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The emergence and spread of deadly pandemics has repeatedly occurred throughout history, causing widespread infections and loss of life. The rapid spread of pandemics have made governments across the world adopt a range of actions,…

Populations and Evolution · Quantitative Biology 2024-01-15 Marianna Karapitta , Andreas Kasis , Charithea Stylianides , Kleanthis Malialis , Panayiotis Kolios

This paper deals with the problem of estimating variables in nonlinear models for the spread of disease and its application to the COVID-19 epidemic. First unconstrained methods are revisited and they are shown to correspond to the…

Optimization and Control · Mathematics 2020-08-20 Mauricio C. de Oliveira

The vast majority of models for the spread of communicable diseases are parametric in nature and involve underlying assumptions about how the disease spreads through a population. In this article we consider the use of Bayesian…

Methodology · Statistics 2017-06-12 Theodore Kypraios , Philip D. O'Neill

The COVID-19 pandemic has plagued the world for months. The U.S. has taken measures to counter it. On a daily basis, newly confirmed cases have been reported. In the early days, these numbers showed an increasing trend. Recently, the…

Physics and Society · Physics 2020-05-21 Xiubin Bruce Wang , Chaolun Ma

We propose a mathematical model based on probability theory to optimize COVID-19 testing by a multi-step batch testing approach with variable batch sizes. This model and simulation tool dramatically increase the efficiency and efficacy of…

Methodology · Statistics 2021-01-11 Hongshik Ahn , Haoran Jiang , Xiaolin Li

Developing the ability to comprehensively study infections in small populations enables us to improve epidemic models and better advise individuals about potential risks to their health. We currently have a limited understanding of how…

Applications · Statistics 2014-10-14 Wen Dong , Katherine A. Heller , Alex Sandy Pentland

The COVID-19 pandemic has led to significant changes in how people are currently living their lives. To determine how to best reduce the effects of the pandemic and start reopening societies, governments have drawn insights from…

Other Quantitative Biology · Quantitative Biology 2020-09-08 Heather Z. Brooks , Unchitta Kanjanasaratool , Yacoub H. Kureh , Mason A. Porter

Modeling the spread of infections on networks is a well-studied and important field of research. Most infection and diffusion models require a real value or probability on the edges of the network as an input, but this is rarely available…

Social and Information Networks · Computer Science 2017-06-26 Andras Bota , Lauren Gardner

Infectious disease modeling is used to forecast epidemics and assess the effectiveness of intervention strategies. Although the core assumption of mass-action models of homogeneously mixed population is often implausible, they are…

Physics and Society · Physics 2024-08-29 Thien-Minh Le , Jukka-Pekka Onnela

Our paper investigates distributions of exposed and infectious time periods in an epidemic model and how applying a disease control strategy affects the model's accuracy. While ordinary differential equations are widely used for their…

Populations and Evolution · Quantitative Biology 2018-09-28 Adrienna Bingham , Leah B. Shaw

In Part 1, we introduced a stochastic model of an infectious disease, based on the BDI (birth and death with immigration) process. We showed that random processes defined by this model can capture the essence of the stochastic, often…

Populations and Evolution · Quantitative Biology 2021-01-28 Hisashi Kobayashi

We consider multiple diseases spreading in a static Configuration Model network. We make standard assumptions that infection transmits from neighbor to neighbor at a disease-specific rate and infected individuals recover at a…

Populations and Evolution · Quantitative Biology 2015-06-11 Joel C. Miller

In this paper, we develop a method to estimate the infection-rate of a disease, over a region, as a field that varies in space and time. To do so, we use time-series of case-counts of symptomatic patients as observed in the areal units that…

Applications · Statistics 2024-06-19 Cosmin Safta , Wyatt Bridgman , Jaideep Ray

This monograph provides an overview of the mathematical theories and computational algorithm design for contagion source detection in large networks. By leveraging network centrality as a tool for statistical inference, we can accurately…

Social and Information Networks · Computer Science 2023-07-11 Chee Wei Tan , Pei-Duo Yu

Infectious diseases occur when pathogens from other individuals or animals infect a person, resulting in harm to both individuals and society as a whole. The outbreak of such diseases can pose a significant threat to human health. However,…

Populations and Evolution · Quantitative Biology 2024-10-24 Ghazaleh Babanejaddehaki , Aijun An , Manos Papagelis

Estimation of prevalence of undocumented SARS-CoV-2 infections is critical for understanding the overall impact of the Covid-19 disease. In fact, unveiling uncounted cases has fundamental implications for public policy interventions…

Physics and Society · Physics 2022-01-31 Luigi Palatella , Fabio Vanni , David Lambert

Epidemiological models with constant parameters may not capture satisfactory infection patterns in the presence of pharmaceutical and non-pharmaceutical mitigation measures during a pandemic, since infectiousness is a function of time. In…

Populations and Evolution · Quantitative Biology 2022-05-16 K. D. Olumoyin , A. Q. M. Khaliq , K. M. Furati

Many disease models focus on characterizing the underlying transmission mechanism but make simple, possibly naive assumptions about how infections are reported. In this note, we use a simple deterministic Susceptible-Infected-Removed (SIR)…

Populations and Evolution · Quantitative Biology 2019-11-28 Sang Woo Park , Benjamin M. Bolker

Controlling infectious diseases is a major health priority because they can spread and infect humans, thus evolving into epidemics or pandemics. Therefore, early detection of infectious diseases is a significant need, and many researchers…

Machine Learning · Computer Science 2022-06-16 Eman Yahia Alqaissi , Fahd Saleh Alotaibi , Muhammad Sher Ramzan

The basic reproduction number, $R_0$, is a well-known quantifier of epidemic spread. However, a class of existing methods for estimating $R_0$ from incidence data early in the epidemic can lead to an over-estimation of this quantity. In…

Populations and Evolution · Quantitative Biology 2024-03-27 Wajid Ali , Christopher E. Overton , Robert R. Wilkinson , Kieran J. Sharkey