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Agentic retrieval-augmented reasoning pipelines are increasingly used to structure how large language models (LLMs) incorporate external evidence in clinical decision support. These systems iteratively retrieve curated domain knowledge and…

Agent-based simulation is crucial for modeling complex human behavior, yet traditional approaches require extensive domain knowledge and large datasets. In data-scarce healthcare settings where historic and counterfactual data are limited,…

Artificial Intelligence · Computer Science 2025-04-01 Sarah Martinson , Lingkai Kong , Cheol Woo Kim , Aparna Taneja , Milind Tambe

LLM-based agents have demonstrated strong potential for autonomous machine learning, yet their applicability to health data remains limited. Existing systems often struggle to generalize across heterogeneous health data modalities, rely…

Artificial Intelligence · Computer Science 2026-02-03 Tong Xia , Weibin Li , Gang Liu , Yong Li

Unstructured notes within the electronic health record (EHR) contain rich clinical information vital for cancer treatment decision making and research, yet reliably extracting structured oncology data remains challenging due to extensive…

Purpose: To develop and evaluate an automated system for extracting structured clinical information from unstructured radiology and pathology reports using open-weights large language models (LMs) and retrieval augmented generation (RAG),…

Large language models (LLMs) have shown promise in medical domains, but their ability to handle specialized neurological reasoning requires systematic evaluation. We developed a comprehensive benchmark using 305 questions from Israeli Board…

Information Retrieval · Computer Science 2025-08-21 Moran Sorka , Alon Gorenshtein , Dvir Aran , Shahar Shelly

Large language model (LLM) agents are increasingly deployed in structured biomedical data environments, yet they often produce fluent but overconfident outputs when reasoning over complex multi-table data. We introduce an uncertainty-aware…

Large language models (LLMs) have exhibited remarkable capabilities across diverse open-domain tasks, yet their application in specialized domains such as civil engineering remains largely unexplored. This paper starts bridging this gap by…

Computation and Language · Computer Science 2025-07-08 Jiachen Liu , Ziheng Geng , Ran Cao , Lu Cheng , Paolo Bocchini , Minghui Cheng

Background: Structured information extraction from unstructured histopathology reports facilitates data accessibility for clinical research. Manual extraction by experts is time-consuming and expensive, limiting scalability. Large language…

Large language models (LLMs) show promise for healthcare question answering, but clinical use is limited by weak verification, insufficient evidence grounding, and unreliable confidence signalling. We propose a multi-agent medical QA…

Computation and Language · Computer Science 2026-02-17 Naeimeh Nourmohammadi , Md Meem Hossain , The Anh Han , Safina Showkat Ara , Zia Ush Shamszaman

As Large Language Model (LLM) agents are increasingly deployed in open-ended domains like software engineering, they frequently encounter underspecified instructions that lack crucial context. While human developers naturally resolve…

Computation and Language · Computer Science 2026-03-30 Nicholas Edwards , Sebastian Schuster

While Language Agents have achieved promising success by placing Large Language Models at the core of a more versatile design that dynamically interacts with the external world, the existing approaches neglect the notion of uncertainty…

Computation and Language · Computer Science 2024-05-31 Jiuzhou Han , Wray Buntine , Ehsan Shareghi

Automatic conversion of free-text radiology reports into structured data using Natural Language Processing (NLP) techniques is crucial for analyzing diseases on a large scale. While effective for tasks in widely spoken languages like…

Computation and Language · Computer Science 2024-05-24 Liam Hazan , Gili Focht , Naama Gavrielov , Roi Reichart , Talar Hagopian , Mary-Louise C. Greer , Ruth Cytter Kuint , Dan Turner , Moti Freiman

Purpose: This study aims to evaluate the effectiveness of large language models (LLMs) in automating disease annotation of CT radiology reports. We compare a rule-based algorithm (RBA), RadBERT, and three lightweight open-weight LLMs for…

Radiology reports are invaluable for clinical decision-making and hold great potential for automated analysis when structured into machine-readable formats. These reports often contain uncertainty, which we categorize into two distinct…

Computation and Language · Computer Science 2026-03-02 Paloma Rabaey , Jong Hak Moon , Jung-Oh Lee , Min Gwan Kim , Hangyul Yoon , Thomas Demeester , Edward Choi

Automating radiology report generation poses a dual challenge: building clinically reliable systems and designing rigorous evaluation protocols. We introduce a multi-agent reinforcement learning framework that serves as both a benchmark and…

Artificial Intelligence · Computer Science 2025-09-23 Ahmed T. Elboardy , Ghada Khoriba , Essam A. Rashed

The application of Large Language Models (LLMs) in healthcare is expanding rapidly, with one potential use case being the translation of formal medical reports into patient-legible equivalents. Currently, LLM outputs often need to be edited…

Multiagent Systems · Computer Science 2024-08-06 Malavikha Sudarshan , Sophie Shih , Estella Yee , Alina Yang , John Zou , Cathy Chen , Quan Zhou , Leon Chen , Chinmay Singhal , George Shih

We present an automatic large language model (LLM) conversion approach that produces uncertainty-aware LLMs capable of estimating uncertainty with every prediction. Our approach is model- and data-agnostic, is computationally-efficient, and…

Large language models (LLMs) show promise for extracting information from Electronic Health Records (EHR) and supporting clinical decisions. However, deployment in clinical settings faces challenges due to hallucination risks. We propose…

Artificial Intelligence · Computer Science 2025-08-27 Yongwoo Song , Minbyul Jeong , Mujeen Sung

Extracting structured clinical information from radiology reports is challenging, especially in low-resource languages. This is pronounced in Crohn's disease, with sparsely represented multi-organ findings. We developed Hierarchical…

Computation and Language · Computer Science 2025-09-08 Zvi Badash , Hadas Ben-Atya , Naama Gavrielov , Liam Hazan , Gili Focht , Ruth Cytter-Kuint , Talar Hagopian , Dan Turner , Moti Freiman
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