-06-03 Ofer Mendelevitch , Michael D. Lesh

Training medical AI algorithms requires large volumes of accurately labeled datasets, which are difficult to obtain in the real world. Synthetic images generated from deep generative models can help alleviate the data scarcity problem, but…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Xiaodan Xing , Yang Nan , Federico Felder , Simon Walsh , Guang Yang

AI requires extensive datasets, while medical data is subject to high data protection. Anonymization is essential, but poses a challenge for some regions, such as the head, as identifying structures overlap with regions of clinical…

As artificial intelligence (AI) becomes increasingly embedded in healthcare delivery, this chapter explores the critical aspects of developing reliable and ethical Clinical Decision Support Systems (CDSS). Beginning with the fundamental…

Artificial Intelligence · Computer Science 2025-02-18 Muhammet Alkan , Idris Zakariyya , Samuel Leighton , Kaushik Bhargav Sivangi , Christos Anagnostopoulos , Fani Deligianni

Synthetic Data is not new, but recent advances in Generative AI have raised interest in expanding the research toolbox, creating new opportunities and risks. This article provides a taxonomy of the full breadth of the Synthetic Data domain.…

Human-Computer Interaction · Computer Science 2024-08-29 Richard Timpone , Yongwei Yang

Synthetic data, which is artificially generated and intelligently mimicking or supplementing the real-world data, is increasingly used. The proliferation of AI agents and the adoption of synthetic data create a synthetic mirror that…

Computers and Society · Computer Science 2025-06-18 Marcelle Momha

Causal inference is essential for developing and evaluating medical interventions, yet real-world medical datasets are often difficult to access due to regulatory barriers. This makes synthetic data a potentially valuable asset that enables…

Machine Learning · Computer Science 2025-10-22 Harry Amad , Zhaozhi Qian , Dennis Frauen , Julianna Piskorz , Stefan Feuerriegel , Mihaela van der Schaar

With the advent of generative modeling techniques, synthetic data and its use has penetrated across various domains from unstructured data such as image, text to structured dataset modeling healthcare outcome, risk decisioning in financial…

Machine Learning · Computer Science 2021-05-11 Aman Gupta , Deepak Bhatt , Anubha Pandey

While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Luke W. Sagers , James A. Diao , Luke Melas-Kyriazi , Matthew Groh , Pranav Rajpurkar , Adewole S. Adamson , Veronica Rotemberg , Roxana Daneshjou , Arjun K. Manrai

The emergence of synthetic data for privacy protection, training data generation, or simply convenient access to quasi-realistic data in any shape or volume complicates the concept of ground truth. Synthetic data mimic real-world…

Computers and Society · Computer Science 2025-09-18 Dietmar Offenhuber

Artificial Intelligence (AI) is poised to transform healthcare delivery through revolutionary advances in clinical decision support and diagnostic capabilities. While human expertise remains foundational to medical practice, AI-powered…

Generating synthetic tabular health data is challenging, and evaluating their quality is equally, if not more, complex. This systematic review highlights the critical importance of rigorous evaluation of synthetic health data to ensure…

Machine Learning · Computer Science 2026-05-15 Nazia Nafis , Inaki Esnaola , Alvaro Martinez-Perez , Maria-Cruz Villa-Uriol , Venet Osmani

Mental health disorders are rising worldwide. However, the availability of trained clinicians has not scaled proportionally, leaving many people without adequate or timely support. To bridge this gap, recent studies have shown the promise…

Computation and Language · Computer Science 2025-08-19 Aishik Mandal , Prottay Kumar Adhikary , Hiba Arnaout , Iryna Gurevych , Tanmoy Chakraborty

Evidence-based medicine promises to improve the quality of healthcare by empowering medical decisions and practices with the best available evidence. The rapid growth of medical evidence, which can be obtained from various sources, poses a…

For sharing privacy-sensitive data, de-identification is commonly regarded as adequate for safeguarding privacy. Synthetic data is also being considered as a privacy-preserving alternative. Recent successes with numerical and tabular data…

Computation and Language · Computer Science 2025-03-05 Atiquer Rahman Sarkar , Yao-Shun Chuang , Noman Mohammed , Xiaoqian Jiang