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Molecular representation learning is pivotal for various molecular property prediction tasks related to drug discovery. Robust and accurate benchmarks are essential for refining and validating current methods. Existing molecular property…

Chemical Physics · Physics 2024-06-27 Shikun Feng , Jiaxin Zheng , Yinjun Jia , Yanwen Huang , Fengfeng Zhou , Wei-Ying Ma , Yanyan Lan

Feature distillation is an effective way to improve the performance for a smaller student model, which has fewer parameters and lower computation cost compared to the larger teacher model. Unfortunately, there is a common obstacle - the gap…

Computer Vision and Pattern Recognition · Computer Science 2020-10-14 Kaiyu Yue , Jiangfan Deng , Feng Zhou

Machine learning (ML) is revolutionising drug discovery by expediting the prediction of small molecule properties essential for developing new drugs. These properties -- including absorption, distribution, metabolism and excretion (ADME)--…

Machine Learning · Computer Science 2024-08-02 Alex G. C. de Sá , David B. Ascher

Out-of-distribution (OOD) detection identifies test samples that differ from the training data, which is critical to ensuring the safety and reliability of machine learning (ML) systems. While a plethora of methods have been developed to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Viet Duong , Qiong Wu , Zhengyi Zhou , Eric Zavesky , Jiahe Chen , Xiangzhou Liu , Wen-Ling Hsu , Huajie Shao

Molecular property prediction integrates quantum chemistry, cheminformatics, and deep learning to connect molecular structure with physicochemical and biological behavior. This survey traces four complementary paradigms, including Quantum,…

Emotion recognition is involved in several real-world applications. With an increase in available modalities, automatic understanding of emotions is being performed more accurately. The success in Multimodal Emotion Recognition (MER),…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 Riccardo Franceschini , Enrico Fini , Cigdem Beyan , Alessandro Conti , Federica Arrigoni , Elisa Ricci

Designing safe and sustainable chemicals is critical to combat chemical pollution in our environment. Machine learning (ML) methods have been developed to aid with de novo molecule design. However, data on the environmental impacts of…

Human-Computer Interaction · Computer Science 2026-05-18 Coelina Robinson , Franziska Weissbach , Kjell Jorner , Mennatallah El-Assady , Christina Humer

A molecule is a complex of heterogeneous components, and the spatial arrangements of these components determine the whole molecular properties and characteristics. With the advent of deep learning in computational chemistry, several studies…

Machine Learning · Computer Science 2021-06-15 Jeonghee Jo , Bumju Kwak , Byunghan Lee , Sungroh Yoon

Our experience of the world is multimodal - we see objects, hear sounds, feel texture, smell odors, and taste flavors. Modality refers to the way in which something happens or is experienced and a research problem is characterized as…

Machine Learning · Computer Science 2017-08-02 Tadas Baltrušaitis , Chaitanya Ahuja , Louis-Philippe Morency

Neural networks trained on real-world datasets with long-tailed label distributions are biased towards frequent classes and perform poorly on infrequent classes. The imbalance in the ratio of positive and negative samples for each class…

Computer Vision and Pattern Recognition · Computer Science 2021-05-25 Kevin Duarte , Yogesh S. Rawat , Mubarak Shah

Arbitrary-oriented object detection is a relatively emerging but challenging task. Although remarkable progress has been made, there still remain many unsolved issues due to the large diversity of patterns in orientation, scale, aspect…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Peng Sun , Yongbin Zheng , Wenqi Wu , Wanying Xu , Shengjian Bai

This paper explores a new natural language processing task, review-driven multi-label music style classification. This task requires the system to identify multiple styles of music based on its reviews on websites. The biggest challenge…

Computation and Language · Computer Science 2018-08-24 Guangxiang Zhao , Jingjing Xu , Qi Zeng , Xuancheng Ren

Learning with noisy labels has gained increasing attention because the inevitable imperfect labels in real-world scenarios can substantially hurt the deep model performance. Recent studies tend to regard low-loss samples as clean ones and…

Machine Learning · Computer Science 2024-02-20 Huafeng Liu , Mengmeng Sheng , Zeren Sun , Yazhou Yao , Xian-Sheng Hua , Heng-Tao Shen

Accurate prediction of molecular properties is crucial in drug discovery. Traditional methods often overlook that real-world molecules typically exhibit multiple property labels with complex correlations. To this end, we propose a novel…

Quantitative Methods · Quantitative Biology 2024-08-13 Linjia Kang , Songhua Zhou , Shuyan Fang , Shichao Liu

To perform recognition, molecules must locate and specifically bind their targets within a noisy biochemical environment with many look-alikes. Molecular recognition processes, especially the induced-fit mechanism, are known to involve…

Biomolecules · Quantitative Biology 2010-07-27 Yonatan Savir , Tsvi Tlusty

In multi-label classification, an instance may be associated with a set of labels simultaneously. Recently, the research on multi-label classification has largely shifted its focus to the other end of the spectrum where the number of labels…

Machine Learning · Computer Science 2016-04-06 Li Li , Houfeng Wang

This thesis is designed to be a self-contained exposition of the neurobiological and mathematical aspects of sensory perception, memory, and learning with a bias towards olfaction. The final chapters introduce a new approach to modeling…

Neurons and Cognition · Quantitative Biology 2020-09-07 Jack A. Cook

Recent methods for deep metric learning have been focusing on designing different contrastive loss functions between positive and negative pairs of samples so that the learned feature embedding is able to pull positive samples of the same…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Shichao Kan , Zhiquan He , Yigang Cen , Yang Li , Vladimir Mladenovic , Zhihai He

Two-class classification problems are often characterized by an imbalance between the number of majority and minority datapoints resulting in poor classification of the minority class in particular. Traditional approaches, such as…

Machine Learning · Computer Science 2025-07-11 Karen Medlin , Sven Leyffer , Krishnan Raghavan

Mass spectrometry is a widely used method to study molecules and processes in medicine, life sciences, chemistry, catalysis, and industrial product quality control, among many other applications. One of the main features of some mass…

Chemical Physics · Physics 2024-07-02 Daniil A. Boiko , Valentine P. Ananikov
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