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Customized hardware accelerators have been developed to provide improved performance and efficiency for DNN inference and training. However, the existing hardware accelerators may not always be suitable for handling various DNN models as…

Hardware Architecture · Computer Science 2021-04-07 Xiaofan Zhang , Hanchen Ye , Deming Chen

Computational protein design is experiencing a transformation driven by AI/ML. However, the range of potential protein sequences and structures is astronomically vast, even for moderately sized proteins. Hence, achieving convergence between…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-09 Aymen Alsaadi , Jonathan Ash , Mikhail Titov , Matteo Turilli , Andre Merzky , Shantenu Jha , Sagar Khare

The global demand for sustainable protein sources has accelerated the need for intelligent tools that can rapidly process and synthesise domain-specific scientific knowledge. In this study, we present a proof-of-concept multi-agent…

Artificial Intelligence · Computer Science 2025-06-26 Alexander D. Kalian , Jaewook Lee , Stefan P. Johannesson , Lennart Otte , Christer Hogstrand , Miao Guo

In today's era of "scale-out", this paper makes the case that a specialized hardware architecture based on "scale-in"--placing as many specialized processors as possible along with their memory systems and interconnect links within one or…

Hardware Architecture · Computer Science 2020-09-14 Suresh Krishna , Ravi Krishna

Artificial intelligence (AI) is increasingly deployed in real-time and energy-constrained environments, driving demand for hardware platforms that can deliver high performance and power efficiency. While central processing units (CPUs) and…

Hardware Architecture · Computer Science 2026-01-28 Aybars Yunusoglu , Talha Coskun , Hiruna Vishwamith , Murat Isik , I. Can Dikmen

Protein inference plays a vital role in the proteomics study. Two major approaches could be used to handle the problem of protein inference; top-down and bottom-up. This paper presents a framework for protein inference, which uses hardware…

Computational Engineering, Finance, and Science · Computer Science 2014-03-07 S. M. Vidanagamachchi , S. D. Dewasurendra , R. G. Ragel

Optical computing has been recently proposed as a new compute paradigm to meet the demands of future AI/ML workloads in datacenters and supercomputers. However, proposed implementations so far suffer from lack of scalability, large…

Hardware Architecture · Computer Science 2022-10-21 Daniel Sturm , Sajjad Moazeni

The plethora of complex artificial intelligence (AI) algorithms and available high performance computing (HPC) power stimulates the expeditious development of AI components with heterogeneous designs. Consequently, the need for cross-stack…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-03-16 Zhixiang Ren , Yongheng Liu , Tianhui Shi , Lei Xie , Yue Zhou , Jidong Zhai , Youhui Zhang , Yunquan Zhang , Wenguang Chen

During the last years, algorithms known as Convolutional Neural Networks (CNNs) had become increasingly popular, expanding its application range to several areas. In particular, the image processing field has experienced a remarkable…

Hardware Architecture · Computer Science 2024-08-27 Federico Nicolas Peccia , Luciano Ferreyro , Alejandro Furfaro

Primary motivation for this work was the need to implement hardware accelerators for a newly proposed ANN structure called Auto Resonance Network (ARN) for robotic motion planning. ARN is an approximating feed-forward hierarchical and…

Neural and Evolutionary Computing · Computer Science 2024-02-02 Shilpa Mayannavar , Uday Wali

Machine learning (ML) is successful in achieving human-level artificial intelligence in various fields. However, it lacks the ability to explain an outcome due to its black-box nature. While recent efforts on explainable AI (XAI) has…

Machine Learning · Computer Science 2023-05-09 Zhixin Pan , Prabhat Mishra

This article presents design techniques proposed for efficient hardware implementation of feedforward artificial neural networks (ANNs) under parallel and time-multiplexed architectures. To reduce their design complexity, after the weights…

Hardware Architecture · Computer Science 2021-08-05 Mohammadreza Esmali Nojehdeh , Sajjad Parvin , Mustafa Altun

Automatic algorithm-hardware co-design for DNN has shown great success in improving the performance of DNNs on FPGAs. However, this process remains challenging due to the intractable search space of neural network architectures and hardware…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Zhen Dong , Yizhao Gao , Qijing Huang , John Wawrzynek , Hayden K. H. So , Kurt Keutzer

Machine learning and the use of neural networks has increased precipitously over the past few years primarily due to the ever-increasing accessibility to data and the growth of computation power. It has become increasingly easy to harness…

Machine Learning · Computer Science 2020-08-05 Aaron Hein , Casey Cole , Homayoun Valafar

Artificial Neural Networks (ANN) have been popularized in many science and technological areas due to their capacity to solve many complex pattern matching problems. That is the case of Virtual Screening, a research area that studies how to…

Neural and Evolutionary Computing · Computer Science 2020-06-05 Christian F. Frasser , Carola de Benito , Vincent Canals , Miquel Roca , Pedro J. Ballester , Josep L. Rossello

Implementing Deep Neural Networks (DNNs) on resource-constrained edge devices is a challenging task that requires tailored hardware accelerator architectures and a clear understanding of their performance characteristics when executing the…

Accelerator-based heterogeneous architectures, such as CPU-GPU, CPU-TPU, and CPU-FPGA systems, are widely adopted to support the popular artificial intelligence (AI) algorithms that demand intensive computation. When deployed in real-time…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-20 An Zou , Yuankai Xu , Yinchen Ni , Jintao Chen , Yehan Ma , Jing Li , Christopher Gill , Xuan Zhang , Yier Jin

In this paper, we present a novel technique to search for hardware architectures of accelerators optimized for end-to-end training of deep neural networks (DNNs). Our approach addresses both single-device and distributed pipeline and tensor…

Hardware Architecture · Computer Science 2024-04-24 Muhammad Adnan , Amar Phanishayee , Janardhan Kulkarni , Prashant J. Nair , Divya Mahajan

We now need more than ever to make genome analysis more intelligent. We need to read, analyze, and interpret our genomes not only quickly, but also accurately and efficiently enough to scale the analysis to population level. There currently…

Writing high-performance code requires significant expertise in the programming language, compiler optimizations, and hardware knowledge. This often leads to poor productivity and portability and is inconvenient for a non-programmer…

Performance · Computer Science 2020-09-01 Ajitesh Srivastava , Naifeng Zhang , Rajgopal Kannan , Viktor K. Prasanna
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