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Alzheimer's Disease (AD) ravages the cognitive ability of more than 5 million Americans and creates an enormous strain on the health care system. This paper proposes a machine learning predictive model for AD development without medical…

Quantitative Methods · Quantitative Biology 2020-06-17 Courtney Cochrane , David Castineira , Nisreen Shiban , Pavlos Protopapas

Premise. Patterns of electrical brain activity recorded via electroencephalography (EEG) offer immense value for scientific and clinical investigations. The inability of supervised EEG encoders to learn robust EEG patterns and their…

Signal Processing · Electrical Eng. & Systems 2025-12-25 Gayal Kuruppu , Neeraj Wagh , Vaclav Kremen , Sandipan Pati , Gregory Worrell , Yogatheesan Varatharajah

Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by the progressive accumulation of misfolded proteins, leading to cognitive decline. This study presents a novel stochastic modelling approach to simulate the…

Neurons and Cognition · Quantitative Biology 2024-11-06 Alec MacIver , Hina Shaheen

Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder in children, characterized by difficulties in attention, hyperactivity, and impulsivity. Early and accurate diagnosis of ADHD is critical for effective…

Signal Processing · Electrical Eng. & Systems 2025-04-08 Md Bayazid Hossain , Md Anwarul Islam Himel , Md Abdur Rahim , Shabbir Mahmood , Abu Saleh Musa Miah , Jungpil Shin

The uncertainty of clinical examinations frequently leads to irregular observation intervals in longitudinal imaging data, posing challenges for modeling disease progression.Most existing imaging-based disease prediction models operate in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Xin Hong , Ying Shi , Yinhao Li , Yen-Wei Chen

Atrial Fibrillation (AF) is a common cardiac arrhythmia affecting a large number of people around the world. If left undetected, it will develop into chronic disability or even early mortality. However, patients who have this problem can…

Signal Processing · Electrical Eng. & Systems 2021-01-20 Dacheng Chen , Dan Li , Xiuqin Xu , Ruizhi Yang , See-Kiong Ng

Alzheimer's disease (AD) and sleep disorders exhibit a close association, where disruptions in sleep patterns often precede the onset of Mild Cognitive Impairment (MCI) and early-stage AD. This study delves into the potential of utilizing…

Alzheimer's disease (AD) is known as one of the major causes of dementia and is characterized by slow progression over several years, with no treatments or available medicines. In this regard, there have been efforts to identify the risk of…

Computer Vision and Pattern Recognition · Computer Science 2020-08-28 Wonsik Jung , Eunji Jun , Heung-Il Suk

Most brain disorders including Alzheimer's disease (AD) are related to alterations in the normal brain network organization and function. Exploring these network alterations using non-invasive and easy to use technique is a topic of great…

Neurons and Cognition · Quantitative Biology 2017-06-14 Aya Kabbara , Mahmoud Hassan , Mohamad Khalil , Wassim El Falou , Hassan Eid

Alzheimer's disease (AD) is the most common neurodegenerative disease in older people. Despite considerable efforts to find a cure for AD, there is a 99.6% failure rate of clinical trials for AD drugs, likely because AD patients cannot…

Machine Learning · Computer Science 2019-03-25 Jack Albright

Background: Mild cognitive impairment (MCI) is often considered a precursor to Alzheimer's disease (AD) due to the high rate of progression from MCI to AD. Sensitive neural biomarkers may provide a tool for an accurate MCI diagnosis,…

Neurons and Cognition · Quantitative Biology 2022-11-02 Adi Wijaya , Noor Akhmad Setiawan , Asma Hayati Ahmad , Rahimah Zakaria , Zahiruddin Othman

Foundation models (FMs) promise to extract unified representations that generalize across downstream tasks. They have emerged across fields, including electroencephalography (EEG), but it is less clear how effective they are in this…

Background: Dementia, particularly Alzheimer's Disease (AD), is a progressive neurodegenerative disorder marked by cognitive decline. Early detection, especially at the Mild Cognitive Impairment (MCI) stage, is essential for timely…

Signal Processing · Electrical Eng. & Systems 2025-10-16 Shivani Ranjan , Anant Jain , Robin Badal , Amit Kumar , Harshal Shende , Deepak Joshi , Pramod Yadav , Lalan Kumar

Robust strategies for Alzheimer's disease (AD) detection are important, given the high prevalence of AD. In this paper, we study the performance and generalizability of three approaches for AD detection from speech on the recent ADReSSo…

Computation and Language · Computer Science 2022-09-16 Aparna Balagopalan , Jekaterina Novikova

Bioelectric source analysis in the human brain from scalp electroencephalography (EEG) signals is sensitive to the conductivity of the different head tissues. Conductivity values are subject dependent, so non-invasive methods for…

Computational Engineering, Finance, and Science · Computer Science 2019-08-30 Kostiantyn Maksymenko , Maureen Clerc , Théodore Papadopoulo

As societies around the world are ageing, the number of Alzheimer's disease (AD) patients is rapidly increasing. To date, no low-cost, non-invasive biomarkers have been established to advance the objectivization of AD diagnosis and…

Parkinson's Disease PD is a progressive neurodegenerative disorder that affects motor and cognitive functions with early diagnosis being critical for effective clinical intervention Electroencephalography EEG offers a noninvasive and…

Automated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep learning methods. However, many of these…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Yifeng Wang , Ke Chen , Haohan Wang

Electroencephalography (EEG)-based auditory attention detection (AAD) offers a non-invasive way to enhance hearing aids, but conventional methods rely on too many electrodes, limiting wearability and comfort. This paper presents SHAP-AAD, a…

Signal Processing · Electrical Eng. & Systems 2025-07-08 Rayan Salmi , Guorui Lu , Qinyu Chen

Alzheimer's disease (AD) has become one of the most significant health challenges in an aging society. The use of spoken language-based AD detection methods has gained prevalence due to their scalability due to their scalability. Based on…

Computation and Language · Computer Science 2024-12-02 Junan Li , Yunxiang Li , Yuren Wang , Xixin Wu , Helen Meng
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