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Scarcity of annotated data, particularly for rare or atypical morphologies, present significant challenges for cell and nuclei segmentation in computational pathology. While manual annotation is labor-intensive and costly, synthetic data…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Dominik Winter , Mai Bui , Monica Azqueta Gavaldon , Nicolas Triltsch , Marco Rosati , Nicolas Brieu

Acquiring and annotating surgical data is often resource-intensive, ethical constraining, and requiring significant expert involvement. While generative AI models like text-to-image can alleviate data scarcity, incorporating spatial…

Computer Vision and Pattern Recognition · Computer Science 2025-01-16 Aditya Bhat , Rupak Bose , Chinedu Innocent Nwoye , Nicolas Padoy

Medical image classification is one of the most critical problems in the image recognition area. One of the major challenges in this field is the scarcity of labelled training data. Additionally, there is often class imbalance in datasets…

Image and Video Processing · Electrical Eng. & Systems 2022-09-29 Khushboo Mehra , Hassan Soliman , Soumya Ranjan Sahoo

The purpose of this study is to present and compare three denoising diffusion probabilistic models (DDPMs) that generate 3D $T_1$-weighted MRI human brain images. Three DDPMs were trained using 80,675 image volumes from 42,406 subjects…

Image and Video Processing · Electrical Eng. & Systems 2025-11-03 Samuel W. Remedios , Aaron Carass , Jerry L. Prince , Blake E. Dewey

Ventricular volume and its progression are known to be linked to several brain diseases such as dementia and schizophrenia. Therefore accurate measurement of ventricle volume is vital for longitudinal studies on these disorders, making…

Computer Vision and Pattern Recognition · Computer Science 2018-03-06 Mohsen Ghafoorian , Jonas Teuwen , Rashindra Manniesing , Frank-Erik de Leeuw , Bram van Ginneken , Nico Karssemeijer , Bram Platel

Manual brain tumor segmentation from MRI scans is challenging due to tumor heterogeneity, scarcity of annotated data, and class imbalance in medical imaging datasets. Synthetic data generated by generative models has the potential to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Aditi Jahagirdar , Sameer Joshi

Aside from offering state-of-the-art performance in medical image generation, denoising diffusion probabilistic models (DPM) can also serve as a representation learner to capture semantic information and potentially be used as an image…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Chun-Mei Feng

Despite the significant success achieved by deep learning methods in medical image segmentation, researchers still struggle in the computer-aided diagnosis of abdominal lymph nodes due to the complex abdominal environment, small and…

Image and Video Processing · Electrical Eng. & Systems 2026-02-13 Yongrui Yu , Hanyu Chen , Zitian Zhang , Qiong Xiao , Wenhui Lei , Linrui Dai , Yu Fu , Hui Tan , Guan Wang , Peng Gao , Xiaofan Zhang

Medical image analysis has become a prominent area where machine learning has been applied. However, high quality, publicly available data is limited either due to patient privacy laws or the time and cost required for experts to annotate…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Daniel Saragih , Atsuhiro Hibi , Pascal Tyrrell

This study introduces Polyp-DDPM, a diffusion-based method for generating realistic images of polyps conditioned on masks, aimed at enhancing the segmentation of gastrointestinal (GI) tract polyps. Our approach addresses the challenges of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Zolnamar Dorjsembe , Hsing-Kuo Pao , Furen Xiao

Recent advancements in deep learning for medical image segmentation are often limited by the scarcity of high-quality training data.While diffusion models provide a potential solution by generating synthetic images, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Jianhao Xie , Ziang Zhang , Zhenyu Weng , Yuesheng Zhu , Guibo Luo

Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Xi Zhu , Wei Zhang , Yijie Li , Lauren J. O'Donnell , Fan Zhang

Creating a dataset for training supervised machine learning algorithms can be a demanding task. This is especially true for medical image segmentation since one or more specialists are usually required for image annotation, and creating…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Matheus Viana da Silva , Natália de Carvalho Santos , Julie Ouellette , Baptiste Lacoste , Cesar Henrique Comin

In recent years, Denoising Diffusion Models have demonstrated remarkable success in generating semantically valuable pixel-wise representations for image generative modeling. In this study, we propose a novel end-to-end framework, called…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Zhaohu Xing , Liang Wan , Huazhu Fu , Guang Yang , Lei Zhu

Convolutional neural networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they have not demonstrated sufficiently accurate and robust results for clinical use. In addition, they are…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Guotai Wang , Wenqi Li , Maria A. Zuluaga , Rosalind Pratt , Premal A. Patel , Michael Aertsen , Tom Doel , Anna L. David , Jan Deprest , Sebastien Ourselin , Tom Vercauteren

Preterm infants (born between 28 and 37 weeks of gestation) face elevated risks of neurodevelopmental delays, making early identification crucial for timely intervention. While deep learning-based volumetric segmentation of brain MRI scans…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Lexin Ren , Jiamiao Lu , Weichuan Zhang , Benqing Wu , Tuo Wang , Yi Liao , Jiapan Guo , Changming Sun , Liang Guo

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

We propose a method for synthesizing cardiac magnetic resonance (MR) images with plausible heart pathologies and realistic appearances for the purpose of generating labeled data for the application of supervised deep-learning (DL) training.…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Sina Amirrajab , Cristian Lorenz , Juergen Weese , Josien Pluim , Marcel Breeuwer

Generating healthy counterfactuals from pathological images holds significant promise in medical imaging, e.g., in anomaly detection or for application of analysis tools that are designed for healthy scans. These counterfactuals should…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Ana Lawry Aguila , Peirong Liu , Marina Crespo Aguirre , Juan Eugenio Iglesias

Fetal brain magnetic resonance imaging (MRI) is crucial for assessing neurodevelopment in utero. However, fetal MRI analysis remains technically challenging due to fetal motion, low signal-to-noise ratio, and the need for complex multi-step…

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