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Longitudinal imaging forms an essential component in the management and follow-up of many medical conditions. The presence of lesion changes on serial imaging can have significant impact on clinical decision making, highlighting the…

Single image super-resolution (SISR) is a very popular topic nowadays, which has both research value and practical value. In daily life, we crop a large image into sub-images to do super-resolution and then merge them together. Although…

Lung cancer is highly lethal, emphasizing the critical need for early detection. However, identifying lung nodules poses significant challenges for radiologists, who rely heavily on their expertise for accurate diagnosis. To address this…

In image segmentation, there is often more than one plausible solution for a given input. In medical imaging, for example, experts will often disagree about the exact location of object boundaries. Estimating this inherent uncertainty and…

For image super-resolution (SR), bridging the gap between the performance on synthetic datasets and real-world degradation scenarios remains a challenge. This work introduces a novel "Low-Res Leads the Way" (LWay) training framework,…

Averaging neural network weights sampled by a backbone stochastic gradient descent (SGD) is a simple yet effective approach to assist the backbone SGD in finding better optima, in terms of generalization. From a statistical perspective,…

High-quality magnetic resonance (MR) image, i.e., with near isotropic voxel spacing, is desirable in various scenarios of medical image analysis. However, many MR acquisitions use large inter-slice spacing in clinical practice. In this…

Segmenting the boundary between tumor and healthy tissue during surgical cancer resection poses a significant challenge. In recent years, Hyperspectral Imaging (HSI) combined with Machine Learning (ML) has emerged as a promising solution.…

Skin lesion segmentation is a crucial method for identifying early skin cancer. In recent years, both convolutional neural network (CNN) and Transformer-based methods have been widely applied. Moreover, combining CNN and Transformer…

For nonrigid image registration, matching the particular structures (or the outliers) that have missing correspondence and/or local large deformations, can be more difficult than matching the common structures with small deformations in the…

Automated surface segmentation of retinal layer is important and challenging in analyzing optical coherence tomography (OCT). Recently, many deep learning based methods have been developed for this task and yield remarkable performance.…

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Longitudinal imaging is able to capture both static anatomical structures and dynamic changes in disease progression towards earlier and better patient-specific pathology management. However, conventional approaches for detecting diabetic…

Deep learning-based Generative Models have the potential to convert low-resolution CT images into high-resolution counterparts without long acquisition times and increased radiation exposure in thin-slice CT imaging. However, procuring…

Structural magnetic resonance imaging (sMRI) can identify subtle brain changes due to its high contrast for soft tissues and high spatial resolution. It has been widely used in diagnosing neurological brain diseases, such as Alzheimer…

Volumetric lesion segmentation via medical imaging is a powerful means to precisely assess multiple time-point lesion/tumor changes. Because manual 3D segmentation is prohibitively time consuming and requires radiological experience,…

The Sharp/van der Heijde (SvdH) score has been widely used in clinical trials to quantify radiographic damage in Rheumatoid Arthritis (RA), but its complexity has limited its adoption in routine clinical practice. To address the…

Multiple Sclerosis (MS) is an autoimmune disease that leads to lesions in the central nervous system. Magnetic resonance (MR) images provide sufficient imaging contrast to visualize and detect lesions, particularly those in the white…

Ultrasound imaging is crucial for evaluating organ morphology and function, yet depth adjustment can degrade image quality and field-of-view, presenting a depth-dependent dilemma. Traditional interpolation-based zoom-in techniques often…

Robot-assisted surgery is an emerging technology which has undergone rapid growth with the development of robotics and imaging systems. Innovations in vision, haptics and accurate movements of robot arms have enabled surgeons to perform…