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Accurately estimating parameters of physiological models is essential to achieving reliable digital twins. For Type 1 Diabetes, this is particularly challenging due to the complexity of glucose-insulin interactions. Traditional methods…

Diabetic Retinopathy (DR) is a serious and common complication of diabetes, caused by prolonged high blood sugar levels that damage the small retinal blood vessels. If left untreated, DR can progress to retinal vein occlusion and stimulate…

Image and Video Processing · Electrical Eng. & Systems 2025-04-07 Mohammad Reza Yousefi , Ali Bakrani , Amin Dehghani

Blood glucose prediction is an important component of biomedical technology for managing diabetes with automated insulin delivery systems. Machine learning and deep learning algorithms hold the potential to advance this technology. However,…

Software Engineering · Computer Science 2024-06-14 Miriam K. Wolff , Sam Royston , Anders Lyngvi Fougner , Hans Georg Schaathun , Martin Steinert , Rune Volden

Research in diabetes, especially when it comes to building data-driven models to forecast future glucose values, is hindered by the sensitive nature of the data. Because researchers do not share the same data between studies, progress is…

Quantitative Methods · Quantitative Biology 2020-09-10 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

The conventional method of glucose measurement such as pricking blood from the body is prevalent which brings pain and trauma. Invasive methods of measurement sometimes raise the risk of blood infection to the patient. Sometimes, some of…

Medical Physics · Physics 2023-08-24 Prateek Jain , Amit Joshi , Saraju Mohanty

Diabetes is a chronic condition, considered one of the civilization diseases, that is characterized by sustained high blood sugar levels. There is no doubt that more and more people is going to suffer from diabetes, hence it is crucial to…

Other Quantitative Biology · Quantitative Biology 2024-05-21 Kamila Barylska , Anna Gogolińska

Deep sequence models for blood glucose forecasting consistently fail to leverage clinically informative drivers--insulin, meals, and activity--despite well-understood physiological mechanisms. We term this Driver-Blindness and formalize it…

Machine Learning · Computer Science 2025-11-26 Heman Shakeri

Continuous glucose monitoring (CGM) data has revolutionized the management of type 1 diabetes, particularly when integrated with insulin pumps to mitigate clinical events such as hypoglycemia. Recently, there has been growing interest in…

Diabetes is a global epidemic and it is increasing at an alarming rate. The International Diabetes Federation (IDF) projected that the total number of people with diabetes globally may increase by 48%, from 425 million (year 2017) to 629…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Wei Xiang Lim , Zhiyuan Chen , Amr Ahmed , Tissa Chandesa , Iman Liao

The role played by physical activity in slowing down the progression of type-2 diabetes is well recognized. However, except for general clinical guidelines, quantitative real-time estimates of the recommended amount of physical activity,…

Systems and Control · Electrical Eng. & Systems 2025-03-13 Pierluigi Francesco De Paola , Alessandro Borri , Alessia Paglialonga , Pasquale Palumbo , Fabrizio Dabbene

Continuous Glucose Monitoring (CGM) has enabled important opportunities for diabetes management. This study explores the use of CGM data as input for digital decision support tools. We investigate how Recurrent Neural Networks (RNNs) can be…

Background: Diabetes is associated with obesity, poor glucose control and sleep dysfunction which impair cognitive and psychomotor functions, and, in turn, increase driver risk. How this risk plays out in the real-world driving settings is…

Augmented accuracy in prediction of diabetes will open up new frontiers in health prognostics. Data overfitting is a performance-degrading issue in diabetes prognosis. In this study, a prediction system for the disease of diabetes is…

Computer Vision and Pattern Recognition · Computer Science 2017-07-27 Akm Ashiquzzaman , Abdul Kawsar Tushar , Md. Rashedul Islam , Jong-Myon Kim

Comorbid chronic conditions are common among people with type 2 diabetes. We developed an Artificial Intelligence algorithm, based on Reinforcement Learning (RL), for personalized diabetes and multi-morbidity management with strong…

Computers and Society · Computer Science 2020-11-05 Hua Zheng , Ilya O. Ryzhov , Wei Xie , Judy Zhong

Diabetes is a major public health challenge worldwide. Abnormal physiology in diabetes, particularly hypoglycemia, can cause driver impairments that affect safe driving. While diabetes driver safety has been previously researched, few…

Understanding the complex relationships of biomarkers in diabetes is pivotal for advancing treatment strategies, a pressing need in diabetes research. This study applies Bayesian network structure learning to analyze the Shanghai Type 1 and…

Quantitative Methods · Quantitative Biology 2024-06-26 Yuyang Sun , Jingyu Lei , Panagiotis Kosmas

In this work, we investigate uncertainty-aware neural network models for blood glucose prediction and adverse glycemic event identification in Type 1 diabetes. We consider three families of sequence models based on LSTM, GRU, and…

Machine Learning · Computer Science 2026-03-31 Hai Siong Tan , Rafe McBeth

Traditional models of glucose-insulin dynamics rely on heuristic parameterizations chosen to fit observations within a laboratory setting. However, these models cannot describe glucose dynamics in daily life. One source of failure is in…

Machine Learning · Computer Science 2023-05-17 Ke Alexander Wang , Matthew E. Levine , Jiaxin Shi , Emily B. Fox

In this paper, we present a model free approach to calculate long-acting insulin doses for Type 2 Diabetic (T2D) subjects in order to bring their blood glucose (BG) concentration to be within a safe range. The proposed strategy tunes the…

Systems and Control · Electrical Eng. & Systems 2022-12-29 Mohamad Al Ahdab , Torben Knudsen , Jakob Stoustrup , John Leth

Artificial intelligence (AI) will pave the way to a new era in medicine. However, currently available AI systems do not interact with a patient, e.g., for anamnesis, and thus are only used by the physicians for predictions in diagnosis or…

Computers and Society · Computer Science 2019-08-29 Sebastian Spänig , Agnes Emberger-Klein , Jan-Peter Sowa , Ali Canbay , Klaus Menrad , Dominik Heider