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With the growing interest in foundation models for brain signals, graph-based pretraining has emerged as a promising paradigm for learning transferable representations from connectome data. However, existing contrastive and masked…

Machine Learning · Computer Science 2026-03-10 Xinxu Wei , Rong Zhou , Lifang He , Yu Zhang

The large amount of powder diffraction data for which the corresponding crystal structures have not yet been identified suggests the existence of numerous undiscovered, physically relevant crystal structure prototypes. In this paper, we…

Materials Science · Physics 2024-10-31 Abhijith S. Parackal , Rhys E. A. Goodall , Felix A. Faber , Rickard Armiento

Survival prediction is a complex ordinal regression task that aims to predict the survival coefficient ranking among a cohort of patients, typically achieved by analyzing patients' whole slide images. Existing deep learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Minghao Han , Xukun Zhang , Dingkang Yang , Tao Liu , Haopeng Kuang , Jinghui Feng , Lihua Zhang

We consider representation learning on periodic graphs encoding crystal materials. Different from regular graphs, periodic graphs consist of a minimum unit cell repeating itself on a regular lattice in 3D space. How to effectively encode…

Machine Learning · Computer Science 2022-09-27 Keqiang Yan , Yi Liu , Yuchao Lin , Shuiwang Ji

Dynamic graphs are rife with higher-order interactions, such as co-authorship relationships and protein-protein interactions in biological networks, that naturally arise between more than two nodes at once. In spite of the ubiquitous…

Machine Learning · Computer Science 2021-02-09 Manohar Kaul , Masaaki Imaizumi

Accelerating inverse design of crystalline materials with generative models has significant implications for a range of technologies. Unlike other atomic systems, 3D crystals are invariant to discrete groups of isometries called the space…

Materials Science · Physics 2025-10-27 Rees Chang , Angela Pak , Alex Guerra , Ni Zhan , Nick Richardson , Elif Ertekin , Ryan P. Adams

Accurately and comprehensively representing crystal structures is critical for advancing machine learning in large-scale crystal materials simulations, however, effectively capturing and leveraging the intricate geometric and topological…

Machine Learning · Computer Science 2025-07-22 Liang Zhang , Kong Chen , Yuen Wu

Hypergraph data, which capture multi-way interactions among entities, are increasingly prevalent in the big data era. Generating new hyperlinks from an observed, usually high-dimensional hypergraph is an important yet challenging task with…

Methodology · Statistics 2026-05-14 Shihao Wu , Junyi Yang , Gongjun Xu , Ji Zhu

A novel method for crystal structure prediction, based on metadynamics and evolutionary algorithms, is presented here. This technique can be used to produce efficiently both the ground state and metastable states easily reachable from a…

Materials Science · Physics 2012-06-08 Qiang Zhu , Artem R. Oganov , Andriy O. Lyakhov

Structure-informed protein representation learning is essential for effective protein function annotation and \textit{de novo} design. However, the presence of inherent noise in both crystal and AlphaFold-predicted structures poses…

Biomolecules · Quantitative Biology 2025-03-25 Zhongyue Zhang , Runze Ma , Yanjie Huang , Shuangjia Zheng

Recent DFT (density functional theory) simulations showed that metals have a hitherto overlooked symmetry termed "hidden scale invariance" [Hummel {\em et al.}, Phys. Rev. B {\bf{92}}, 174116 (2015)]. According to isomorph theory, this…

Materials Science · Physics 2019-03-06 Laura Friedeheim , Jeppe C. Dyre , Nicholas P. Bailey

Advancements in generative models have sparked significant interest in generating images while adhering to specific structural guidelines. Scene graph to image generation is one such task of generating images which are consistent with the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Rameshwar Mishra , A V Subramanyam

Diffraction is the most common method to solve for unknown or partially known crystal structures. However, it remains a challenge to determine the crystal structure of a new material that may have nanoscale size or heterogeneities. Here we…

Generating the periodic structure of stable materials is a long-standing challenge for the material design community. This task is difficult because stable materials only exist in a low-dimensional subspace of all possible periodic…

Machine Learning · Computer Science 2022-03-15 Tian Xie , Xiang Fu , Octavian-Eugen Ganea , Regina Barzilay , Tommi Jaakkola

Significant disparities between the features of natural images and those inherent to histopathological images make it challenging to directly apply and transfer pre-trained models from natural images to histopathology tasks. Moreover, the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Zhenfeng Zhuang , Min Cen , Yanfeng Li , Fangyu Zhou , Lequan Yu , Baptiste Magnier , Liansheng Wang

The ionic bonding across the lattice and ordered microscopic structures endow crystals with unique symmetry and determine their macroscopic properties. Unconventional crystals, in particular, exhibit non-traditional lattice structures or…

Materials Science · Physics 2024-11-04 Hongyi Wang , Ji Sun , Jinzhe Liang , Li Zhai , Zitian Tang , Zijian Li , Wei Zhai , Xusheng Wang , Weihao Gao , Sheng Gong

Many problems in computer vision and machine learning can be cast as learning on hypergraphs that represent higher-order relations. Recent approaches for hypergraph learning extend graph neural networks based on message passing, which is…

Machine Learning · Computer Science 2022-08-23 Jinwoo Kim , Saeyoon Oh , Sungjun Cho , Seunghoon Hong

Crystal structure prediction has been a subject of topical interest, but remains a substantial challenge, especially for complex structures as it deals with the global minimization of the extremely rugged high-dimensional potential energy…

Materials Science · Physics 2022-01-26 Xuecheng Shao , Jian Lv , Peng Liu , Sen Shao , Pengyue Gao , Hanyu Liu , Yanchao Wang , Yanming Ma

Soft, porous mechanical metamaterials exhibit pattern transformations that may have important applications in soft robotics, sound reduction and biomedicine. To design these innovative materials, it is important to be able to simulate them…

Soft Condensed Matter · Physics 2025-03-14 Fleur Hendriks , Vlado Menkovski , Martin Doškář , Marc G. D. Geers , Ondřej Rokoš

Scaffold hopping is a drug discovery strategy to generate new chemical entities by modifying the core structure, the \emph{scaffold}, of a known active compound. This approach preserves the essential molecular features of the original…

Biomolecules · Quantitative Biology 2023-08-16 Jos Torge , Charles Harris , Simon V. Mathis , Pietro Lio
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