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We present the first acquisition-agnostic diffusion generative model for Magnetic Resonance Imaging (MRI) in the neonatal intensive care unit (NICU) to solve a range of inverse problems for shortening scan time and improving motion…

Medical Physics · Physics 2025-05-22 Yamin Arefeen , Brett Levac , Jonathan I. Tamir

Stroke poses an immense public health burden and remains among the primary causes of death and disability worldwide. Emergent therapy is often precluded by late or indeterminate times of onset before initial clinical presentation. Rapid,…

Medical Physics · Physics 2021-04-16 Leeor Alon , Seena Dehkharghani

DSC-MRI perfusion is a medical imaging technique for diagnosing and prognosing brain tumors and strokes. Its analysis relies on mathematical deconvolution, but noise or motion artifacts in a clinical environment can disrupt this process,…

Quantitative Methods · Quantitative Biology 2025-10-17 Pierre Fayolle , Alexandre Bône , Noëlie Debs , Mathieu Naudin , Pascal Bourdon , Remy Guillevin , David Helbert

Coronary stenosis is a major risk factor for ischemic heart events leading to increased mortality, and medical treatments for this condition require meticulous, labor-intensive analysis. Coronary angiography provides critical visual cues…

Image and Video Processing · Electrical Eng. & Systems 2025-08-04 Sumin Seo , In Kyu Lee , Hyun-Woo Kim , Jaesik Min , Chung-Hwan Jung

The diversity of cognitive deficits and neuropathological processes associated with dementias has encouraged divergence in pathophysiological explanations of disease. Here, we review an alternative framework that emphasises convergent…

Neurons and Cognition · Quantitative Biology 2020-06-12 Ece Kocagoncu , Anastasia Klimovich-Gray , Laura E Hughes , James B Rowe

Extracting stimulus features from neuronal ensembles is of great interest to the development of neuroprosthetics that project sensory information directly to the brain via electrical stimulation. Machine learning strategies that optimize…

Neurons and Cognition · Quantitative Biology 2020-09-08 Vivek Subramanian , Joshua Khani

Predicting the final ischaemic stroke lesion provides crucial information regarding the volume of salvageable hypoperfused tissue, which helps physicians in the difficult decision-making process of treatment planning and intervention.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Adriano Pinto , Sérgio Pereira , Raphael Meier , Roland Wiest , Victor Alves , Mauricio Reyes , Carlos A. Silva

Ischemic stroke occurs through a blockage of clogged blood vessels supplying blood to the brain. Segmentation of the stroke lesion is vital to improve diagnosis, outcome assessment and treatment planning. In this work, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Mobarakol Islam , N Rajiv Vaidyanathan , V Jeya Maria Jose , Hongliang Ren

In medical imaging, generative models are increasingly relied upon for two distinct but equally critical tasks: reconstruction, where the goal is to restore medical imaging (usually inverse problems like inpainting or superresolution), and…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Niklas Bubeck , Yundi Zhang , Suprosanna Shit , Daniel Rueckert , Jiazhen Pan

Stroke remains a leading cause of global morbidity and mortality, imposing a heavy socioeconomic burden. Advances in endovascular reperfusion therapy and CT and MR imaging for treatment guidance have significantly improved patient outcomes.…

We report a series of deep learning models to solve complex forward and inverse design problems in molecular modeling and design. Using both diffusion models inspired by nonequilibrium thermodynamics and attention-based transformer…

Materials Science · Physics 2023-06-21 Rachel K. Luu , Marcin Wysokowski , Markus J. Buehler

Intracranial Hemorrhage is a potentially lethal condition whose manifestation is vastly diverse and shifts across clinical centers worldwide. Deep-learning-based solutions are starting to model complex relations between brain structures,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Antoine P. Sanner , Jonathan Stieber , Nils F. Grauhan , Suam Kim , Marc A. Brockmann , Ahmed E. Othman , Anirban Mukhopadhyay

Cephalometric landmark detection is essential for orthodontic diagnostics and treatment planning. Nevertheless, the scarcity of samples in data collection and the extensive effort required for manual annotation have significantly impeded…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Dongqian Guo , Wencheng Han , Pang Lyu , Yuxi Zhou , Jianbing Shen

During the diagnosis of ischemic strokes, the Circle of Willis and its surrounding vessels are the arteries of interest. Their visualization in case of an acute stroke is often enabled by Computed Tomography Angiography (CTA). Still, the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Florian Thamm , Markus Jürgens , Oliver Taubmann , Aleksandra Thamm , Leonhard Rist , Hendrik Ditt , Andreas Maier

Acute intracerebral hemorrhage is a life-threatening condition that demands immediate medical intervention. Intraparenchymal hemorrhage (IPH) and intraventricular hemorrhage (IVH) are critical subtypes of this condition. Clinically, when…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Changwei Song , Qing Zhao , Jianqiang Li , Xin Yue , Ruoyun Gao , Zhaoxuan Wang , An Gao , Guanghui Fu

Ptychography is a well-established coherent diffraction imaging technique that enables non-invasive imaging of samples at a nanometer scale. It has been extensively used in various areas such as the defense industry or materials science.…

Computer Vision and Pattern Recognition · Computer Science 2022-05-24 Semih Barutcu , Doğa Gürsoy , Aggelos K. Katsaggelos

To shorten the door-to-puncture time for better treating patients with acute ischemic stroke, it is highly desired to obtain quantitative cerebral perfusion images using C-arm cone-beam computed tomography (CBCT) equipped in the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Haotian Zhao , Ruifeng Chen , Jing Yan , Juan Feng , Jun Xiang , Yang Chen , Dong Liang , Yinsheng Li

CT perfusion imaging (CTP) is used in the diagnostic workup of acute ischemic stroke (AIS). CTP may be performed within the angio suite using flat detector CT (FDCT) to help reduce patient management time. In order to significantly improve…

Medical Physics · Physics 2022-04-21 Vojtěch Kulvait , Philip Hoelter , Robert Frysch , Hana Haseljić , Arnd Doerfler , Georg Rose

Divergent brain connectivity is thought to underlie the behavioral and cognitive symptoms observed in many neurodevelopmental disorders. Quantifying divergence from neurotypical connectivity patterns offers a promising pathway to inform…

Neurons and Cognition · Quantitative Biology 2024-11-19 Rui Sherry Shen , Yusuf Osmanlıoğlu , Drew Parker , Darien Aunapu , Benjamin E. Yerys , Birkan Tunç , Ragini Verma

Diffusion models have established themselves as state-of-the-art generative models across various data modalities, including images and videos, due to their ability to accurately approximate complex data distributions. Unlike traditional…

Machine Learning · Computer Science 2025-10-23 Daniel Wesego