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Early fault diagnosis in complex mechanical systems such as gearbox has always been a great challenge, even with the recent development in deep neural networks. The performance of a classic fault diagnosis system predominantly depends on…
Applying deep learning concepts from image detection and graph theory has greatly advanced protein-ligand binding affinity prediction, a challenge with enormous ramifications for both drug discovery and protein engineering. We build upon…
Accurate prediction of drug molecule solubility is crucial for therapeutic effectiveness and safety. Traditional methods often miss complex molecular structures, leading to inaccuracies. We introduce the YZS-Model, a deep learning framework…
The protein-ligand binding affinity (PLA) prediction goal is to predict whether or not the ligand could bind to a protein sequence. Recently, in PLA prediction, deep learning has received much attention. Two steps are involved in deep…
Recent successes in image analysis with deep neural networks are achieved almost exclusively with Convolutional Neural Networks (CNNs), typically trained using the backpropagation (BP) algorithm. In a 2022 preprint, Geoffrey Hinton proposed…
Deep convolutional neural networks have proven their effectiveness, and have been acknowledged as the most dominant method for image classification. However, a severe drawback of deep convolutional neural networks is poor explainability.…
Molecular phenotyping by gene expression profiling is common in contemporary cancer research and in molecular diagnostics. However, molecular profiling remains costly and resource intense to implement, and is just starting to be introduced…
Background: Spatial transcriptomics have emerged as a powerful tool in biomedical research because of its ability to capture both the spatial contexts and abundance of the complete RNA transcript profile in organs of interest. However,…
Learning representations that accurately capture long-range dependencies in sequential inputs -- including text, audio, and genomic data -- is a key problem in deep learning. Feed-forward convolutional models capture only feature…
With the upcoming commensal surveys for Fast Radio Bursts (FRBs), and their high candidate rate, usage of machine learning algorithms for candidate classification is a necessity. Such algorithms will also play a pivotal role in sending…
A deep feature based saliency model (DeepFeat) is developed to leverage the understanding of the prediction of human fixations. Traditional saliency models often predict the human visual attention relying on few level image cues. Although…
Long-term time series forecasting is a vital task and has a wide range of real applications. Recent methods focus on capturing the underlying patterns from one single domain (e.g. the time domain or the frequency domain), and have not taken…
This work leverages the recent advancements of deep learning in image processing to find optimal locations that present the important characteristics of a field. The data for training are collected at different fields in local farms with…
Deep learning generally suffers from enormous computational resources and time-consuming training processes. Broad Learning System (BLS) and its convolutional variants have been proposed to mitigate these issues and have achieved superb…
Effective feature interaction modeling is critical for enhancing the accuracy of click-through rate (CTR) prediction in industrial recommender systems. Most of the current deep CTR models resort to building complex network architectures to…
Visual saliency prediction using transformers - Convolutional neural networks (CNNs) have significantly advanced computational modelling for saliency prediction. However, accurately simulating the mechanisms of visual attention in the human…
Fingerprint recognition has been utilized for cellphone authentication, airport security and beyond. Many different features and algorithms have been proposed to improve fingerprint recognition. In this paper, we propose an end-to-end deep…
Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…
Understanding non-genetic determinants of cell fate is critical for developing and improving cancer therapies, as genetically identical cells can exhibit divergent outcomes under the same treatment conditions. In this work, we present a…
Thanks to rapidly evolving sequencing techniques, the amount of genomic data at our disposal is growing increasingly large. Determining the gene structure is a fundamental requirement to effectively interpret gene function and regulation.…