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Perfusion imaging plays a crucial role in acute stroke diagnosis and treatment decision making. Current perfusion analysis relies on deconvolution of the measured signals, an operation that is mathematically ill-conditioned and requires…

Computer Vision and Pattern Recognition · Computer Science 2018-10-12 David Robben , Paul Suetens

Although deep learning techniques show promising results for many neuroimaging tasks in research settings, they have not yet found widespread use in clinical scenarios. One of the reasons for this problem is that many machine learning…

Image and Video Processing · Electrical Eng. & Systems 2024-12-05 Vibujithan Vigneshwaran , Erik Ohara , Matthias Wilms , Nils Forkert

Diffusion Generative Models (DGM) have rapidly surfaced as emerging topics in the field of computer vision, garnering significant interest across a wide array of deep learning applications. Despite their high computational demand, these…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Denisha Thakkar , Vincent Quoc-Huy Trinh , Sonal Varma , Samira Ebrahimi Kahou , Hassan Rivaz , Mahdi S. Hosseini

Mechanical thrombectomy has become the standard of care in patients with stroke due to large vessel occlusion (LVO). However, only 50% of successfully treated patients show a favorable outcome. We developed and evaluated interpretable deep…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Lisa Herzog , Pascal Bühler , Ezequiel de la Rosa , Beate Sick , Susanne Wegener

A stroke occurs when an artery in the brain ruptures and bleeds or when the blood supply to the brain is cut off. Blood and oxygen cannot reach the brain's tissues due to the rupture or obstruction resulting in tissue death. The Middle…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Ujjwal Upadhyay , Mukul Ranjan , Satish Golla , Swetha Tanamala , Preetham Sreenivas , Sasank Chilamkurthy , Jeyaraj Pandian , Jason Tarpley

We investigate the approximation efficiency of score functions by deep neural networks in diffusion-based generative modeling. While existing approximation theories utilize the smoothness of score functions, they suffer from the curse of…

Machine Learning · Computer Science 2023-09-21 Song Mei , Yuchen Wu

Computational models of vision have traditionally been developed in a bottom-up fashion, by hierarchically composing a series of straightforward operations - i.e. convolution and pooling - with the aim of emulating simple and complex cells…

Computer Vision and Pattern Recognition · Computer Science 2022-03-23 Simone Azeglio , Simone Poetto , Luca Savant Aira , Marco Nurisso

At present, the majority of the proposed Deep Learning (DL) methods provide point predictions without quantifying the models uncertainty. However, a quantification of the reliability of automated image analysis is essential, in particular…

Image and Video Processing · Electrical Eng. & Systems 2020-08-17 Lisa Herzog , Elvis Murina , Oliver Dürr , Susanne Wegener , Beate Sick

In this paper, we study the problem of using representation learning to assist information diffusion prediction on graphs. In particular, we aim at estimating the probability of an inactive node to be activated next in a cascade. Despite…

Machine Learning · Computer Science 2017-12-01 Jia Wang , Vincent W. Zheng , Zemin Liu , Kevin Chen-Chuan Chang

The dose of X-ray radiation and the scanning time are crucial factors in computed tomography (CT) for clinical applications. In this work, we introduce a multi-source static CT imaging system designed to rapidly acquire sparse view and…

Medical Physics · Physics 2025-01-03 Ziju Shen , Haimiao Zhang , Bin Dong , Jun Qiu , Yunxiang Li , Zhili Cui

Accurate segmentation of ischemic stroke lesions from diffusion magnetic resonance imaging (MRI) is essential for clinical decision-making and outcome assessment. Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC)…

Image and Video Processing · Electrical Eng. & Systems 2025-12-24 Muhammad Usman , Azka Rehman , Muhammad Mutti Ur Rehman , Abd Ur Rehman , Muhammad Umar Farooq

Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Nivetha Jayakumar , Swakshar Deb , Bahram Jafrasteh , Qingyu Zhao , Miaomiao Zhang

Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…

Machine Learning · Computer Science 2026-01-30 Yiying Sheng , Wenhao Ding , Dylan Roi , Leonard Leong Litt Yeo , Hwa Liang Leo , Choon Hwai Yap

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships.…

Machine Learning · Computer Science 2025-07-08 Haoran Zhang , Mingyuan Zhou , Wesley Tansey

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

In this paper, an automatic algorithm aimed at volumetric segmentation of acute ischemic stroke lesion in non-contrast computed tomography brain 3D images is proposed. Our deep-learning approach is based on the popular 3D U-Net…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 A. V. Dobshik , S. K. Verbitskiy , I. A. Pestunov , K. M. Sherman , Yu. N. Sinyavskiy , A. A. Tulupov , V. B. Berikov

The quantification of myocardial perfusion MRI has the potential to provide a fast, automated and user-independent assessment of myocardial ischaemia. However, due to the relatively high noise level and low temporal resolution of the…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Cian M. Scannell , Piet van den Bosch , Amedeo Chiribiri , Jack Lee , Marcel Breeuwer , Mitko Veta

The patient with ischemic stroke can benefit most from the earliest possible definitive diagnosis. While the high quality medical resources are quite scarce across the globe, an automated diagnostic tool is expected in analyzing the…

Computer Vision and Pattern Recognition · Computer Science 2018-03-16 Zhiyang Liu , Chen Cao , Shuxue Ding , Tong Han , Hong Wu , Sheng Liu

Purpose: Magnetic Resonance Imaging (MRI) enables non-invasive assessment of brain abnormalities during early life development. Permanent magnet scanners operating in the neonatal intensive care unit (NICU) facilitate MRI of sick infants,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-23 Yamin Arefeen , Brett Levac , Bhairav Patel , Chang Ho , Jonathan I. Tamir

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…