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Deformable image registration is a fundamental task in medical image analysis, aiming to establish a dense and non-linear correspondence between a pair of images. Previous deep-learning studies usually employ supervised neural networks to…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Jun Zhang

Deep Learning in Image Registration (DLIR) methods have been tremendously successful in image registration due to their speed and ability to incorporate weak label supervision at training time. However, existing DLIR methods forego many of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Rohit Jena , Pratik Chaudhari , James C. Gee

Learning maps between data samples is fundamental. Applications range from representation learning, image translation and generative modeling, to the estimation of spatial deformations. Such maps relate feature vectors, or map between…

Computer Vision and Pattern Recognition · Computer Science 2021-06-18 Hastings Greer , Roland Kwitt , Francois-Xavier Vialard , Marc Niethammer

Affine image registration is a cornerstone of medical image analysis. While classical algorithms can achieve excellent accuracy, they solve a time-consuming optimization for every image pair. Deep-learning (DL) methods learn a function that…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Malte Hoffmann , Andrew Hoopes , Douglas N. Greve , Bruce Fischl , Adrian V. Dalca

We present VoxelMorph, a fast learning-based framework for deformable, pairwise medical image registration. Traditional registration methods optimize an objective function for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

This paper presents a novel predictive model, MetaMorph, for metamorphic registration of images with appearance changes (i.e., caused by brain tumors). In contrast to previous learning-based registration methods that have little or no…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Jian Wang , Jiarui Xing , Jason Druzgal , William M. Wells , Miaomiao Zhang

Learning-based deformable image registration (DIR) accelerates alignment by amortizing traditional optimization via neural networks. Label supervision further enhances accuracy, enabling efficient and precise nonlinear alignment of unseen…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Hang Zhang , Xiang Chen , Renjiu Hu , Rongguang Wang , Jinwei Zhang , Min Liu , Yaonan Wang , Gaolei Li , Xinxing Cheng , Jinming Duan

One aim of dimensionality reduction is to discover the main factors that explain the data, and as such is paramount to many applications. When working with high dimensional data, autoencoders offer a simple yet effective approach to learn…

Machine Learning · Computer Science 2025-08-29 Benjamin Couéraud , Vikram Sunkara , Christof Schütte

Deformable image registration plays an essential role in various medical image tasks. Existing deep learning-based deformable registration frameworks primarily utilize convolutional neural networks (CNNs) or Transformers to learn features…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Jiong Wu , Kuang Gong

Anatomically plausible image registration often requires volumetric preservation. Previous approaches to incompressible image registration have exploited relaxed constraints, ad hoc optimisation methods or practically intractable…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Lucas Fidon , Michael Ebner , Luis C. Garcia-Peraza-Herrera , Marc Modat , Sebastien Ourselin , Tom Vercauteren

Diffeomorphic image registration is crucial for various medical imaging applications because it can preserve the topology of the transformation. This study introduces DCCNN-LSTM-Reg, a learning framework that evolves dynamically and learns…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Jinqiu Deng , Ke Chen , Mingke Li , Daoping Zhang , Chong Chen , Alejandro F. Frangi , Jianping Zhang

Diffeomorphic deformable image registration is crucial in many medical image studies, as it offers unique, special properties including topology preservation and invertibility of the transformation. Recent deep learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Tony C. W. Mok , Albert C. S. Chung

Medical image segmentation models are typically optimised with voxel-wise losses that constrain predictions only in the output space. This leaves latent feature representations largely unconstrained, potentially limiting generalisation. We…

Image and Video Processing · Electrical Eng. & Systems 2026-03-02 Puru Vaish , Amin Ranem , Felix Meister , Tobias Heimann , Christoph Brune , Jelmer M. Wolterink

Deformable image registration plays a fundamental role in medical image analysis by enabling spatial alignment of anatomical structures across subjects. While recent deep learning-based approaches have significantly improved computational…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jiaqi Shang , Haojin Wu , Yinyi Lai , Zongyu Li , Chenghao Zhang , Jia Guo

Numerous regularization methods for deformable image registration aim at enforcing smooth transformations, but are difficult to tune-in a priori and lack a clear physical basis. Physically inspired strategies have emerged, offering a sound…

Image and Video Processing · Electrical Eng. & Systems 2023-12-27 Pablo Alvarez , Stéphane Cotin

We present HyperMorph, a learning-based strategy for deformable image registration that removes the need to tune important registration hyperparameters during training. Classical registration methods solve an optimization problem to find a…

Computer Vision and Pattern Recognition · Computer Science 2021-05-06 Andrew Hoopes , Malte Hoffmann , Bruce Fischl , John Guttag , Adrian V. Dalca

Proper regularization is crucial in inverse problems to achieve high-quality reconstruction, even with an ill-conditioned measurement system. This is particularly true for three-dimensional photoacoustic tomography, which is computationally…

Optimization and Control · Mathematics 2024-09-26 Chao Wang , Alexandre H. Thiery

Equivariant and invariant deep learning models have been developed to exploit intrinsic symmetries in data, demonstrating significant effectiveness in certain scenarios. However, these methods often suffer from limited representation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Yulu Bai , Jiahong Fu , Qi Xie , Deyu Meng

Longitudinal imaging allows for the study of structural changes over time. One approach to detecting such changes is by non-linear image registration. This study introduces Multi-Session Temporal Registration (MUSTER), a novel method that…

Temporal echocardiography image registration is a basis for clinical quantifications such as cardiac motion estimation, myocardial strain assessments, and stroke volume quantifications. In past studies, deep learning image registration…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Md. Kamrul Hasan , Haobo Zhu , Guang Yang , Choon Hwai Yap