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Quantum machine learning (QML) has great potential for the analysis of chemical datasets. However, conventional quantum data-encoding schemes, such as fingerprint encoding, are generally unfeasible for the accurate representation of…

Quantum Physics · Physics 2025-11-18 Choy Boy , Edoardo Altamura , Dilhan Manawadu , Ivano Tavernelli , Stefano Mensa , David J. Wales

Quantum machine learning algorithms, the extensions of machine learning to quantum regimes, are believed to be more powerful as they leverage the power of quantum properties. Quantum machine learning methods have been employed to solve…

Computational Physics · Physics 2021-06-01 Shree Hari Sureshbabu , Manas Sajjan , Sangchul Oh , Sabre Kais

Quantum computing opens up new possibilities for the simulation of many-body nuclear systems. As the number of particles in a many-body system increases, the size of the space if the associated Hamiltonian increases exponentially. This…

Quantum Physics · Physics 2022-09-19 Isaac Hobday , Paul Stevenson , James Benstead

This paper presents a new method to reduce the optimization of a pseudo-Boolean function to QUBO problem which can be solved by quantum annealer. The new method has two aspects, one is coefficient optimization and the other is variable…

Cryptography and Security · Computer Science 2022-11-21 Anpeng Zhang , Xiutao Feng

We present a framework that formulates the quest for the most efficient quantum state tomography scheme as an optimization problem which can be solved numerically. This approach can be applied to a broad spectrum of relevant setups…

Quantum Physics · Physics 2021-12-17 Violeta N. Ivanova-Rohling , Guido Burkard , Niklas Rohling

A new concept of the molecular structure optimization method based on quantum dynamics computations is presented. Nuclei are treated as quantum mechanical particles, as are electrons, and the many-body wave function of the system is…

We construct quantum error-correcting codes that embed a finite-dimensional code space in the infinite-dimensional Hilbert state space of rotational states of a rigid body. These codes, which protect against both drift in the body's…

Quantum Physics · Physics 2020-09-09 Victor V. Albert , Jacob P. Covey , John Preskill

Quantum computing has gained a lot of attention recently, and scientists have seen potential applications in this field using quantum computing for Cryptography and Communication to Machine Learning and Healthcare. Protein folding has been…

Quantum Physics · Physics 2022-11-16 Hasan Mustafa , Sai Nandan Morapakula , Prateek Jain , Srinjoy Ganguly

The ability of quantum computers to overcome the exponential memory scaling of many-body problems is expected to transform quantum chemistry. Quantum algorithms require accurate representations of electronic states on a quantum device, but…

Chemical Physics · Physics 2024-04-26 Hugh G. A. Burton

Quantum chemistry has been viewed as one of the potential early applications of quantum computing. Two techniques have been proposed for electronic structure calculations: (i) the variational quantum eigensolver and (ii) the…

Quantum Physics · Physics 2021-04-19 Christina Daniel , Diksha Dhawan , Dominika Zgid , James K. Freericks

The accurate treatment of electron correlation in extended molecular systems remains computationally challenging using classical electronic structure methods. Hybrid quantum-classical algorithms offer a potential route to overcome these…

With the advent of novel quantum computing technologies, and the knowledge that such technology might be used to fundamentally change computing applications, a prime opportunity has presented itself to investigate the practical application…

Computational Engineering, Finance, and Science · Computer Science 2024-02-13 Kevin Wils , Boyang Chen

Quantum computers are reaching one crucial milestone after another. Motivated by their progress in quantum chemistry, we have performed an extensive series of simulations of quantum-computer runs that were aimed at inspecting best-practice…

Quantum Physics · Physics 2022-01-27 Ivana Miháliková , Martin Friák , Matej Pivoluska , Martin Plesch , Martin Saip , Mojmír Šob

Variational quantum algorithms provide a direct, physics-based approach to protein structure prediction, but their accuracy is limited by the coarse resolution of the energy landscapes generated on current noisy devices. We propose a hybrid…

Emerging Technologies · Computer Science 2025-10-09 Yuqi Zhang , Yuxin Yang , Feixiong Chen , Cheng-Chang Lu , Nima Saeidi , Samuel L. Volchenboum , Junhan Zhao , Siwei Chen , Weiwen Jiang , Qiang Guan

Accurately and efficiently predicting the equilibrium geometries of large molecules remains a central challenge in quantum computational chemistry, even with hybrid quantum-classical algorithms. Two major obstacles hinder progress: the…

Quantum Physics · Physics 2026-04-07 Yajie Hao , Qiming Ding , Xiaoting Wang , Xiao Yuan

Quantum computing is emerging as a promising tool in nuclear physics. However, the cost of encoding fermionic operators hampers the application of algorithms in current noisy quantum devices. In this work, we analyze an encoding scheme…

Quantum computing is greatly advanced in recent years and is expected to transform the computation paradigm in the near future. Quantum circuit simulation plays a key role in the toolchain for the development of quantum hardware and…

Emerging Technologies · Computer Science 2020-07-21 Yuan-Hung Tsai , Jie-Hong R. Jiang , Chiao-Shan Jhang

There exist numerous problems in nature inherently described by finite $D$-dimensional states. Formulating these problems for execution on qubit-based quantum hardware requires mapping the qudit Hilbert space to that of multiqubit which may…

Quantum Physics · Physics 2026-02-23 Shakib Daryanoosh

In this work we investigate methods to improve the efficiency and scalability of quantum algorithms for quantum chemistry applications. We propose a transformation of the electronic structure Hamiltonian in the second quantization framework…

Stochastic Unit Commitment (SUC) has been proposed to manage the uncertainties driven by renewable integration, but it leads to significant computational complexity. When accelerated by Benders Decomposition (BD), the master problem becomes…

Quantum Physics · Physics 2026-02-25 Wei Hong , Wangkun Xu , Fei Teng