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Factors models are routinely used to analyze high-dimensional data in both single-study and multi-study settings. Bayesian inference for such models relies on Markov Chain Monte Carlo (MCMC) methods which scale poorly as the number of…

Methodology · Statistics 2025-04-29 Blake Hansen , Alejandra Avalos-Pacheco , Massimiliano Russo , Roberta De Vito

Deep generative models like VAEs and diffusion models have advanced various generation tasks by leveraging latent variables to learn data distributions and generate high-quality samples. Despite the field of explainable AI making strides in…

Machine Learning · Computer Science 2025-12-22 Mengdan Zhu , Raasikh Kanjiani , Jiahui Lu , Andrew Choi , Qirui Ye , Liang Zhao

In most of the world, causes of death are not recorded. Verbal autopsies are structured interviews with people close to the deceased, which are used to estimate the likelihood of various causes of death. Such estimates typically make use of…

Methodology · Statistics 2025-10-14 Nathan Higgins , James Liley , Eilidh Cowan

Understanding how generative models represent and transform data is a foundational problem in deep learning interpretability. While mechanistic interpretability of discriminative architectures has yielded substantial insights, relatively…

Machine Learning · Computer Science 2026-04-07 Dip Roy , Rajiv Misra , Sanjay Kumar Singh , Anisha Roy

In this paper we present a fully Bayesian latent variable model which exploits conditional nonlinear(in)-dependence structures to learn an efficient latent representation. The latent space is factorized to represent shared and private…

Machine Learning · Computer Science 2012-06-22 Andreas Damianou , Carl Ek , Michalis Titsias , Neil Lawrence

Recurrent binary outcomes within individuals, such as hospital readmissions, often reflect latent risk processes that evolve over time. Conventional methods like generalized linear mixed models and generalized estimating equations estimate…

Methodology · Statistics 2026-02-24 Niloofar Ramezani , Lori P. Selby , Pascal Nitiema , Jeffrey R. Wilson

Lesion-symptom mapping studies provide insight into what areas of the brain are involved in different aspects of cognition. This is commonly done via behavioral testing in patients with a naturally occurring brain injury or lesions (e.g.,…

Recent advances in deep learning have shown their ability to learn strong feature representations for images. The task of image clustering naturally requires good feature representations to capture the distribution of the data and…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Vignesh Prasad , Dipanjan Das , Brojeshwar Bhowmick

Modern epidemiological analytics increasingly use machine learning models that offer strong prediction but often lack calibrated uncertainty. Bayesian methods provide principled uncertainty quantification, yet are viewed as difficult to…

Machine Learning · Statistics 2025-11-18 Debashis Chatterjee

We aim to produce predictive models that are not only accurate, but are also interpretable to human experts. Our models are decision lists, which consist of a series of if...then... statements (e.g., if high blood pressure, then stroke)…

Applications · Statistics 2015-11-06 Benjamin Letham , Cynthia Rudin , Tyler H. McCormick , David Madigan

Patient-level health economic data collected alongside clinical trials are an important component of the process of technology appraisal, with a view to informing resource allocation decisions. For end of life treatments, such as cancer…

Applications · Statistics 2020-11-24 Andrea Gabrio

Task vectors capture how a model changes during fine-tuning by recording the difference between pre-trained and task-specific weights. The composition of task vectors, a key operator in task arithmetic, enables models to integrate knowledge…

Machine Learning · Computer Science 2025-09-24 Boyuan Zhang , Yingjun Du , Xiantong Zhen , Ling Shao

Analysis of somatic mutation profiles from cancer patients is essential in the development of cancer research. However, the low frequency of most mutations and the varying rates of mutations across patients makes the data extremely…

Tensor decomposition is a powerful computational tool for multiway data analysis. Many popular tensor decomposition approaches---such as the Tucker decomposition and CANDECOMP/PARAFAC (CP)---amount to multi-linear factorization. They are…

Machine Learning · Computer Science 2012-01-17 Zenglin Xu , Feng Yan , Yuan , Qi

Latent class models are powerful statistical modeling tools widely used in psychological, behavioral, and social sciences. In the modern era of data science, researchers often have access to response data collected from large-scale surveys…

Methodology · Statistics 2025-01-08 Zhenghao Zeng , Yuqi Gu , Gongjun Xu

We introduce an online tensor decomposition based approach for two latent variable modeling problems namely, (1) community detection, in which we learn the latent communities that the social actors in social networks belong to, and (2)…

Machine Learning · Computer Science 2015-10-06 Furong Huang , U. N. Niranjan , Mohammad Umar Hakeem , Animashree Anandkumar

Respiratory diseases kill million of people each year. Diagnosis of these pathologies is a manual, time-consuming process that has inter and intra-observer variability, delaying diagnosis and treatment. The recent COVID-19 pandemic has…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Juan E. Arco , A. Ortiz , J. Ramirez , F. J. Martinez-Murcia , Yu-Dong Zhang , Juan M. Gorriz

In conducting non-linear dimensionality reduction and feature learning, it is common to suppose that the data lie near a lower-dimensional manifold. A class of model-based approaches for such problems includes latent variables in an unknown…

Machine Learning · Statistics 2020-08-20 Deborshee Sen , Theodore Papamarkou , David Dunson

Modeling the complex relationships between multiple categorical response variables as a function of predictors is a fundamental task in the analysis of categorical data. However, existing methods can be difficult to interpret and may lack…

Methodology · Statistics 2024-10-08 Hongru Zhao , Aaron J. Molstad , Adam J. Rothman

High-dimensional health and surveillance studies often involve many collinear predictors, multiple correlated outcomes of different types, and latent heterogeneity across observational units. We propose a Bayesian latent-cluster…

Methodology · Statistics 2026-05-13 Hsin-Hsiung Huang , Suyeon Kang
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