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Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Artificial Intelligence · Computer Science 2025-08-22 Ziyuan Huang , Vishaldeep Kaur Sekhon , Roozbeh Sadeghian , Maria L. Vaida , Cynthia Jo , Doyle Ward , Vanni Bucci , John P. Haran

Malaria remains a significant global health burden, particularly in resource-limited regions where timely and accurate diagnosis is critical to effective treatment and control. Deep Learning (DL) has emerged as a transformative tool for…

Machine Learning · Computer Science 2025-01-03 Kiswendsida Kisito Kabore , Desire Guel

Machine learning methods in healthcare have traditionally focused on using data from a single modality, limiting their ability to effectively replicate the clinical practice of integrating multiple sources of information for improved…

Machine Learning · Computer Science 2024-02-13 Felix Krones , Umar Marikkar , Guy Parsons , Adam Szmul , Adam Mahdi

The process of data mining produces various patterns from a given data source. The most recognized data mining tasks are the process of discovering frequent itemsets, frequent sequential patterns, frequent sequential rules and frequent…

Databases · Computer Science 2014-02-13 Thabet Slimani , Amor Lazzez

Antibiotic resistant bacteria are a serious threat to public health system. In order to be able to model the spread of this pathogens within healthcare system network, it is necessary to obtain information on patient movements and the…

Applications · Statistics 2022-06-16 M. J. Piotrowska , J. Rymuza , K. Sakowski

Advancements in artificial intelligence (AI) have transformed many scientific fields, with microbiology and microbiome research now experiencing significant breakthroughs through machine learning applications. This review provides a…

Quantitative Methods · Quantitative Biology 2025-12-19 Xu-Wen Wang , Tong Wang , Yang-Yu Liu

Antibiotic resistance poses a significant threat in in-patient settings with high mortality. Using MIMIC-III data, we generated Sentence-BERT embeddings from clinical notes and applied Neural Networks and XGBoost to predict antibiotic…

Computation and Language · Computer Science 2025-09-19 Mahmoud Alwakeel , Michael E. Yarrington , Rebekah H. Wrenn , Ethan Fang , Jian Pei , Anand Chowdhury , An-Kwok Ian Wong

Microbes are everywhere, including in and on our bodies, and have been shown to play key roles in a variety of prevalent human diseases. Consequently, there has been intense interest in the design of bacteriotherapies or "bugs as drugs,"…

Machine Learning · Statistics 2020-04-13 Travis E. Gibson , Georg K. Gerber

Neural network-based approaches can achieve high accuracy in various medical image segmentation tasks. However, they generally require large labelled datasets for supervised learning. Acquiring and manually labelling a large medical dataset…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Chen Chen , Chen Qin , Huaqi Qiu , Cheng Ouyang , Shuo Wang , Liang Chen , Giacomo Tarroni , Wenjia Bai , Daniel Rueckert

We introduce and discuss a kinetic framework describing the time evolution of the statistical distributions of a population divided into the compartments of susceptible, infectious, recovered, and resistant in the presence of a microbial…

Populations and Evolution · Quantitative Biology 2026-05-07 Marco Menale , Giuseppe Toscani , Mattia Zanella

Machine learning is expected to fuel significant improvements in medical care. To ensure that fundamental principles such as beneficence, respect for human autonomy, prevention of harm, justice, privacy, and transparency are respected,…

Optical microscopy is an indispensable tool in life sciences research, but conventional techniques require compromises between imaging parameters like speed, resolution, field-of-view, and phototoxicity. To overcome these limitations,…

Quantitative Methods · Quantitative Biology 2024-04-01 Leonor Morgado , Estibaliz Gómez-de-Mariscal , Hannah S. Heil , Ricardo Henriques

Malwares are continuously growing in sophistication and numbers. Over the last decade, remarkable progress has been achieved in anti-malware mechanisms. However, several pressing issues (e.g., unknown malware samples detection) still need…

Cryptography and Security · Computer Science 2021-01-22 Zahid Akhtar

Heart disease is one of the significant challenges in today's world and one of the leading causes of many deaths worldwide. Recent advancement of machine learning (ML) application demonstrates that using electrocardiogram (ECG) and patient…

Machine Learning · Computer Science 2021-12-14 Md Manjurul Ahsan , Zahed Siddique

Machine learning (ML) models show strong promise for new biomedical prediction tasks, but concerns about trustworthiness have hindered their clinical adoption. In particular, it is often unclear whether a model relies on true clinical cues…

Machine Learning · Computer Science 2026-01-13 Dushan N. Wadduwage , Dineth Jayakody , Leonidas Zimianitis

Antibiotic resistance presents a growing global health crisis, demanding new therapeutic strategies that target novel bacterial mechanisms. Recent advances in protein structure prediction and machine learning-driven molecule generation…

Biomolecules · Quantitative Biology 2025-05-22 Maximilian G. Schuh , Joshua Hesse , Stephan A. Sieber

As cyber attacks continue to increase in frequency and sophistication, detecting malware has become a critical task for maintaining the security of computer systems. Traditional signature-based methods of malware detection have limitations…

Cryptography and Security · Computer Science 2024-03-05 Khatoon Mohammed

One important problem in microbiome analysis is to identify the bacterial taxa that are associated with a response, where the microbiome data are summarized as the composition of the bacterial taxa at different taxonomic levels. This paper…

Applications · Statistics 2016-03-04 Pixu Shi , Anru Zhang , Hongzhe Li

Pathogenic bacteria present a large disease burden on human health. Control of these pathogens is hampered by rampant lateral gene transfer, whereby pathogenic strains may acquire genes conferring resistance to common antibiotics. Here we…

Populations and Evolution · Quantitative Biology 2014-06-06 Kevin J. Emmett , Raul Rabadan

In the age of digital epidemiology, epidemiologists are faced by an increasing amount of data of growing complexity and dimensionality. Machine learning is a set of powerful tools that can help to analyze such enormous amounts of data. This…

Machine Learning · Statistics 2026-02-19 Marvin N. Wright , Lukas Burk , Pegah Golchian , Jan Kapar , Niklas Koenen , Sophie Hanna Langbein
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