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Microscopy imaging techniques are instrumental for characterization and analysis of biological structures. As these techniques typically render 3D visualization of cells by stacking 2D projections, issues such as out-of-plane excitation and…

Image and Video Processing · Electrical Eng. & Systems 2023-02-16 Amirkoushyar Ziabari , Derek C. Rose , Abbas Shirinifard , David Solecki

The ability to extrapolate gene expression dynamics in living single cells requires robust cell segmentation, and one of the challenges is the amorphous or irregularly shaped cell boundaries. To address this issue, we modified the U-Net…

Quantitative Methods · Quantitative Biology 2020-01-17 Nanyan Zhu , Chen Liu , Zakary S. Singer , Tal Danino , Andrew F. Laine , Jia Guo

Segmentation, or the outlining of objects within images, is a critical step in the measurement and analysis of cells within microscopy images. While improvements continue to be made in tools that rely on classical methods for segmentation,…

Quantitative Methods · Quantitative Biology 2024-03-15 Nodar Gogoberidze , Beth A. Cimini

For many years, image over-segmentation into superpixels has been essential to computer vision pipelines, by creating homogeneous and identifiable regions of similar sizes. Such constrained segmentation problem would require a clear…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Rémi Giraud , Michaël Clément

Segmentation in 3D scans is playing an increasingly important role in current clinical practice supporting diagnosis, tissue quantification, or treatment planning. The current 3D approaches based on convolutional neural networks usually…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Alexey Novikov , David Major , Maria Wimmer , Dimitrios Lenis , Katja Bühler

We present MeshSegmenter, a simple yet effective framework designed for zero-shot 3D semantic segmentation. This model successfully extends the powerful capabilities of 2D segmentation models to 3D meshes, delivering accurate 3D…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Ziming Zhong , Yanxu Xu , Jing Li , Jiale Xu , Zhengxin Li , Chaohui Yu , Shenghua Gao

Epithelial cells form diverse structures from squamous spherical organoids to densely packed pseudostratified tissues. Quantification of cellular properties in these contexts requires high-resolution deep imaging and computational…

Quantitative Methods · Quantitative Biology 2025-02-03 G. Paci , P. Vicente-Munuera , I. Fernandez-Mosquera , A. Miranda , K. Lau , Q. Zhang , R. Barrientos , Y. Mao

A systematic analysis of the cell behavior requires automated approaches for cell segmentation and tracking. While deep learning has been successfully applied for the task of cell segmentation, there are few approaches for simultaneous cell…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Katharina Löffler , Ralf Mikut

We combine confocal imaging, microfluidics and image analysis to record 3D-images of cells in flow. This enables us to recover the full 3D representation of several hundred living cells per minute. Whereas 3D confocal imaging has thus far…

Fluid Dynamics · Physics 2017-09-19 S. Quint , A. F. Christ , A. Guckenberger , S. Himbert , L. Kaestner , S. Gekle , C. Wagner

Volumetric cell segmentation in fluorescence microscopy images is important to study a wide variety of cellular processes. Applications range from the analysis of cancer cells to behavioral studies of cells in the embryonic stage. Like in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Royden Wagner , Karl Rohr

Robots operating in unstructured environments often require accurate and consistent object-level representations. This typically requires segmenting individual objects from the robot's surroundings. While recent large models such as Segment…

Robotics · Computer Science 2025-04-07 Haozhan Tang , Tianyi Zhang , Oliver Kroemer , Matthew Johnson-Roberson , Weiming Zhi

We propose a new supervized learning framework for oversegmenting 3D point clouds into superpoints. We cast this problem as learning deep embeddings of the local geometry and radiometry of 3D points, such that the border of objects presents…

Computer Vision and Pattern Recognition · Computer Science 2019-04-04 Loic Landrieu , Mohamed Boussaha

Towards holistic understanding of 3D scenes, a general 3D segmentation method is needed that can segment diverse objects without restrictions on object quantity or categories, while also reflecting the inherent hierarchical structure. To…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Haiyang Ying , Yixuan Yin , Jinzhi Zhang , Fan Wang , Tao Yu , Ruqi Huang , Lu Fang

Deep learning has proven to yield fast and accurate predictions of quantum-chemical properties to accelerate the discovery of novel molecules and materials. As an exhaustive exploration of the vast chemical space is still infeasible, we…

Machine Learning · Statistics 2020-01-10 Niklas W. A. Gebauer , Michael Gastegger , Kristof T. Schütt

Image segmentation is a critical step in computational biomedical image analysis, typically evaluated using metrics like the Dice coefficient during training and validation. However, in clinical settings without manual annotations,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Sikha O K , Meritxell Riera-Marín , Adrian Galdran , Javier García Lopez , Julia Rodríguez-Comas , Gemma Piella , Miguel A. González Ballester

Profiling cellular phenotypes from microscopic imaging can provide meaningful biological information resulting from various factors affecting the cells. One motivating application is drug development: morphological cell features can be…

Machine Learning · Statistics 2019-06-19 Gil Tabak , Minjie Fan , Samuel J. Yang , Stephan Hoyer , Geoff Davis

The lack of fine-grained 3D shape segmentation data is the main obstacle to developing learning-based 3D segmentation techniques. We propose an effective semi-supervised method for learning 3D segmentations from a few labeled 3D shapes and…

Computer Vision and Pattern Recognition · Computer Science 2022-04-21 Chun-Yu Sun , Yu-Qi Yang , Hao-Xiang Guo , Peng-Shuai Wang , Xin Tong , Yang Liu , Heung-Yeung Shum

We present a novel method for characterizing the microstructure of a material from volumetric datasets such as 3D image data from computed tomography (CT). The method is based on a new statistical model for the distribution of voxel…

Materials Science · Physics 2021-01-06 Elise Otterlei Brenne , Vedrana Andersen Dahl , Peter Stanley Jørgensen

In this paper, we introduce and study a novel segmentation method for 4D images based on surface evolution governed by a nonlinear partial differential equation, the generalized subjective surface equation. The new method uses 4D digital…

Numerical Analysis · Mathematics 2022-06-30 Markjoe Olunna Uba , Karol Mikula , Seol Ah Park

Open-vocabulary 3D semantic segmentation aims to segment arbitrary categories beyond the training set. Existing methods predominantly rely on distilling knowledge from 2D open-vocabulary models. However, aligning 3D features to the 2D…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Xujing Tao , Chuxin Wang , Yubo Ai , Zhixin Cheng , Zhuoyuan Li , Liangsheng Liu , Yujia Chen , Xinjun Li , Qiao Li , Wenfei Yang , Tianzhu Zhang