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Purpose: Large Language Models (LLMs) hold significant promise for medical applications. Retrieval Augmented Generation (RAG) emerges as a promising approach for customizing domain knowledge in LLMs. This case study presents the development…

Retrieval Augmented Generation (RAG) is a technique used to augment Large Language Models (LLMs) with contextually relevant, time-critical, or domain-specific information without altering the underlying model parameters. However,…

Information Retrieval · Computer Science 2024-08-20 Laurent Mombaerts , Terry Ding , Adi Banerjee , Florian Felice , Jonathan Taws , Tarik Borogovac

Retrieval-Augmented Generation (RAG) enables large language models (LLMs) to access broader knowledge sources, yet factual inconsistencies persist due to noise in retrieved documents-even with advanced retrieval methods. We demonstrate that…

Computation and Language · Computer Science 2025-06-04 Yongjian Li , HaoCheng Chu , Yukun Yan , Zhenghao Liu , Shi Yu , Zheni Zeng , Ruobing Wang , Sen Song , Zhiyuan Liu , Maosong Sun

Considering the inherent limitations of parametric knowledge in large language models (LLMs), retrieval-augmented generation (RAG) is widely employed to expand their knowledge scope. Since RAG has shown promise in knowledge-intensive tasks…

Computation and Language · Computer Science 2025-05-20 Yuhao Wang , Ruiyang Ren , Yucheng Wang , Wayne Xin Zhao , Jing Liu , Hua Wu , Haifeng Wang

Chemical synthesis, as a foundational methodology in the creation of transformative molecules, exerts substantial influence across diverse sectors from life sciences to materials and energy. Current chemical synthesis practices emphasize…

Retrieval-Augmented Generation (RAG) mitigates hallucination in Large Language Models (LLMs) by incorporating external data, with Knowledge Graphs (KGs) offering crucial information for question answering. Traditional Knowledge Graph…

Computation and Language · Computer Science 2025-09-08 Yushi Sun , Kai Sun , Yifan Ethan Xu , Xiao Yang , Xin Luna Dong , Nan Tang , Lei Chen

Electronic design engineers often struggle to efficiently access relevant information for tasks like design verification and technology development. While large language models (LLMs) can enhance productivity as conversational agents,…

Computation and Language · Computer Science 2025-06-10 Luyao Shi , Michael Kazda , Charles Schmitter , Hemlata Gupta

Large Language Models are now key assistants in human decision-making processes. However, a common note always seems to follow: "LLMs can make mistakes. Be careful with important info." This points to the reality that not all outputs from…

Computation and Language · Computer Science 2025-05-16 Longchao Da , Parth Mitesh Shah , Kuan-Ru Liou , Jiaxing Zhang , Hua Wei

Recent developments in large language models (LLMs) have led to significant improvements in intelligent dialogue systems'ability to handle complex inquiries. However, current LLMs still exhibit limitations in specialized domain knowledge,…

Computation and Language · Computer Science 2024-09-23 Shuting Yang , Zehui Liu , Wolfgang Mayer

Large Language Models (LLMs) are adept at generating responses based on information within their context. While this ability is useful for interacting with structured data like code files, another popular method, Retrieval-Augmented…

Computation and Language · Computer Science 2025-10-22 Mihir Gupte , Paolo Giusto , Ramesh S

This research pioneers the use of fine-tuned Large Language Models (LLMs) to automate Systematic Literature Reviews (SLRs), presenting a significant and novel contribution in integrating AI to enhance academic research methodologies. Our…

Computation and Language · Computer Science 2025-02-21 Teo Susnjak , Peter Hwang , Napoleon H. Reyes , Andre L. C. Barczak , Timothy R. McIntosh , Surangika Ranathunga

Retrieval Augmented Generation (RAG) provides the necessary informational grounding to LLMs in the form of chunks retrieved from a vector database or through web search. RAG could also use knowledge graph triples as a means of providing…

Information Retrieval · Computer Science 2026-03-31 Shalin Shah , Srikanth Ryali , Ramasubbu Venkatesh

Large Language Model (LLM) has demonstrated significant success in a range of natural language processing (NLP) tasks within general domain. The emergence of LLM has introduced innovative methodologies across diverse fields, including the…

Information Retrieval · Computer Science 2025-07-30 Jiheng Liang , Zujie Xie , Ziru Yu , Xiangyang Yu

Large Language Models (LLMs) have recently demonstrated remarkable reasoning abilities, yet hallucinate on knowledge-intensive tasks. Retrieval-augmented generation (RAG) mitigates this issue by grounding answers in external sources, e.g.,…

Computation and Language · Computer Science 2026-01-29 Kaehyun Um , KyuHwan Yeom , Haerim Yang , Minyoung Choi , Hyeongjun Yang , Kyong-Ho Lee

Large Language Models (LLMs) have significantly advanced medical question-answering by leveraging extensive clinical data and medical literature. However, the rapid evolution of medical knowledge and the labor-intensive process of manually…

Computation and Language · Computer Science 2025-07-01 Mohammad Reza Rezaei , Reza Saadati Fard , Jayson L. Parker , Rahul G. Krishnan , Milad Lankarany

Fine-tuning is an immensely resource-intensive process when retraining Large Language Models (LLMs) to incorporate a larger body of knowledge. Although many fine-tuning techniques have been developed to reduce the time and computational…

Computation and Language · Computer Science 2025-08-01 Hruday Markondapatnaikuni , Basem Suleiman , Abdelkarim Erradi , Shijing Chen

Large language models (LLMs) often struggle with knowledge-intensive tasks due to hallucinations and outdated parametric knowledge. While Retrieval-Augmented Generation (RAG) addresses this by integrating external corpora, its effectiveness…

Computation and Language · Computer Science 2026-02-04 Su Dong , Qinggang Zhang , Yilin Xiao , Shengyuan Chen , Chuang Zhou , Xiao Huang

Large language models are a form of artificial intelligence systems whose primary knowledge consists of the statistical patterns, semantic relationships, and syntactical structures of language1. Despite their limited forms of "knowledge",…

Artificial Intelligence · Computer Science 2023-10-13 Yizhen Zheng , Huan Yee Koh , Jiaxin Ju , Anh T. N. Nguyen , Lauren T. May , Geoffrey I. Webb , Shirui Pan

Large language models (LLMs) struggle with relation completion (RC), both with and without retrieval-augmented generation (RAG), particularly when the required information is rare or sparsely represented. To address this, we propose a novel…

Computation and Language · Computer Science 2026-04-27 Fahmida Alam , Mihai Surdeanu , Ellen Riloff

This paper explores the use of large language models (LLMs) to assist in the development of new disease modules for Synthea, an open-source synthetic health data generator. Incorporating LLMs into the module development process has the…

Artificial Intelligence · Computer Science 2025-07-30 Mark A. Kramer , Aanchal Mathur , Caroline E. Adams , Jason A. Walonoski