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Large-language models (LLMs) are rapidly being applied to radiology, enabling automated image interpretation and report generation tasks. Their deployment in clinical practice requires both high diagnostic accuracy and low inference…

Tissues and Organs · Quantitative Biology 2025-11-11 Jyun-Ping Kao

As Large Language Models (LLMs) gain traction, their reliance on power-hungry GPUs places ever-increasing energy demands, raising environmental and monetary concerns. Inference dominates LLM workloads, presenting a critical challenge for…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-04 Andreas Kosmas Kakolyris , Dimosthenis Masouros , Petros Vavaroutsos , Sotirios Xydis , Dimitrios Soudris

Large Language Models (LLMs) are becoming the backbone of modern cloud services, yet their inference costs are dominated by GPU energy. Unlike traditional GPU workloads, LLM inference has two stages with different characteristics: the…

Performance · Computer Science 2025-08-25 Qunyou Liu , Darong Huang , Marina Zapater , David Atienza

The autoregressive nature of conventional large language models (LLMs) inherently limits inference speed, as tokens are generated sequentially. While speculative and parallel decoding techniques attempt to mitigate this, they face…

Artificial Intelligence · Computer Science 2024-10-22 Aishwarya P S , Pranav Ajit Nair , Yashas Samaga , Toby Boyd , Sanjiv Kumar , Prateek Jain , Praneeth Netrapalli

Deploying Large Language Models (LLMs) on edge devices presents significant challenges due to computational constraints, memory limitations, inference speed, and energy consumption. Model quantization has emerged as a key technique to…

The rapid expansion of Large Language Models (LLMs) has introduced unprecedented energy demands, extending beyond training to large-scale inference workloads that often dominate total lifecycle consumption. Deploying these models requires…

Artificial Intelligence · Computer Science 2025-11-11 Francisco Caravaca , Ángel Cuevas , Rubén Cuevas

Large language model (LLM) inference has been a prevalent demand in daily life and industries. The large tensor sizes and computing complexities in LLMs have brought challenges to memory, computing, and databus. This paper proposes a…

Hardware Architecture · Computer Science 2025-09-19 Yimin Wang , Yue Jiet Chong , Xuanyao Fong

Large language models (LLMs) have demonstrated remarkable performance across a wide range of language processing tasks. However, this success comes at the cost of substantial computation and memory requirements, which significantly impedes…

Machine Learning · Computer Science 2026-01-21 Fen-Yu Hsieh , Yun-Chang Teng , Ding-Yong Hong , Jan-Jan Wu

Large language models (LLMs) are increasingly deployed on customer devices. To support them, current devices are adopting SoCs (System on Chip) with NPUs (Neural Processing Unit) installed. Although high performance is expected, LLM…

Hardware Architecture · Computer Science 2025-11-17 Jianyu Wei , Qingtao Li , Shijie Cao , Lingxiao Ma , Zixu Hao , Yanyong Zhang , Xiaoyan Hu , Ting Cao

Graphics Processing Units (GPUs) have become the leading hardware accelerator for deep learning applications and are used widely in training and inference of transformers; transformers have achieved state-of-the-art performance in many…

Hardware Architecture · Computer Science 2024-05-03 Andy He , Darren Key , Mason Bulling , Andrew Chang , Skyler Shapiro , Everett Lee

We present a cross-architecture evaluation of production LLM inference on AMD Instinct MI325X GPUs, benchmarking four models spanning 235B to 1 trillion parameters across three architectural families (MoE+MLA, Dense+GQA, MoE+GQA) on an…

Hardware Architecture · Computer Science 2026-03-12 Athos Georgiou

Nowadays, many companies possess various types of AI accelerators, forming heterogeneous clusters. Efficiently leveraging these clusters for high-throughput large language model (LLM) inference services can significantly reduce costs and…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-23 Yi Xiong , Jinqi Huang , Wenjie Huang , Xuebing Yu , Entong Li , Zhixiong Ning , Jinhua Zhou , Li Zeng , Xin Chen

Compared to traditional machine learning models, recent large language models (LLMs) can exhibit multi-task-solving capabilities through multiple dialogues and multi-modal data sources. These unique characteristics of LLMs, together with…

Machine Learning · Computer Science 2026-01-01 Liangqi Yuan , Dong-Jun Han , Shiqiang Wang , Christopher G. Brinton

Large language models (LLMs) have shown remarkable performance across a wide range of applications, often outperforming human experts. However, deploying these gigantic models efficiently for diverse inference use cases requires carefully…

Recent breakthroughs in Large-scale language models (LLMs) have demonstrated impressive performance on various tasks. The immense sizes of LLMs have led to very high resource demand and cost for running the models. Though the models are…

Machine Learning · Computer Science 2024-03-05 Juntao Zhao , Borui Wan , Yanghua Peng , Haibin Lin , Chuan Wu

Transformer-based Large Language Models (LLMs) have made a significant impact on various domains. However, LLMs' efficiency suffers from both heavy computation and memory overheads. Compression techniques like sparsification and…

The rapid advancement of Large Language Models (LLMs) necessitates a deep understanding of their fundamental performance limits. This paper investigates the limits of LLM inference, focusing on hardware-imposed bottlenecks in…

Hardware Architecture · Computer Science 2025-11-17 Michael Davies , Neal Crago , Karthikeyan Sankaralingam , Christos Kozyrakis

The rapid scaling of large language models (LLMs) has unveiled critical limitations in current hardware architectures, including constraints in memory capacity, computational efficiency, and interconnection bandwidth. DeepSeek-V3, trained…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-24 Chenggang Zhao , Chengqi Deng , Chong Ruan , Damai Dai , Huazuo Gao , Jiashi Li , Liyue Zhang , Panpan Huang , Shangyan Zhou , Shirong Ma , Wenfeng Liang , Ying He , Yuqing Wang , Yuxuan Liu , Y. X. Wei

Energy is now a critical ML computing resource. While measuring energy consumption and observing trends is a valuable first step, accurately understanding and diagnosing why those differences occur is crucial for optimization. To that end,…

Machine Learning · Computer Science 2026-02-02 Jae-Won Chung , Ruofan Wu , Jeff J. Ma , Mosharaf Chowdhury

Large language models (LLMs) have revolutionized AI applications, yet their enormous computational demands severely limit deployment and real-time performance. Quantization methods can help reduce computational costs, however, attaining the…

Machine Learning · Computer Science 2025-09-03 Shaobo Ma , Chao Fang , Haikuo Shao , Zhongfeng Wang